Lineage for d2fzwa2 (2fzw A:163-338)

  1. Root: SCOPe 2.08
  2. 2826024Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2841004Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 2841005Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families) (S)
  5. 2841006Family c.2.1.1: Alcohol dehydrogenase-like, C-terminal domain [51736] (19 proteins)
    N-terminal all-beta domain defines family
  6. 2841027Protein Alcohol dehydrogenase [51737] (9 species)
  7. 2841162Species Human (Homo sapiens), different isozymes [TaxId:9606] [51739] (24 PDB entries)
    Uniprot P00326 ! Uniprot P00325 ! Uniprot P07327
  8. 2841179Domain d2fzwa2: 2fzw A:163-338 [134483]
    Other proteins in same PDB: d2fzwa1, d2fzwb1
    automatically matched to d1m6ha2
    complexed with k, nad, po4, zn; mutant

Details for d2fzwa2

PDB Entry: 2fzw (more details), 1.84 Å

PDB Description: structure of the binary complex of the e67l mutant of human glutathione-dependent formaldehyde dehydrogenase with nad(h)
PDB Compounds: (A:) Alcohol dehydrogenase class III chi chain

SCOPe Domain Sequences for d2fzwa2:

Sequence; same for both SEQRES and ATOM records: (download)

>d2fzwa2 c.2.1.1 (A:163-338) Alcohol dehydrogenase {Human (Homo sapiens), different isozymes [TaxId: 9606]}

SCOPe Domain Coordinates for d2fzwa2:

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Timeline for d2fzwa2:

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