Lineage for Family c.1.7.1: Aldo-keto reductases (NADP)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2078560Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. 2080913Superfamily c.1.7: NAD(P)-linked oxidoreductase [51430] (2 families) (S)
  5. 2080914Family c.1.7.1: Aldo-keto reductases (NADP) [51431] (16 protein domains)
    Common fold covers whole protein structure

Protein Domains:

  1. 20809152,5-diketo-D-gluconic acid reductase A [51443] (3 species)
    1. 2080916Species Corynebacterium sp. [TaxId:1720] [51444] (3 PDB entries)
    2. 2080920Species Escherichia coli [TaxId:562] [102053] (1 PDB entry)
    3. 2080923Species Thermotoga maritima [TaxId:2336] [117365] (1 PDB entry)
      Uniprot Q9X0A2
  2. 208092620alpha-hydroxysteroid dehydrogenase [109609] (2 species)
    1. 2080927Species Human (Homo sapiens) [TaxId:9606] [109610] (1 PDB entry)
    2. 2080929Species Rabbit (Oryctolagus cuniculus) [TaxId:9986] [110348] (2 PDB entries)
      Uniprot P80508
  3. 20809343-alpha-hydroxysteroid dehydrogenase [51439] (2 species)
    1. 2080935Species Human (Homo sapiens), type III [TaxId:9606] [69383] (15 PDB entries)
      bile acid binding protein
    2. 2080964Species Norway rat (Rattus norvegicus) [TaxId:10116] [51440] (3 PDB entries)
  4. 2080970Aflatoxin aldehyde reductase (akr7a1) [75056] (1 species)
  5. 2080974Aldose reductase (aldehyde reductase) [51436] (2 species)
    1. 2080975Species Human (Homo sapiens) [TaxId:9606] [51437] (135 PDB entries)
      Uniprot P15121
    2. 2081106Species Pig (Sus scrofa) [TaxId:9823] [51438] (12 PDB entries)
  6. 2081122CHO reductase [51441] (1 species)
  7. 2081125FR-1 (fibroblast growth factor-induced) protein [51432] (1 species)
  8. 2081128Hypothetical oxidoreductase YdhF [89459] (1 species)
  9. 2081134Hypothetical protein C07D8.6 [102049] (1 species)
    Aldo-keto reductase family 1 member c1
  10. 2081137Prostaglandin d2 11-ketoreductase (akr1c3) [102051] (1 species)
    Aldo-keto reductase family 1 member c3
  11. 2081191Putative oxidoreductase IolS [102054] (1 species)
    vegetative protein 147, VEG147, AKR11A
  12. 2081195Putative oxidoreductase YhdN [102056] (1 species)
    General stress protein 69, GSP69, AKR11B
  13. 2081199Tas protein [89461] (1 species)
  14. 2081203Voltage-dependent K+ channel beta subunit [51434] (1 species)
  15. 2081223Xylose reductase [75058] (1 species)
  16. 2081255automated matches [190169] (5 species)
    not a true protein
    1. 2081256Species Human (Homo sapiens) [TaxId:9606] [188399] (45 PDB entries)
    2. 2081331Species Mouse (Mus musculus) [TaxId:10090] [187524] (12 PDB entries)
    3. 2081363Species Norway rat (Rattus norvegicus) [TaxId:10116] [186935] (2 PDB entries)
    4. 2081368Species Salmonella enterica [TaxId:99287] [259716] (1 PDB entry)
    5. 2081372Species Yersinia pestis [TaxId:632] [228396] (1 PDB entry)

More info for Family c.1.7.1: Aldo-keto reductases (NADP)

Timeline for Family c.1.7.1: Aldo-keto reductases (NADP):