Lineage for d3p2va_ (3p2v A:)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2078560Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. 2080913Superfamily c.1.7: NAD(P)-linked oxidoreductase [51430] (2 families) (S)
  5. 2080914Family c.1.7.1: Aldo-keto reductases (NADP) [51431] (16 protein domains)
    Common fold covers whole protein structure
  6. 2080974Protein Aldose reductase (aldehyde reductase) [51436] (2 species)
  7. 2080975Species Human (Homo sapiens) [TaxId:9606] [51437] (135 PDB entries)
    Uniprot P15121
  8. 2081056Domain d3p2va_: 3p2v A: [196219]
    automated match to d2pf8a_
    complexed with doy, nap

Details for d3p2va_

PDB Entry: 3p2v (more details), 1.69 Å

PDB Description: Novel Benzothiazepine Inhibitor in Complex with human Aldose Reductase
PDB Compounds: (A:) aldose reductase

SCOPe Domain Sequences for d3p2va_:

Sequence; same for both SEQRES and ATOM records: (download)

>d3p2va_ c.1.7.1 (A:) Aldose reductase (aldehyde reductase) {Human (Homo sapiens) [TaxId: 9606]}
masrillnngakmpilglgtwksppgqvteavkvaidvgyrhidcahvyqnenevgvaiq
eklreqvvkreelfivsklwctyhekglvkgacqktlsdlkldyldlylihwptgfkpgk
effpldesgnvvpsdtnildtwaameelvdeglvkaigisnfnhlqvemilnkpglkykp
avnqiechpyltqekliqycqskgivvtaysplgspdrpwakpedpslledprikaiaak
hnkttaqvlirfpmqrnlvvipksvtperiaenfkvfdfelssqdmttllsynrnwrvca
llsctshkdypfheef

SCOPe Domain Coordinates for d3p2va_:

Click to download the PDB-style file with coordinates for d3p2va_.
(The format of our PDB-style files is described here.)

Timeline for d3p2va_: