Lineage for Species: Human (Homo sapiens), different isozymes [TaxId: 9606]

  1. Root: SCOPe 2.07
  2. 2413226Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2426096Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 2426097Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families) (S)
  5. 2426098Family c.2.1.1: Alcohol dehydrogenase-like, C-terminal domain [51736] (17 proteins)
    N-terminal all-beta domain defines family
  6. 2426119Protein Alcohol dehydrogenase [51737] (9 species)
  7. 2426236Species Human (Homo sapiens), different isozymes [TaxId:9606] [51739] (24 PDB entries)
    Uniprot P00326 ! Uniprot P00325 ! Uniprot P07327

PDB entries in Species: Human (Homo sapiens), different isozymes [TaxId: 9606]:

  1. Domain(s) for 1agn:
    1. 2426277Domain d1agna2: 1agn A:163-338 [29753]
      Other proteins in same PDB: d1agna1, d1agnb1, d1agnc1, d1agnd1
      sigma isozyme
      complexed with act, nad, zn
    2. 2426278Domain d1agnb2: 1agn B:163-338 [29754]
      Other proteins in same PDB: d1agna1, d1agnb1, d1agnc1, d1agnd1
      sigma isozyme
      complexed with act, nad, zn
    3. 2426279Domain d1agnc2: 1agn C:163-338 [29755]
      Other proteins in same PDB: d1agna1, d1agnb1, d1agnc1, d1agnd1
      sigma isozyme
      complexed with act, nad, zn
    4. 2426280Domain d1agnd2: 1agn D:163-338 [29756]
      Other proteins in same PDB: d1agna1, d1agnb1, d1agnc1, d1agnd1
      sigma isozyme
      complexed with act, nad, zn
  2. Domain(s) for 1d1s:
    1. 2426269Domain d1d1sa2: 1d1s A:163-338 [29743]
      Other proteins in same PDB: d1d1sa1, d1d1sb1, d1d1sc1, d1d1sd1
      sigma isozyme
      complexed with act, cac, nad, zn
    2. 2426270Domain d1d1sb2: 1d1s B:163-338 [29744]
      Other proteins in same PDB: d1d1sa1, d1d1sb1, d1d1sc1, d1d1sd1
      sigma isozyme
      complexed with act, cac, nad, zn
    3. 2426271Domain d1d1sc2: 1d1s C:163-338 [29745]
      Other proteins in same PDB: d1d1sa1, d1d1sb1, d1d1sc1, d1d1sd1
      sigma isozyme
      complexed with act, cac, nad, zn
    4. 2426272Domain d1d1sd2: 1d1s D:163-338 [29746]
      Other proteins in same PDB: d1d1sa1, d1d1sb1, d1d1sc1, d1d1sd1
      sigma isozyme
      complexed with act, cac, nad, zn
  3. Domain(s) for 1d1t:
    1. 2426263Domain d1d1ta2: 1d1t A:163-338 [29735]
      Other proteins in same PDB: d1d1ta1, d1d1tb1, d1d1tc1, d1d1td1
      sigma isozyme
      complexed with act, cac, nad, zn; mutant
    2. 2426264Domain d1d1tb2: 1d1t B:163-338 [29736]
      Other proteins in same PDB: d1d1ta1, d1d1tb1, d1d1tc1, d1d1td1
      sigma isozyme
      complexed with act, cac, nad, zn; mutant
    3. 2426265Domain d1d1tc2: 1d1t C:163-338 [29737]
      Other proteins in same PDB: d1d1ta1, d1d1tb1, d1d1tc1, d1d1td1
      sigma isozyme
      complexed with act, cac, nad, zn; mutant
    4. 2426266Domain d1d1td2: 1d1t D:163-338 [29738]
      Other proteins in same PDB: d1d1ta1, d1d1tb1, d1d1tc1, d1d1td1
      sigma isozyme
      complexed with act, cac, nad, zn; mutant
  4. Domain(s) for 1deh:
    1. 2426251Domain d1deha2: 1deh A:163-338 [29729]
      Other proteins in same PDB: d1deha1, d1dehb1
      complexed with cl, nad, pyz, zn
    2. 2426252Domain d1dehb2: 1deh B:163-338 [29730]
      Other proteins in same PDB: d1deha1, d1dehb1
      complexed with cl, nad, pyz, zn
  5. Domain(s) for 1hdx:
    1. 2426283Domain d1hdxa2: 1hdx A:163-338 [29733]
      Other proteins in same PDB: d1hdxa1, d1hdxb1
      complexed with cl, cxl, nad, zn
    2. 2426284Domain d1hdxb2: 1hdx B:163-338 [29734]
      Other proteins in same PDB: d1hdxa1, d1hdxb1
      complexed with cl, cxl, nad, zn
  6. Domain(s) for 1hdy:
    1. 2426285Domain d1hdya2: 1hdy A:163-338 [29739]
      Other proteins in same PDB: d1hdya1, d1hdyb1
      complexed with cl, nad, pyz, zn
    2. 2426286Domain d1hdyb2: 1hdy B:163-338 [29740]
      Other proteins in same PDB: d1hdya1, d1hdyb1
      complexed with cl, nad, pyz, zn
  7. Domain(s) for 1hdz:
    1. 2426287Domain d1hdza2: 1hdz A:163-338 [29741]
      Other proteins in same PDB: d1hdza1, d1hdzb1
      complexed with cl, nad, zn
    2. 2426288Domain d1hdzb2: 1hdz B:163-338 [29742]
      Other proteins in same PDB: d1hdza1, d1hdzb1
      complexed with cl, nad, zn
  8. Domain(s) for 1hso:
    1. 2426275Domain d1hsoa2: 1hso A:163-338 [29747]
      Other proteins in same PDB: d1hsoa1, d1hsob1
      alpha isozyme
      complexed with nad, pyz, zn
    2. 2426276Domain d1hsob2: 1hso B:163-338 [29748]
      Other proteins in same PDB: d1hsoa1, d1hsob1
      alpha isozyme
      complexed with nad, pyz, zn
  9. Domain(s) for 1hsz:
    1. 2426249Domain d1hsza2: 1hsz A:163-338 [29727]
      Other proteins in same PDB: d1hsza1, d1hszb1
      beta-1 isozyme
      complexed with nad, po4, zn
    2. 2426250Domain d1hszb2: 1hsz B:163-338 [29728]
      Other proteins in same PDB: d1hsza1, d1hszb1
      beta-1 isozyme
      complexed with nad, po4, zn
  10. Domain(s) for 1ht0:
    1. 2426241Domain d1ht0a2: 1ht0 A:163-338 [29725]
      Other proteins in same PDB: d1ht0a1, d1ht0b1
      gamma-2 isozyme
      complexed with nad, zn
    2. 2426242Domain d1ht0b2: 1ht0 B:163-338 [29726]
      Other proteins in same PDB: d1ht0a1, d1ht0b1
      gamma-2 isozyme
      complexed with nad, zn
  11. Domain(s) for 1htb:
    1. 2426259Domain d1htba2: 1htb A:163-338 [29731]
      Other proteins in same PDB: d1htba1, d1htbb1
      complexed with cl, nad, pyz, zn
    2. 2426260Domain d1htbb2: 1htb B:163-338 [29732]
      Other proteins in same PDB: d1htba1, d1htbb1
      complexed with cl, nad, pyz, zn
  12. Domain(s) for 1m6h:
    1. 2426239Domain d1m6ha2: 1m6h A:163-338 [74530]
      Other proteins in same PDB: d1m6ha1, d1m6hb1
      glutathione-dependent formaldehyde dehydrogenase
      complexed with k, po4, zn
    2. 2426240Domain d1m6hb2: 1m6h B:163-338 [74532]
      Other proteins in same PDB: d1m6ha1, d1m6hb1
      glutathione-dependent formaldehyde dehydrogenase
      complexed with k, po4, zn
  13. Domain(s) for 1m6w:
    1. 2426255Domain d1m6wa2: 1m6w A:163-338 [74569]
      Other proteins in same PDB: d1m6wa1, d1m6wb1
      glutathione-dependent formaldehyde dehydrogenase
      complexed with 12h, k, po4, zn
    2. 2426256Domain d1m6wb2: 1m6w B:163-338 [74571]
      Other proteins in same PDB: d1m6wa1, d1m6wb1
      glutathione-dependent formaldehyde dehydrogenase
      complexed with 12h, k, po4, zn
  14. Domain(s) for 1ma0:
    1. 2426253Domain d1ma0a2: 1ma0 A:163-338 [74606]
      Other proteins in same PDB: d1ma0a1, d1ma0b1
      glutathione-dependent formaldehyde dehydrogenase
      complexed with dao, k, nad, po4, zn
    2. 2426254Domain d1ma0b2: 1ma0 B:163-338 [74608]
      Other proteins in same PDB: d1ma0a1, d1ma0b1
      glutathione-dependent formaldehyde dehydrogenase
      complexed with dao, k, nad, po4, zn
  15. Domain(s) for 1mc5:
    1. 2426267Domain d1mc5a2: 1mc5 A:163-338 [84930]
      Other proteins in same PDB: d1mc5a1, d1mc5b1
      glutathione-dependent formaldehyde dehydrogenase
      complexed with ahe, k, nad, po4, zn
    2. 2426268Domain d1mc5b2: 1mc5 B:163-338 [84932]
      Other proteins in same PDB: d1mc5a1, d1mc5b1
      glutathione-dependent formaldehyde dehydrogenase
      complexed with ahe, k, nad, po4, zn
  16. Domain(s) for 1mp0:
    1. 2426247Domain d1mp0a2: 1mp0 A:163-338 [79371]
      Other proteins in same PDB: d1mp0a1, d1mp0b1
      glutathione-dependent formaldehyde dehydrogenase
      complexed with k, nad, po4, zn
    2. 2426248Domain d1mp0b2: 1mp0 B:163-338 [79373]
      Other proteins in same PDB: d1mp0a1, d1mp0b1
      glutathione-dependent formaldehyde dehydrogenase
      complexed with k, nad, po4, zn
  17. Domain(s) for 1teh:
    1. 2426273Domain d1teha2: 1teh A:163-338 [29749]
      Other proteins in same PDB: d1teha1, d1tehb1
      glutathione-dependent formaldehyde dehydrogenase
      complexed with nad, zn
    2. 2426274Domain d1tehb2: 1teh B:163-338 [29750]
      Other proteins in same PDB: d1teha1, d1tehb1
      glutathione-dependent formaldehyde dehydrogenase
      complexed with nad, zn
  18. Domain(s) for 1u3t:
    1. 2426281Domain d1u3ta2: 1u3t A:163-338 [113002]
      Other proteins in same PDB: d1u3ta1, d1u3tb1
      complexed with ccb, nad, zn
    2. 2426282Domain d1u3tb2: 1u3t B:163-338 [113004]
      Other proteins in same PDB: d1u3ta1, d1u3tb1
      complexed with ccb, nad, zn
  19. Domain(s) for 1u3u:
    1. 2426243Domain d1u3ua2: 1u3u A:163-338 [113006]
      Other proteins in same PDB: d1u3ua1, d1u3ub1
      complexed with bnf, nad, po4, zn
    2. 2426244Domain d1u3ub2: 1u3u B:163-338 [113008]
      Other proteins in same PDB: d1u3ua1, d1u3ub1
      complexed with bnf, nad, po4, zn
  20. Domain(s) for 1u3v:
    1. 2426245Domain d1u3va2: 1u3v A:163-338 [113010]
      Other proteins in same PDB: d1u3va1, d1u3vb1
      complexed with hpl, nad, po4, zn
    2. 2426246Domain d1u3vb2: 1u3v B:163-338 [113012]
      Other proteins in same PDB: d1u3va1, d1u3vb1
      complexed with hpl, nad, po4, zn
  21. Domain(s) for 1u3w:
    1. 2426237Domain d1u3wa2: 1u3w A:163-338 [113014]
      Other proteins in same PDB: d1u3wa1, d1u3wb1
      complexed with fxy, nad, zn
    2. 2426238Domain d1u3wb2: 1u3w B:163-338 [113016]
      Other proteins in same PDB: d1u3wa1, d1u3wb1
      complexed with fxy, nad, zn
  22. Domain(s) for 2fze:
    1. 2426261Domain d2fzea2: 2fze A:163-338 [134434]
      Other proteins in same PDB: d2fzea1, d2fzeb1
      automated match to d1m6ha2
      complexed with apr, k, po4, zn
    2. 2426262Domain d2fzeb2: 2fze B:163-338 [134436]
      Other proteins in same PDB: d2fzea1, d2fzeb1
      automated match to d1m6ha2
      complexed with apr, k, po4, zn
  23. Domain(s) for 2fzw:
    1. 2426257Domain d2fzwa2: 2fzw A:163-338 [134483]
      Other proteins in same PDB: d2fzwa1, d2fzwb1
      automatically matched to d1m6ha2
      complexed with k, nad, po4, zn; mutant
    2. 2426258Domain d2fzwb2: 2fzw B:163-338 [134485]
      Other proteins in same PDB: d2fzwa1, d2fzwb1
      automatically matched to d1m6ha2
      complexed with k, nad, po4, zn; mutant
  24. Domain(s) for 3hud:
    1. 2426289Domain d3huda2: 3hud A:163-338 [29751]
      Other proteins in same PDB: d3huda1, d3hudb1
      complexed with nad, zn
    2. 2426290Domain d3hudb2: 3hud B:163-338 [29752]
      Other proteins in same PDB: d3huda1, d3hudb1
      complexed with nad, zn

More info for Species Human (Homo sapiens), different isozymes [TaxId:9606] from c.2.1.1 Alcohol dehydrogenase

Timeline for Species Human (Homo sapiens), different isozymes [TaxId:9606] from c.2.1.1 Alcohol dehydrogenase: