Lineage for d1xaca_ (1xac A:)

  1. Root: SCOPe 2.08
  2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. Fold c.77: Isocitrate/Isopropylmalate dehydrogenase-like [53658] (1 superfamily)
    consists of two intertwined (sub)domains related by pseudo dyad; duplication
    3 layers: a/b/a; single mixed beta-sheet of 10 strands, order 213A945867 (A=10); strands from 5 to 9 are antiparallel to the rest
  4. Superfamily c.77.1: Isocitrate/Isopropylmalate dehydrogenase-like [53659] (6 families) (S)
    the constituent families form similar dimers
  5. Family c.77.1.1: Dimeric isocitrate & isopropylmalate dehydrogenases [53660] (4 proteins)
    the active site is between the two identical subunits
  6. Protein 3-isopropylmalate dehydrogenase, IPMDH [53661] (11 species)
  7. Species Chimera (Thermus thermophilus) and (Bacillus subtilis) [TaxId:274] [53663] (2 PDB entries)
  8. Domain d1xaca_: 1xac A: [35056]

Details for d1xaca_

PDB Entry: 1xac (more details), 2.1 Å

PDB Description: chimera isopropylmalate dehydrogenase between bacillus subtilis (m) and thermus thermophilus (t) from n-terminal: 20% t middle 20% m residual 60% t, mutated at s82r. low temperature (100k) structure.
PDB Compounds: (A:) 3-isopropylmalate dehydrogenase 2t2m6t s82r

SCOPe Domain Sequences for d1xaca_:

Sequence; same for both SEQRES and ATOM records: (download)

>d1xaca_ c.77.1.1 (A:) 3-isopropylmalate dehydrogenase, IPMDH {Chimera (Thermus thermophilus) and (Bacillus subtilis) [TaxId: 274]}

SCOPe Domain Coordinates for d1xaca_ are not available.

Timeline for d1xaca_: