Lineage for Protein: 3-isopropylmalate dehydrogenase, IPMDH

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2138632Fold c.77: Isocitrate/Isopropylmalate dehydrogenase-like [53658] (1 superfamily)
    consists of two intertwined (sub)domains related by pseudo dyad; duplication
    3 layers: a/b/a; single mixed beta-sheet of 10 strands, order 213A945867 (A=10); strands from 5 to 9 are antiparallel to the rest
  4. 2138633Superfamily c.77.1: Isocitrate/Isopropylmalate dehydrogenase-like [53659] (6 families) (S)
    the constituent families form similar dimers
  5. 2138634Family c.77.1.1: Dimeric isocitrate & isopropylmalate dehydrogenases [53660] (4 protein domains)
    the active site is between the two identical subunits
  6. 2138635Protein 3-isopropylmalate dehydrogenase, IPMDH [53661] (11 species)

Species:

  1. 2138636Bacillus coagulans [TaxId:1398] [53664] (2 PDB entries)
    1. Domains for 1ayq:
      1. 2138637Domain d1ayqa_: 1ayq A: [302207]
        automated match to d2ayqb_
      2. 2138638Domain d1ayqb_: 1ayq B: [302208]
        automated match to d2ayqb_
    2. Domains for 2ayq:
      1. 2138639Domain d2ayqa_: 2ayq A: [35057]
      2. 2138640Domain d2ayqb_: 2ayq B: [35058]
  2. 2138641Bacillus sp. [TaxId:1409] [254872] (1 PDB entry)
  3. 2138644Chimera (Thermus thermophilus) and (Bacillus subtilis) [TaxId:274] [53663] (2 PDB entries)
    1. Domain for 1xac:
    2. Domain for 1xad:
  4. 2138647Escherichia coli [TaxId:562] [53667] (1 PDB entry)
  5. 2138650Mycobacterium tuberculosis [TaxId:1773] [117725] (2 PDB entries)
    Uniprot P95313
    1. Domains for 1w0d:
      1. 2138651Domain d1w0da1: 1w0d A:1A-336 [114060]
        Other proteins in same PDB: d1w0da2, d1w0db2, d1w0dc2, d1w0dd2
        complexed with so4
      2. 2138652Domain d1w0db1: 1w0d B:1A-336 [114061]
        Other proteins in same PDB: d1w0da2, d1w0db2, d1w0dc2, d1w0dd2
        complexed with so4
      3. 2138653Domain d1w0dc1: 1w0d C:1A-336 [114062]
        Other proteins in same PDB: d1w0da2, d1w0db2, d1w0dc2, d1w0dd2
        complexed with so4
      4. 2138654Domain d1w0dd1: 1w0d D:1A-336 [114063]
        Other proteins in same PDB: d1w0da2, d1w0db2, d1w0dc2, d1w0dd2
        complexed with so4
    2. Domains for 2g4o:
      1. 2138655Domain d2g4oa2: 2g4o A:1A-336 [134604]
        Other proteins in same PDB: d2g4oa3, d2g4ob3, d2g4oc3, d2g4od3
        automated match to d1w0da_
        complexed with cl, so4
      2. 2138656Domain d2g4ob2: 2g4o B:1A-336 [134605]
        Other proteins in same PDB: d2g4oa3, d2g4ob3, d2g4oc3, d2g4od3
        automated match to d1w0da_
        complexed with cl, so4
      3. 2138657Domain d2g4oc2: 2g4o C:1A-336 [134606]
        Other proteins in same PDB: d2g4oa3, d2g4ob3, d2g4oc3, d2g4od3
        automated match to d1w0da_
        complexed with cl, so4
      4. 2138658Domain d2g4od2: 2g4o D:1A-336 [134607]
        Other proteins in same PDB: d2g4oa3, d2g4ob3, d2g4oc3, d2g4od3
        automated match to d1w0da_
        complexed with cl, so4
  6. 2138659Salmonella typhimurium [TaxId:90371] [53666] (1 PDB entry)
  7. 2138662Shewanella benthica [TaxId:43661] [195907] (1 PDB entry)
  8. 2138665Sulfolobus tokodaii [TaxId:111955] [117724] (1 PDB entry)
    Uniprot P50455
  9. 2138668Thermotoga maritima [TaxId:2336] [110714] (1 PDB entry)
    Uniprot Q9WZ26
  10. 2138670Thermus thermophilus [TaxId:274] [53662] (14 PDB entries)
    1. Domains for 1dpz:
      1. 2138691Domain d1dpza_: 1dpz A: [35053]
      2. 2138692Domain d1dpzb_: 1dpz B: [35054]
    2. Domains for 1dr0:
      1. 2138683Domain d1dr0a_: 1dr0 A: [35045]
      2. 2138684Domain d1dr0b_: 1dr0 B: [35046]
    3. Domains for 1dr8:
      1. 2138689Domain d1dr8a_: 1dr8 A: [35051]
      2. 2138690Domain d1dr8b_: 1dr8 B: [35052]
    4. Domain for 1g2u:
    5. Domains for 1gc8:
      1. 2138680Domain d1gc8a_: 1gc8 A: [35042]
      2. 2138681Domain d1gc8b_: 1gc8 B: [35043]
    6. Domain for 1gc9:
    7. Domain for 1hex:
    8. Domain for 1idm:
    9. Domain for 1ipd:
    10. Domains for 1osi:
      1. 2138685Domain d1osia_: 1osi A: [35047]
      2. 2138686Domain d1osib_: 1osi B: [35048]
      3. 2138687Domain d1osic_: 1osi C: [35049]
      4. 2138688Domain d1osid_: 1osi D: [35050]
    11. Domains for 1osj:
      1. 2138676Domain d1osja_: 1osj A: [35039]
      2. 2138677Domain d1osjb_: 1osj B: [35040]
    12. Domain for 1wal:
    13. Domain for 1xaa:
    14. Domain for 1xab:
  11. 2138693Thiobacillus ferrooxidans [TaxId:920] [53665] (1 PDB entry)

More info for Protein 3-isopropylmalate dehydrogenase, IPMDH from c.77.1.1: Dimeric isocitrate & isopropylmalate dehydrogenases

Timeline for Protein 3-isopropylmalate dehydrogenase, IPMDH from c.77.1.1: Dimeric isocitrate & isopropylmalate dehydrogenases: