Lineage for d4i5xa1 (4i5x A:1-316)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2078560Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. 2080913Superfamily c.1.7: NAD(P)-linked oxidoreductase [51430] (2 families) (S)
  5. 2080914Family c.1.7.1: Aldo-keto reductases (NADP) [51431] (16 protein domains)
    Common fold covers whole protein structure
  6. 2080974Protein Aldose reductase (aldehyde reductase) [51436] (2 species)
  7. 2080975Species Human (Homo sapiens) [TaxId:9606] [51437] (135 PDB entries)
    Uniprot P15121
  8. 2081098Domain d4i5xa1: 4i5x A:1-316 [228451]
    Other proteins in same PDB: d4i5xa2
    automated match to d4gqga_
    complexed with flf, nap

Details for d4i5xa1

PDB Entry: 4i5x (more details), 2.1 Å

PDB Description: Crystal Structure Of AKR1B10 Complexed With NADP+ And Flufenamic acid
PDB Compounds: (A:) Aldo-keto reductase family 1 member B10

SCOPe Domain Sequences for d4i5xa1:

Sequence; same for both SEQRES and ATOM records: (download)

>d4i5xa1 c.1.7.1 (A:1-316) Aldose reductase (aldehyde reductase) {Human (Homo sapiens) [TaxId: 9606]}
matfvelstkakmpivglgtwksplgkvkeavkvaidagyrhidcayvyqnehevgeaiq
ekiqekavkredlfivsklwptfferplvrkafektlkdlklsyldvylihwpqgfksgd
dlfpkddkgnaiggkatfldaweameelvdeglvkalgvsnfshfqiekllnkpglkykp
vtnqvechpyltqekliqychskgitvtaysplgspdrpwakpedpslledpkikeiaak
hkktaaqvlirfhiqrnvivipksvtpariveniqvfdfklsdeematilsfnrnwracn
vlqsshledypfdaey

SCOPe Domain Coordinates for d4i5xa1:

Click to download the PDB-style file with coordinates for d4i5xa1.
(The format of our PDB-style files is described here.)

Timeline for d4i5xa1:

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Domains from same chain:
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d4i5xa2