PDB entry 3kgp

View 3kgp on RCSB PDB site
Description: Crystal Structures of Urokinase-type Plasminogen Activator in Complex with 4-(Aminomethyl) Benzoic Acid and 4-(Aminomethyl-phenyl)-methanol
Class: hydrolase
Keywords: PROTEIN-LIGAND COMPLEX, Disulfide bond, Fibrinolysis, Hydrolase, Plasminogen activation, Serine protease
Deposited on 2009-10-29, released 2009-12-01
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-12-25, with a file datestamp of 2019-12-20.
Experiment type: XRAY
Resolution: 2.35 Å
R-factor: N/A
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: urokinase-type plasminogen activator
    Species: Homo sapiens [TaxId:9606]
    Gene: PLAU
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00749 (0-End)
      • engineered (120)
      • engineered (143)
    Domains in SCOPe 2.08: d3kgpa_
  • Heterogens: 4AZ, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3kgpA (A:)
iiggefttienqpwfaaiyrrhrggsvtyvcggslispcwvisathcfidypkkedyivy
lgrsrlnsntqgemkfevenlilhkdysadtlahhndiallkirskegrcaqpsrtiqti
alpsmyndpqfgtsceitgfgkeqstdylypeqlkmtvvklishrecqqphyygsevttk
mlcaadpqwktdscqgdsggplvcslqgrmtltgivswgrgcalkdkpgvytrvshflpw
irshtkeenglal

    Sequence, based on observed residues (ATOM records): (download) 
    >3kgpA (A:)
iiggefttienqpwfaaiyrrhvtyvcggslispcwvisathcfidypkkedyivylgrs
rlnsntqgemkfevenlilhkdysadahhndiallkirskegrcaqpsrtiqtialpsmy
ndpqfgtsceitgfgkeqstdylypeqlkmtvvklishrecqqphyygsevttkmlcaad
pqwktdscqgdsggplvcslqgrmtltgivswgrgcalkdkpgvytrvshflpwirsht