PDB entry 4q7b

View 4q7b on RCSB PDB site
Description: Human Aldose Reductase complexed with a ligand with an IDD structure ([2-(benzylcarbamoyl)-5-fluorophenoxy]acetic acid) at 1.19 A
Class: oxidoreductase/oxidoreductase inhibitor
Keywords: TIM BARREL, OXIDOREDUCTASE, oxidoreductase-oxidoreductase inhibitor complex
Deposited on 2014-04-24, released 2015-06-10
The last revision prior to the SCOPe 2.08 freeze date was dated 2015-06-10, with a file datestamp of 2015-06-05.
Experiment type: XRAY
Resolution: 1.19 Å
R-factor: N/A
AEROSPACI score: 0.66 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: aldose reductase
    Species: Homo sapiens [TaxId:9606]
    Gene: AKR1B1, ALDR1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P15121 (0-314)
      • see remark 999 (3)
    Domains in SCOPe 2.08: d4q7ba_
  • Heterogens: NAP, 2YZ, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >4q7bA (A:)