Lineage for Family c.1.7.1: Aldo-keto reductases (NADP)

  1. Root: SCOPe 2.08
  2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. Fold c.1: TIM beta/alpha-barrel [51350] (34 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. Superfamily c.1.7: NAD(P)-linked oxidoreductase [51430] (2 families) (S)
  5. Family c.1.7.1: Aldo-keto reductases (NADP) [51431] (16 proteins)
    Common fold covers whole protein structure

Proteins:

  1. 2,5-diketo-D-gluconic acid reductase A [51443] (3 species)
    1. Species Corynebacterium sp. [TaxId:1720] [51444] (3 PDB entries)
    2. Species Escherichia coli [TaxId:562] [102053] (1 PDB entry)
    3. Species Thermotoga maritima [TaxId:2336] [117365] (1 PDB entry)
      Uniprot Q9X0A2
  2. 20alpha-hydroxysteroid dehydrogenase [109609] (2 species)
    1. Species Human (Homo sapiens) [TaxId:9606] [109610] (1 PDB entry)
    2. Species Rabbit (Oryctolagus cuniculus) [TaxId:9986] [110348] (2 PDB entries)
      Uniprot P80508
  3. 3-alpha-hydroxysteroid dehydrogenase [51439] (2 species)
    1. Species Human (Homo sapiens), type III [TaxId:9606] [69383] (16 PDB entries)
      bile acid binding protein
    2. Species Norway rat (Rattus norvegicus) [TaxId:10116] [51440] (3 PDB entries)
  4. Aflatoxin aldehyde reductase (akr7a1) [75056] (1 species)
  5. Aldose reductase (aldehyde reductase) [51436] (2 species)
    1. Species Human (Homo sapiens) [TaxId:9606] [51437] (156 PDB entries)
      Uniprot P15121
    2. Species Pig (Sus scrofa) [TaxId:9823] [51438] (12 PDB entries)
  6. CHO reductase [51441] (1 species)
  7. FR-1 (fibroblast growth factor-induced) protein [51432] (1 species)
  8. Hypothetical oxidoreductase YdhF [89459] (1 species)
  9. Hypothetical protein C07D8.6 [102049] (1 species)
    Aldo-keto reductase family 1 member c1
  10. Prostaglandin d2 11-ketoreductase (akr1c3) [102051] (1 species)
    Aldo-keto reductase family 1 member c3
  11. Putative oxidoreductase IolS [102054] (1 species)
    vegetative protein 147, VEG147, AKR11A
  12. Putative oxidoreductase YhdN [102056] (1 species)
    General stress protein 69, GSP69, AKR11B
  13. Tas protein [89461] (1 species)
  14. Voltage-dependent K+ channel beta subunit [51434] (1 species)
  15. Xylose reductase [75058] (1 species)
  16. automated matches [190169] (7 species)
    not a true protein
    1. Species Debaryomyces nepalensis [TaxId:27299] [360097] (2 PDB entries)
    2. Species Human (Homo sapiens) [TaxId:9606] [188399] (46 PDB entries)
    3. Species Mouse (Mus musculus) [TaxId:10090] [187524] (12 PDB entries)
    4. Species Norway rat (Rattus norvegicus) [TaxId:10116] [186935] (2 PDB entries)
    5. Species Salmonella enterica [TaxId:99287] [259716] (1 PDB entry)
    6. Species Scheffersomyces stipitis [TaxId:322104] [360899] (2 PDB entries)
    7. Species Yersinia pestis [TaxId:632] [228396] (1 PDB entry)

More info for Family c.1.7.1: Aldo-keto reductases (NADP)

Timeline for Family c.1.7.1: Aldo-keto reductases (NADP):