PDB entry 1g2u

View 1g2u on RCSB PDB site
Description: the structure of the mutant, a172v, of 3-isopropylmalate dehydrogenase from thermus thermophilus hb8 : its thermostability and structure.
Class: oxidoreductase
Keywords: beta-barrel, nad binding, oxidoreductase
Deposited on 2000-10-21, released 2000-11-01
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-10-04, with a file datestamp of 2017-09-29.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: N/A
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 3-isopropylmalate dehydrogenase
    Species: Thermus thermophilus [TaxId:300852]
    Gene: LEU B
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q5SIY4 (0-344)
      • see remark 999 (84)
      • engineered (171)
    Domains in SCOPe 2.08: d1g2ua_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1g2uA (A:)
    mkvavlpgdgigpevteaalkvlraldeaeglglayevfpfggaaidafgepfpeptrkg
    veeaeavllgsvggpkwdglprkirpetgllslrksqdlfanlrpakvfpglerlsplke
    eiargvdvlivreltggiyfgeprgmseaeawnteryskpevervarvafevarkrrkhv
    vsvdkanvlevgefwrktveevgrgypdvalehqyvdamamhlvrsparfdvvvtgnifg
    dilsdlasvlpgslgllpsaslgrgtpvfepvhgsapdiagkgianptaailsaammleh
    afglvelarkvedavakalletpppdlggsagteaftatvlrhla