Lineage for d2fz8a_ (2fz8 A:)

  1. Root: SCOPe 2.08
  2. 2826024Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2826025Fold c.1: TIM beta/alpha-barrel [51350] (34 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. 2829136Superfamily c.1.7: NAD(P)-linked oxidoreductase [51430] (2 families) (S)
  5. 2829137Family c.1.7.1: Aldo-keto reductases (NADP) [51431] (16 proteins)
    Common fold covers whole protein structure
  6. 2829201Protein Aldose reductase (aldehyde reductase) [51436] (2 species)
  7. 2829202Species Human (Homo sapiens) [TaxId:9606] [51437] (156 PDB entries)
    Uniprot P15121
  8. 2829276Domain d2fz8a_: 2fz8 A: [134421]
    automated match to d1pwla_
    complexed with nap, zst

Details for d2fz8a_

PDB Entry: 2fz8 (more details), 1.48 Å

PDB Description: Human Aldose reductase complexed with inhibitor zopolrestat at 1.48 A(1 day soaking).
PDB Compounds: (A:) aldose reductase

SCOPe Domain Sequences for d2fz8a_:

Sequence; same for both SEQRES and ATOM records: (download)

>d2fz8a_ c.1.7.1 (A:) Aldose reductase (aldehyde reductase) {Human (Homo sapiens) [TaxId: 9606]}
asrillnngakmpilglgtwksppgqvteavkvaidvgyrhidcahvyqnenevgvaiqe
klreqvvkreelfivsklwctyhekglvkgacqktlsdlkldyldlylihwptgfkpgke
ffpldesgnvvpsdtnildtwaameelvdeglvkaigisnfnhlqvemilnkpglkykpa
vnqiechpyltqekliqycqskgivvtaysplgspdrpwakpedpslledprikaiaakh
nkttaqvlirfpmqrnlvvipksvtperiaenfkvfdfelssqdmttllsynrnwrvcal
lsctshkdypfheef

SCOPe Domain Coordinates for d2fz8a_:

Click to download the PDB-style file with coordinates for d2fz8a_.
(The format of our PDB-style files is described here.)

Timeline for d2fz8a_: