Class b: All beta proteins [48724] (180 folds) |
Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily) barrel, closed; n=6, S=8; greek-key duplication: consists of two domains of the same fold |
Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families) |
Family b.47.1.2: Eukaryotic proteases [50514] (49 proteins) |
Protein Urokinase-type plasminogen activator (LMW U-PA), catalytic domain [50586] (1 species) |
Species Human (Homo sapiens) [TaxId:9606] [50587] (101 PDB entries) Uniprot P00749 156-178,179-424 |
Domain d1c5w.1: 1c5w A:,B: [26359] complexed with esi, flc |
Domain d1c5x.1: 1c5x A:,B: [26357] complexed with esi, flc |
Domain d1c5y.1: 1c5y A:,B: [26355] complexed with esp, flc |
Domain d1c5z.1: 1c5z A:,B: [26358] complexed with bam, flc |
Domain d1ejna_: 1ejn A: [26356] complexed with agb, so4 |
Domain d1f5ku_: 1f5k U: [59652] complexed with bam, so4 |
Domain d1f5la_: 1f5l A: [59653] complexed with amr, so4 |
Domain d1f92a_: 1f92 A: [59721] complexed with so4, ukp |
Domain d1gi7.1: 1gi7 A:,B: [65214] complexed with 120, cit |
Domain d1gi8.1: 1gi8 A:,B: [65215] complexed with bmz, cit |
Domain d1gi9.1: 1gi9 A:,B: [65216] complexed with 123, cit |
Domain d1gj7.1: 1gj7 A:,B: [70180] complexed with 132, cit |
Domain d1gj8.1: 1gj8 A:,B: [70181] complexed with 133, cit |
Domain d1gj9.1: 1gj9 A:,B: [70182] complexed with 134, cit |
Domain d1gja.1: 1gja A:,B: [70183] complexed with 135, cit |
Domain d1gjb.1: 1gjb A:,B: [70184] complexed with 130, cit |
Domain d1gjc.1: 1gjc A:,B: [70185] complexed with 130, cit |
Domain d1gjd.1: 1gjd A:,B: [70186] complexed with 136, cit |
Domain d1lmw.1: 1lmw A:,B: [26360] complexed with 0gj |
Domain d1lmw.2: 1lmw C:,D: [26361] complexed with 0gj |
Domain d1o3p.1: 1o3p A:,B: [92442] complexed with 655, cit |
Domain d1o5a.1: 1o5a A:,B: [103877] complexed with 696, cit |
Domain d1o5b.1: 1o5b A:,B: [103878] complexed with cit, esi |
Domain d1o5c.1: 1o5c A:,B: [103879] complexed with cit, cr9 |
Domain d1owda_: 1owd A: [93641] complexed with 497 |
Domain d1owea_: 1owe A: [93642] complexed with 675, so4 |
Domain d1owha_: 1owh A: [93643] complexed with 239, so4 |
Domain d1owia_: 1owi A: [93644] complexed with 426 |
Domain d1owja_: 1owj A: [93645] complexed with 155 |
Domain d1owka_: 1owk A: [93646] complexed with 303 |
Domain d1sc8u_: 1sc8 U: [105418] complexed with 2in, so4 |
Domain d1sqaa_: 1sqa A: [98965] complexed with so4, ui1 |
Domain d1sqoa_: 1sqo A: [98967] complexed with so4, ui2 |
Domain d1sqta_: 1sqt A: [98970] complexed with ui3 |
Domain d1t32a_: 1t32 A: [119136] automated match to d1au8a_ complexed with ohh, so4 |
Domain d1u6qa_: 1u6q A: [113074] complexed with 745 |
Domain d1vj9u_: 1vj9 U: [108627] complexed with 5in, so4 |
Domain d1vjau_: 1vja U: [108628] complexed with 7in, so4 |
Domain d1w0zu_: 1w0z U: [145804] automated match to d1ejna_ complexed with si1, so4 |
Domain d1w10u_: 1w10 U: [145805] automated match to d1ejna_ complexed with sj1, so4 |
Domain d1w11u_: 1w11 U: [145806] automated match to d1ejna_ complexed with sk1, so4 |
Domain d1w12u_: 1w12 U: [145807] automated match to d1ejna_ complexed with sl1 |
Domain d1w13u_: 1w13 U: [145808] automated match to d1ejna_ complexed with sm1, so4 |
Domain d1w14u_: 1w14 U: [145809] automated match to d1ejna_ complexed with sh1, so4 |
Domain d2r2wu_: 2r2w U: [151542] automated match to d2vipa1 complexed with 4pg, so4 |
Domain d3kgpa_: 3kgp A: [212351] automated match to d2viva_ complexed with 4az, so4 |
Domain d3khva_: 3khv A: [212357] automated match to d2viva_ complexed with 4al, pge, so4 |
Domain d3kidu_: 3kid U: [212362] automated match to d2viva_ complexed with 2bs |
Domain d3mhwu_: 3mhw U: [181232] automated match to d1ejna_ complexed with abv, so4 |
Domain d3mwiu_: 3mwi U: [181648] automated match to d1ejna_ complexed with b25, so4 |
Domain d4dvau_: 4dva U: [220045] automated match to d4fuba_ complexed with p6g, so4 |
Domain d4dw2u_: 4dw2 U: [220057] Other proteins in same PDB: d4dw2h_, d4dw2l1, d4dw2l2 automated match to d4fuba_ complexed with so4 |
Domain d4fu7a_: 4fu7 A: [221524] automated match to d4fuba_ complexed with 1up, act, so4 |
Domain d4fu8a_: 4fu8 A: [221525] automated match to d4fuba_ complexed with 2up, act, sin, so4 |
Domain d4fu9a_: 4fu9 A: [221526] automated match to d4fuba_ complexed with 675, act, gol, sin, so4 |
Domain d4fuba_: 4fub A: [193570] automated match to d3mwiu_ complexed with 15p, 4up, act, gol, sin, so4 |
Domain d4fuca_: 4fuc A: [221527] automated match to d4fuba_ complexed with 239, act, gol, sin, so4 |
Domain d4fuda_: 4fud A: [221528] automated match to d4fuba_ complexed with 6up, na, sin, so4 |
Domain d4fuea_: 4fue A: [221529] automated match to d4fuba_ complexed with 7up, act, gol, sin, so4 |
Domain d4fufa_: 4fuf A: [221530] automated match to d4fuba_ complexed with 8up, act, gol, sin, so4 |
Domain d4fuga_: 4fug A: [221531] automated match to d4fuba_ complexed with 9up, act, gol, so4 |
Domain d4fuha_: 4fuh A: [221532] automated match to d4fuba_ complexed with 1u2, act, gol, so4 |
Domain d4fuia_: 4fui A: [221533] automated match to d4fuba_ complexed with gol, na, sin, so4, ui3 |
Domain d4fuja_: 4fuj A: [221534] automated match to d4fuba_ complexed with 1u9, act, gol, sin, so4 |
Domain d4h42u_: 4h42 U: [228593] automated match to d2wpis_ complexed with 11e, pg6 |
Domain d4os1a_: 4os1 A: [267095] automated match to d4h42u_ complexed with act, so4 |
Domain d4os2a_: 4os2 A: [267096] automated match to d4h42u_ complexed with act, so4 |
Domain d4os4a_: 4os4 A: [259878] automated match to d4h42u_ complexed with act, cl, gol, so4 |
Domain d4os5a_: 4os5 A: [267097] automated match to d4h42u_ complexed with so4 |
Domain d4os6a_: 4os6 A: [260721] automated match to d4h42u_ complexed with act, so4 |
Domain d4os7a_: 4os7 A: [267098] automated match to d4h42u_ complexed with act, gol, so4 |
Domain d4xsku_: 4xsk U: [311789] automated match to d3pb1e_ complexed with gol, pge, so4; mutant |
Domain d5hgga_: 5hgg A: [317960] Other proteins in same PDB: d5hggs_, d5hggt1, d5hggt2 automated match to d4h42u_ complexed with gol, mes, so4, twn |
Domain d5hggb_: 5hgg B: [317973] Other proteins in same PDB: d5hggs_, d5hggt1, d5hggt2 automated match to d4h42u_ complexed with gol, mes, so4, twn |
Domain d5lhna_: 5lhn A: [336070] Other proteins in same PDB: d5lhnb1, d5lhnb2 automated match to d3mwiu_ complexed with edo, so4 |
Domain d5lhpa_: 5lhp A: [336075] Other proteins in same PDB: d5lhpb1, d5lhpb2 automated match to d3mwiu_ complexed with edo, pbz, so4 |
Domain d5lhqa_: 5lhq A: [336101] Other proteins in same PDB: d5lhqb1, d5lhqb2 automated match to d3mwiu_ complexed with 0gj, edo, so4 |
Domain d5lhra_: 5lhr A: [336067] Other proteins in same PDB: d5lhrb1, d5lhrb2 automated match to d3mwiu_ |
Domain d5lhsa_: 5lhs A: [336016] automated match to d3mwiu_ complexed with ni, so4 |
Domain d5lhsb_: 5lhs B: [336098] automated match to d3mwiu_ complexed with ni, so4 |
Domain d5lhsc_: 5lhs C: [336082] automated match to d3mwiu_ complexed with ni, so4 |
Domain d5lhsd_: 5lhs D: [336112] automated match to d3mwiu_ complexed with ni, so4 |
Domain d5wxsu_: 5wxs U: [354732] automated match to d1kigh_ complexed with 7yf |
Domain d5wxtu_: 5wxt U: [354689] automated match to d1kigh_ complexed with 7yr |
Domain d5xg4u_: 5xg4 U: [337131] automated match to d4h42u_ complexed with pg6, que |
Domain d5yc6u_: 5yc6 U: [358386] automated match to d4h42u_ complexed with pge, pzh, so4 |
Domain d5yc7u_: 5yc7 U: [358379] automated match to d4h42u_ complexed with pzh, so4 |
Domain d5z1cu_: 5z1c U: [361853] automated match to d4h42u_ complexed with zxi |
Domain d5za7u_: 5za7 U: [361567] automated match to d1kigh_ complexed with hmx, so4 |
Domain d5za8u_: 5za8 U: [361555] automated match to d1kigh_ complexed with 27i |
Domain d5za9u_: 5za9 U: [361568] automated match to d1kigh_ complexed with 50i |
Domain d5zaeu_: 5zae U: [361572] automated match to d1kigh_ complexed with eau, so4 |
Domain d5zafu_: 5zaf U: [361571] automated match to d1kigh_ complexed with 28i |
Domain d5zagu_: 5zag U: [361569] automated match to d1kigh_ complexed with 94i |
Domain d5zahu_: 5zah U: [361563] automated match to d1kigh_ complexed with 30i |
Domain d5zaju_: 5zaj U: [361554] automated match to d1kigh_ complexed with 32i |
Domain d5zc5u_: 5zc5 U: [361570] automated match to d1kigh_ complexed with 09i |
Domain d6ag2u_: 6ag2 U: [374089] automated match to d1kigh_ complexed with 9x9, so4 |
Domain d6ag3u_: 6ag3 U: [374090] automated match to d1kigh_ complexed with 9xc |
Domain d6ag7u_: 6ag7 U: [372837] automated match to d4h42u_ complexed with h55 |
Domain d6ag9u_: 6ag9 U: [374091] automated match to d1kigh_ complexed with 9xf, so4 |
Domain d6jypu_: 6jyp U: [385371] automated match to d4h42u_ complexed with hmx, so4 |
Domain d6jyqu_: 6jyq U: [385343] automated match to d4h42u_ complexed with eau, so4 |
Domain d6l04u_: 6l04 U: [390750] automated match to d4h42u_ complexed with 32i |
Domain d6l05u_: 6l05 U: [390884] automated match to d4h42u_ complexed with 50i |
Domain d7dzdu_: 7dzd U: [417989] automated match to d4h42u_ complexed with gbs, pge |
Timeline for Species Human (Homo sapiens) [TaxId:9606] from b.47.1.2 Urokinase-type plasminogen activator (LMW U-PA), catalytic domain: