PDB entry 5ou0

View 5ou0 on RCSB PDB site
Description: Crystal structure of human AKR1B1 complexed with NADP+ and compound 37
Class: oxidoreductase
Keywords: alpha-beta TIM barrel, cytosol, aldo-keto reductase, pyrimido[4, 5-c]quinolone-2-acetic acid scaffold, oxidoreductase
Deposited on 2017-08-23, released 2018-05-09
The last revision prior to the SCOPe 2.07 freeze date was dated 2018-05-09, with a file datestamp of 2018-05-04.
Experiment type: XRAY
Resolution: 0.94 Å
R-factor: N/A
AEROSPACI score: 0.89 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: aldose reductase
    Species: Homo sapiens [TaxId:9606]
    Gene: AKR1B1, ALDR1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P15121 (0-315)
      • conflict (4)
    Domains in SCOPe 2.07: d5ou0a_
  • Heterogens: AV5, NAP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >5ou0A (A:)