Lineage for d2fz8a_ (2fz8 A:)

  1. Root: SCOPe 2.07
  2. 2434694Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2434695Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. 2437818Superfamily c.1.7: NAD(P)-linked oxidoreductase [51430] (2 families) (S)
  5. 2437819Family c.1.7.1: Aldo-keto reductases (NADP) [51431] (16 proteins)
    Common fold covers whole protein structure
  6. 2437883Protein Aldose reductase (aldehyde reductase) [51436] (2 species)
  7. 2437884Species Human (Homo sapiens) [TaxId:9606] [51437] (155 PDB entries)
    Uniprot P15121
  8. 2437957Domain d2fz8a_: 2fz8 A: [134421]
    automated match to d1pwla_
    complexed with nap, zst

Details for d2fz8a_

PDB Entry: 2fz8 (more details), 1.48 Å

PDB Description: Human Aldose reductase complexed with inhibitor zopolrestat at 1.48 A(1 day soaking).
PDB Compounds: (A:) aldose reductase

SCOPe Domain Sequences for d2fz8a_:

Sequence; same for both SEQRES and ATOM records: (download)

>d2fz8a_ c.1.7.1 (A:) Aldose reductase (aldehyde reductase) {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d2fz8a_:

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Timeline for d2fz8a_: