PDB entry 4lau

View 4lau on RCSB PDB site
Description: Crystal structure of human AR complexed with NADP+ and {2-[(4-bromobenzyl)carbamoyl]-5-chlorophenoxy}acetic acid
Class: oxidoreductase
Keywords: TIM barrel, oxidoreductase, diabetes, Halogenated compound, Cytosolic
Deposited on 2013-06-20, released 2014-04-30
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-15, with a file datestamp of 2017-11-10.
Experiment type: XRAY
Resolution: 0.84 Å
R-factor: N/A
AEROSPACI score: 1.02 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: aldose reductase
    Species: Homo sapiens [TaxId:9606]
    Gene: AKR1B1, ALDR1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P15121 (0-315)
      • see remark 999 (4)
    Domains in SCOPe 2.08: d4laua_
  • Heterogens: NAP, W8X, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >4lauA (A:)