Lineage for Protein: Aldose reductase (aldehyde reductase)

  1. Root: SCOPe 2.07
  2. 2413226Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2413227Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. 2415941Superfamily c.1.7: NAD(P)-linked oxidoreductase [51430] (2 families) (S)
  5. 2415942Family c.1.7.1: Aldo-keto reductases (NADP) [51431] (16 protein domains)
    Common fold covers whole protein structure
  6. 2416006Protein Aldose reductase (aldehyde reductase) [51436] (2 species)

Species:

  1. 2416007Human (Homo sapiens) [TaxId:9606] [51437] (138 PDB entries)
    Uniprot P15121
    1. Domain for 1abn:
    2. Domain for 1ads:
    3. Domain for 1az1:
    4. Domain for 1az2:
    5. Domains for 1ef3:
      1. 2416142Domain d1ef3a_: 1ef3 A: [28680]
        complexed with fid, nap
      2. 2416143Domain d1ef3b_: 1ef3 B: [28681]
        complexed with fid, nap
    6. Domain for 1el3:
    7. Domain for 1iei:
    8. Domain for 1mar:
    9. Domain for 1pwl:
    10. Domain for 1pwm:
    11. Domain for 1t40:
    12. Domain for 1t41:
    13. Domain for 1us0:
    14. Domain for 1x96:
    15. Domain for 1x97:
    16. Domain for 1x98:
    17. Domain for 1xgd:
    18. Domain for 1zua:
    19. Domain for 2acq:
    20. Domain for 2acr:
    21. Domain for 2acs:
    22. Domain for 2acu:
    23. Domain for 2agt:
    24. Domain for 2alr:
    25. Domain for 2f2k:
    26. Domain for 2fz8:
    27. Domain for 2fz9:
    28. Domain for 2fzb:
    29. Domain for 2fzd:
    30. Domain for 2ine:
    31. Domain for 2inz:
    32. Domain for 2ipw:
    33. Domain for 2iq0:
    34. Domain for 2iqd:
    35. Domain for 2is7:
    36. Domain for 2isf:
    37. Domain for 2pd5:
    38. Domain for 2pd9:
    39. Domain for 2pdb:
    40. Domain for 2pdc:
    41. Domain for 2pdf:
    42. Domain for 2pdg:
    43. Domain for 2pdh:
    44. Domain for 2pdi:
    45. Domain for 2pdj:
    46. Domain for 2pdk:
    47. Domain for 2pdl:
    48. Domain for 2pdm:
    49. Domain for 2pdn:
    50. Domain for 2pdp:
    51. Domain for 2pdq:
    52. Domain for 2pdu:
    53. Domain for 2pdw:
    54. Domain for 2pdx:
    55. Domain for 2pdy:
    56. Domain for 2pev:
    57. Domain for 2pf8:
    58. Domain for 2pfh:
    59. Domain for 2pzn:
    60. Domain for 3dn5:
    61. Domain for 3g5e:
    62. Domain for 3ghr:
    63. Domain for 3ghs:
    64. Domain for 3ght:
    65. Domain for 3ghu:
    66. Domain for 3lbo:
    67. Domain for 3ld5:
    68. Domain for 3len:
    69. Domain for 3lep:
    70. Domain for 3lqg:
    71. Domain for 3lql:
    72. Domain for 3lz3:
    73. Domain for 3lz5:
    74. Domain for 3m0i:
    75. Domain for 3m4h:
    76. Domain for 3m64:
    77. Domain for 3mb9:
    78. Domain for 3mc5:
    79. Domain for 3onb:
    80. Domain for 3onc:
    81. Domain for 3p2v:
    82. Domains for 3q65:
      1. 2416120Domain d3q65a_: 3q65 A: [184227]
        automated match to d1el3a_
        complexed with gol, nap, so4
      2. 2416121Domain d3q65b_: 3q65 B: [184228]
        automated match to d1el3a_
        complexed with gol, nap, so4
    83. Domains for 3q67:
      1. 2416072Domain d3q67a_: 3q67 A: [184229]
        automated match to d1el3a_
        complexed with nap, so4; mutant
      2. 2416073Domain d3q67b_: 3q67 B: [184230]
        automated match to d1el3a_
        complexed with nap, so4; mutant
    84. Domain for 3rx2:
    85. Domain for 3rx3:
    86. Domain for 3rx4:
    87. Domain for 3s3g:
    88. Domain for 3t42:
    89. Domain for 3v35:
    90. Domain for 3v36:
    91. Domain for 3v9q:
    92. Domain for 4ga8:
    93. Domain for 4gab:
    94. Domain for 4gca:
    95. Domain for 4gq0:
    96. Domain for 4gqg:
    97. Domain for 4i5x:
    98. Domain for 4icc:
    99. Domain for 4igs:
    100. Domain for 4jih:
    101. Domain for 4jii:
    102. Domain for 4jir:
    103. Domain for 4lau:
    104. Domain for 4laz:
    105. Domain for 4lb3:
    106. Domain for 4lb4:
    107. Domain for 4lbr:
    108. Domain for 4lbs:
    109. Domain for 4nkc:
    110. Domain for 4pr4:
    111. Domain for 4prr:
    112. Domain for 4prt:
    113. Domain for 4puu:
    114. Domain for 4puw:
    115. Domain for 4q7b:
    116. Domain for 4qbx:
    117. Domain for 4qr6:
    118. Domain for 4qx4:
    119. Domain for 4qxi:
    120. Domain for 4rpq:
    121. Domain for 4wev:
    122. Domains for 4xzh:
      1. 2416042Domain d4xzha_: 4xzh A: [279510]
        automated match to d1pwma_
        complexed with 48i, nap
      2. 2416043Domain d4xzhb_: 4xzh B: [279512]
        automated match to d1pwma_
        complexed with 48i, nap
    123. Domain for 4xzi:
    124. Domain for 4xzl:
    125. Domain for 4xzm:
    126. Domain for 4xzn:
    127. Domain for 4ys1:
    128. Domain for 4yu1:
    129. Domains for 5ha7:
      1. 2416110Domain d5ha7a_: 5ha7 A: [323322]
        automated match to d1pwma_
        complexed with nap, so4, wy1
      2. 2416111Domain d5ha7b_: 5ha7 B: [323389]
        automated match to d1pwma_
        complexed with nap, so4, wy1
    130. Domain for 5lik:
    131. Domain for 5liu:
    132. Domain for 5liw:
    133. Domain for 5lix:
    134. Domain for 5liy:
    135. Domain for 5m2f:
    136. Domain for 5ou0:
    137. Domain for 5ouj:
    138. Domain for 5ouk:
  2. 2416148Pig (Sus scrofa) [TaxId:9823] [51438] (12 PDB entries)
    1. Domain for 1ae4:
    2. Domain for 1ah0:
    3. Domain for 1ah3:
    4. Domain for 1ah4:
    5. Domain for 1cwn:
    6. Domains for 1dla:
      1. 2416160Domain d1dlaa_: 1dla A: [28690]
        CA-atoms only
      2. 2416161Domain d1dlab_: 1dla B: [28691]
        CA-atoms only
      3. 2416162Domain d1dlac_: 1dla C: [28692]
        CA-atoms only
      4. 2416163Domain d1dlad_: 1dla D: [28693]
        CA-atoms only
    7. Domain for 1eko:
    8. Domain for 1hqt:
    9. Domain for 2ao0:
    10. Domain for 3cv7:
    11. Domain for 3fx4:
    12. Domain for 3h4g:

More info for Protein Aldose reductase (aldehyde reductase) from c.1.7.1: Aldo-keto reductases (NADP)

Timeline for Protein Aldose reductase (aldehyde reductase) from c.1.7.1: Aldo-keto reductases (NADP):