PDB entry 3kid

View 3kid on RCSB PDB site
Description: The Crystal Structures of 2-Aminobenzothiazole-based Inhibitors in Complexes with Urokinase-type Plasminogen Activator
Class: hydrolase
Keywords: PROTEIN-LIGAND COMPLEX, Disulfide bond, Fibrinolysis, Hydrolase, Plasminogen activation, Serine protease
Deposited on 2009-11-01, released 2009-12-01
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-12-25, with a file datestamp of 2019-12-20.
Experiment type: XRAY
Resolution: 2.71 Å
R-factor: N/A
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'U':
    Compound: urokinase-type plasminogen activator
    Species: Homo sapiens [TaxId:9606]
    Gene: PLAU
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00749 (0-End)
      • engineered (120)
      • engineered (143)
    Domains in SCOPe 2.08: d3kidu_
  • Heterogens: 2BS, HOH

PDB Chain Sequences:

  • Chain 'U':
    Sequence, based on SEQRES records: (download)
    >3kidU (U:)
    iiggefttienqpwfaaiyrrhrggsvtyvcggslispcwvisathcfidypkkedyivy
    lgrsrlnsntqgemkfevenlilhkdysadtlahhndiallkirskegrcaqpsrtiqti
    alpsmyndpqfgtsceitgfgkeqstdylypeqlkmtvvklishrecqqphyygsevttk
    mlcaadpqwktdscqgdsggplvcslqgrmtltgivswgrgcalkdkpgvytrvshflpw
    irshtkeenglal
    

    Sequence, based on observed residues (ATOM records): (download)
    >3kidU (U:)
    iiggefttienqpwfaaiyrrvtyvcggslispcwvisathcfidypkkedyivylgrsr
    lnsntqgemkfevenlilhkdysaahhndiallkirskegrcaqpsrtiqtialpsmynd
    pqfgtsceitgfgkeqstdylypeqlkmtvvklishrecqqphyygsevttkmlcaadpq
    wktdscqgdsggplvcslqgrmtltgivswgrgcalkdkpgvytrvshflpwirshtk