Lineage for d2az5c_ (2az5 C:)

  1. Root: SCOPe 2.08
  2. 2739516Class b: All beta proteins [48724] (180 folds)
  3. 2777171Fold b.22: TNF-like [49841] (1 superfamily)
    sandwich, 10 strands in 2 sheets; jelly-roll
  4. 2777172Superfamily b.22.1: TNF-like [49842] (2 families) (S)
  5. 2777173Family b.22.1.1: TNF-like [49843] (15 proteins)
  6. 2777391Protein Tumor necrosis factor (TNF) [49848] (3 species)
  7. 2777392Species Human (Homo sapiens) [TaxId:9606] [49849] (33 PDB entries)
  8. 2777413Domain d2az5c_: 2az5 C: [127601]
    automated match to d1tnfa_
    complexed with 307

Details for d2az5c_

PDB Entry: 2az5 (more details), 2.1 Å

PDB Description: crystal structure of tnf-alpha with a small molecule inhibitor
PDB Compounds: (C:) Tumor necrosis factor (TNF-alpha) (Tumor necrosis factor ligand superfamily member 2) (TNF-a) (Cachectin) [Contains: Tumor necrosis factor, membrane form; Tumor necrosis factor, soluble form]

SCOPe Domain Sequences for d2az5c_:

Sequence, based on SEQRES records: (download)

>d2az5c_ b.22.1.1 (C:) Tumor necrosis factor (TNF) {Human (Homo sapiens) [TaxId: 9606]}

Sequence, based on observed residues (ATOM records): (download)

>d2az5c_ b.22.1.1 (C:) Tumor necrosis factor (TNF) {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d2az5c_:

Click to download the PDB-style file with coordinates for d2az5c_.
(The format of our PDB-style files is described here.)

Timeline for d2az5c_: