Lineage for Protein: Glycogen synthase kinase-3 beta (Gsk3b)

  1. Root: SCOPe 2.08
  2. 2923792Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
  3. 2979545Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2979546Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2979693Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2981559Protein Glycogen synthase kinase-3 beta (Gsk3b) [69823] (2 species)
    CMGC group; GSK3 subfamily; serine/threonine kinase

Species:

  1. 2981560Human (Homo sapiens) [TaxId:9606] [69824] (57 PDB entries)
    Uniprot P49841 35-383 ! Uniprot P49841 35-384
    1. Domains for 1gng:
      1. 2981589Domain d1gnga_: 1gng A: [76239]
        complexed with so4, trs
      2. 2981590Domain d1gngb_: 1gng B: [76240]
        complexed with so4, trs
    2. Domains for 1h8f:
      1. 2981652Domain d1h8fa_: 1h8f A: [65733]
        complexed with epe
      2. 2981653Domain d1h8fb_: 1h8f B: [65734]
        complexed with epe
    3. Domains for 1i09:
      1. 2981619Domain d1i09a_: 1i09 A: [65976]
        complexed with po4
      2. 2981620Domain d1i09b_: 1i09 B: [65977]
        complexed with po4
    4. Domains for 1j1b:
      1. 2981561Domain d1j1ba_: 1j1b A: [90758]
        complexed with anp
      2. 2981562Domain d1j1bb_: 1j1b B: [90759]
        complexed with anp
    5. Domains for 1j1c:
      1. 2981568Domain d1j1ca_: 1j1c A: [90760]
        complexed with adp, mg
      2. 2981569Domain d1j1cb_: 1j1c B: [90761]
        complexed with adp, mg
    6. Domain for 1o9u:
      • 2981623Domain d1o9ua_: 1o9u A: [92691]
        complexed with axin peptide
        complexed with adz
    7. Domains for 1pyx:
      1. 2981581Domain d1pyxa_: 1pyx A: [95383]
        complexed with anp, mg
      2. 2981582Domain d1pyxb_: 1pyx B: [95384]
        complexed with anp, mg
    8. Domains for 1q3d:
      1. 2981571Domain d1q3da_: 1q3d A: [95667]
        complexed with stu
      2. 2981572Domain d1q3db_: 1q3d B: [95668]
        complexed with stu
    9. Domains for 1q3w:
      1. 2981583Domain d1q3wa_: 1q3w A: [95768]
        complexed with atu
      2. 2981584Domain d1q3wb_: 1q3w B: [95769]
        complexed with atu
    10. Domains for 1q41:
      1. 2981565Domain d1q41a_: 1q41 A: [95774]
        complexed with ixm
      2. 2981566Domain d1q41b_: 1q41 B: [95775]
        complexed with ixm
    11. Domains for 1q4l:
      1. 2981596Domain d1q4la_: 1q4l A: [95803]
        complexed with 679
      2. 2981597Domain d1q4lb_: 1q4l B: [95804]
        complexed with 679
    12. Domains for 1q5k:
      1. 2981563Domain d1q5ka_: 1q5k A: [104537]
        complexed with tmu
      2. 2981564Domain d1q5kb_: 1q5k B: [104538]
        complexed with tmu
    13. Domains for 1r0e:
      1. 2981577Domain d1r0ea_: 1r0e A: [111663]
        complexed with dfn, flc
      2. 2981578Domain d1r0eb_: 1r0e B: [111664]
        complexed with dfn, flc
    14. Domain for 1uv5:
    15. Domains for 2jld:
      1. 2981615Domain d2jlda_: 2jld A: [205109]
        automated match to d1j1ba_
        complexed with ag1
      2. 2981616Domain d2jldb_: 2jld B: [205110]
        automated match to d1j1ba_
        complexed with ag1
    16. Domain for 2o5k:
    17. Domains for 2ow3:
      1. 2981654Domain d2ow3a_: 2ow3 A: [149037]
        automated match to d1h8fa_
        complexed with bim
      2. 2981655Domain d2ow3b_: 2ow3 B: [149038]
        automated match to d1h8fa_
        complexed with bim
    18. Domains for 3du8:
      1. 2981598Domain d3du8a_: 3du8 A: [209307]
        automated match to d1pyxa_
        complexed with 553
      2. 2981599Domain d3du8b_: 3du8 B: [209308]
        automated match to d1pyxa_
        complexed with 553
    19. Domains for 3f7z:
      1. 2981626Domain d3f7za1: 3f7z A:35-383 [175555]
        Other proteins in same PDB: d3f7za2, d3f7zb2
        automated match to d1gngb_
        complexed with 34o
      2. 2981627Domain d3f7zb1: 3f7z B:35-383 [175556]
        Other proteins in same PDB: d3f7za2, d3f7zb2
        automated match to d1gngb_
        complexed with 34o
    20. Domains for 3f88:
      1. 2981644Domain d3f88a_: 3f88 A: [175562]
        automated match to d1gngb_
        complexed with 2ht, 3ht
      2. 2981645Domain d3f88b_: 3f88 B: [175563]
        automated match to d1gngb_
        complexed with 2ht, 3ht
    21. Domains for 3i4b:
      1. 2981611Domain d3i4ba_: 3i4b A: [211468]
        automated match to d1q5ka_
        complexed with z48
      2. 2981612Domain d3i4bb_: 3i4b B: [211469]
        automated match to d1q5ka_
        complexed with z48
    22. Domains for 3l1s:
      1. 2981656Domain d3l1sa_: 3l1s A: [232755]
        automated match to d3i4ba_
        complexed with po4, z92
      2. 2981657Domain d3l1sb_: 3l1s B: [232754]
        automated match to d1q5ka_
        complexed with po4, z92
    23. Domains for 3m1s:
      1. 2981605Domain d3m1sa_: 3m1s A: [247577]
        automated match to d1j1bb_
        complexed with dw1
      2. 2981606Domain d3m1sb_: 3m1s B: [247578]
        automated match to d1j1bb_
        complexed with dw1
    24. Domains for 3pup:
      1. 2981609Domain d3pupa_: 3pup A: [214950]
        automated match to d1j1ba_
        complexed with os1
      2. 2981610Domain d3pupb_: 3pup B: [214951]
        automated match to d1j1ba_
        complexed with os1
    25. Domains for 3q3b:
      1. 2981648Domain d3q3ba_: 3q3b A: [215051]
        automated match to d1q41a_
        complexed with 55e
      2. 2981649Domain d3q3bb_: 3q3b B: [215052]
        automated match to d1q41a_
        complexed with 55e
    26. Domains for 3say:
      1. 2981603Domain d3saya_: 3say A: [249327]
        automated match to d1j1bb_
        complexed with fmt, mla, mpd, oft
      2. 2981604Domain d3sayb_: 3say B: [249328]
        automated match to d1j1bb_
        complexed with fmt, mla, mpd, oft
    27. Domains for 3sd0:
      1. 2981591Domain d3sd0a_: 3sd0 A: [200612]
        automated match to d3sd0b_
        complexed with epe, tsk; mutant
      2. 2981592Domain d3sd0b_: 3sd0 B: [196271]
        automated match to d1gngb_
        complexed with epe, tsk; mutant
    28. Domains for 3zrk:
      1. 2981573Domain d3zrka_: 3zrk A: [186533]
        automated match to d1j1bb_
        complexed with gol, so4, zrk
      2. 2981574Domain d3zrkb_: 3zrk B: [186534]
        automated match to d1j1bb_
        complexed with gol, so4, zrk
    29. Domains for 3zrl:
      1. 2981575Domain d3zrla_: 3zrl A: [186535]
        automated match to d1j1bb_
        complexed with gol, so4, zrl
      2. 2981576Domain d3zrlb_: 3zrl B: [186536]
        automated match to d1j1bb_
        complexed with gol, so4, zrl
    30. Domains for 3zrm:
      1. 2981579Domain d3zrma_: 3zrm A: [186537]
        automated match to d1j1bb_
        complexed with gol, so4, zrm
      2. 2981580Domain d3zrmb_: 3zrm B: [186538]
        automated match to d1j1bb_
        complexed with gol, so4, zrm
    31. Domain for 4dit:
    32. Domains for 4iq6:
      1. 2981664Domain d4iq6a_: 4iq6 A: [252670]
        automated match to d1j1bb_
        complexed with iq6
      2. 2981665Domain d4iq6b_: 4iq6 B: [252671]
        automated match to d1j1bb_
        complexed with iq6
    33. Domains for 4j1r:
      1. 2981640Domain d4j1ra_: 4j1r A: [252802]
        automated match to d1j1bb_
        complexed with i5r, k, po4
      2. 2981641Domain d4j1rb_: 4j1r B: [252803]
        automated match to d1j1bb_
        complexed with i5r, k, po4
      3. 2981642Domain d4j1rc_: 4j1r C: [252804]
        automated match to d1j1bb_
        complexed with i5r, k, po4
      4. 2981643Domain d4j1rd_: 4j1r D: [252805]
        automated match to d1j1bb_
        complexed with i5r, k, po4
    34. Domains for 4j71:
      1. 2981613Domain d4j71a_: 4j71 A: [252833]
        automated match to d1j1bb_
        complexed with 1jx, cl, so4
      2. 2981614Domain d4j71b_: 4j71 B: [252834]
        automated match to d1j1bb_
        complexed with 1jx, cl, so4
    35. Domain for 4nm0:
    36. Domains for 4ptc:
      1. 2981650Domain d4ptca_: 4ptc A: [271216]
        automated match to d1j1bb_
        complexed with 2we
      2. 2981651Domain d4ptcb_: 4ptc B: [271215]
        automated match to d1j1bb_
        complexed with 2we
    37. Domains for 4pte:
      1. 2981585Domain d4ptea_: 4pte A: [271207]
        automated match to d1j1bb_
        complexed with 2wf
      2. 2981586Domain d4pteb_: 4pte B: [271208]
        automated match to d1j1bb_
        complexed with 2wf
    38. Domains for 4ptg:
      1. 2981617Domain d4ptga_: 4ptg A: [271206]
        automated match to d1j1bb_
        complexed with 2wg
      2. 2981618Domain d4ptgb_: 4ptg B: [271213]
        automated match to d1j1bb_
        complexed with 2wg
    39. Domains for 5f94:
      1. 2981630Domain d5f94a_: 5f94 A: [314291]
        automated match to d3zrla_
        complexed with 3uo
      2. 2981631Domain d5f94b_: 5f94 B: [314076]
        automated match to d3zrla_
        complexed with 3uo
    40. Domains for 5f95:
      1. 2981632Domain d5f95a_: 5f95 A: [314138]
        automated match to d3zrla_
        complexed with 3up
      2. 2981633Domain d5f95b_: 5f95 B: [314555]
        automated match to d3zrla_
        complexed with 3up
    41. Domains for 5hln:
      1. 2981662Domain d5hlna_: 5hln A: [317782]
        automated match to d1j1bb_
        complexed with 65c, mes, mg
      2. 2981663Domain d5hlnb_: 5hln B: [317787]
        automated match to d1j1bb_
        complexed with 65c, mes, mg
    42. Domains for 5hlp:
      1. 2981628Domain d5hlpa_: 5hlp A: [317763]
        automated match to d1j1bb_
        complexed with 65a
      2. 2981629Domain d5hlpb_: 5hlp B: [317788]
        automated match to d1j1bb_
        complexed with 65a
    43. Domains for 5k5n:
      1. 2981600Domain d5k5na_: 5k5n A: [323024]
        automated match to d1gngb_
        complexed with 6qh, so4
      2. 2981601Domain d5k5nb_: 5k5n B: [323049]
        automated match to d1gngb_
        complexed with 6qh, so4
    44. Domains for 5kpk:
      1. 2981624Domain d5kpka_: 5kpk A: [346580]
        automated match to d1j1bb_
        complexed with 6vk
      2. 2981625Domain d5kpkb_: 5kpk B: [346618]
        automated match to d1j1bb_
        complexed with 6vk
    45. Domains for 5kpl:
      1. 2981638Domain d5kpla_: 5kpl A: [346530]
        automated match to d1j1bb_
        complexed with 6vl
      2. 2981639Domain d5kplb_: 5kpl B: [346519]
        automated match to d1j1bb_
        complexed with 6vl
    46. Domains for 5kpm:
      1. 2981646Domain d5kpma_: 5kpm A: [346628]
        automated match to d1j1bb_
        complexed with 6vm
      2. 2981647Domain d5kpmb_: 5kpm B: [346521]
        automated match to d1j1bb_
        complexed with 6vm
    47. Domains for 6gjo:
      1. 2981659Domain d6gjoa_: 6gjo A: [366849]
        automated match to d1q5ka_
        complexed with f1b
      2. 2981660Domain d6gjob_: 6gjo B: [366842]
        automated match to d1q5ka_
        complexed with f1b
    48. Domains for 6gn1:
      1. 2981634Domain d6gn1a_: 6gn1 A: [353694]
        automated match to d1j1bb_
        complexed with cl, f4n
      2. 2981635Domain d6gn1b_: 6gn1 B: [353713]
        automated match to d1j1bb_
        complexed with cl, f4n
    49. Domains for 6h0u:
      1. 2981607Domain d6h0ua_: 6h0u A: [368834]
        automated match to d1j1ba_
        complexed with cl, fkb, gol, mli, na
      2. 2981608Domain d6h0ub_: 6h0u B: [368894]
        automated match to d1j1ba_
        complexed with cl, fkb, gol, mli, na
    50. Domains for 6hk3:
      1. 2981621Domain d6hk3a_: 6hk3 A: [370286]
        automated match to d1gngb_
        complexed with cl, dms, g8b, gol, mli
      2. 2981622Domain d6hk3b_: 6hk3 B: [370295]
        automated match to d1gngb_
        complexed with cl, dms, g8b, gol, mli
    51. Domains for 6hk4:
      1. 2981636Domain d6hk4a_: 6hk4 A: [370248]
        automated match to d1gngb_
        complexed with dms, g8e, gol, mli
      2. 2981637Domain d6hk4b_: 6hk4 B: [370256]
        automated match to d1gngb_
        complexed with dms, g8e, gol, mli
    52. Domain for 6tcu:
    53. Domain for 6v6l:
    54. Domain for 6y9r:
    55. Domains for 6y9s:
      1. 2981587Domain d6y9sa_: 6y9s A: [386073]
        automated match to d1gngb_
        complexed with act, ohk
      2. 2981588Domain d6y9sb_: 6y9s B: [386017]
        automated match to d1gngb_
        complexed with act, ohk
    56. Domain for 7b6f:
    57. Domains for 7u36:
      1. 3086368Domain d7u36a_: 7u36 A: [422685]
        automated match to d1h8fa_
        complexed with cl, l7w
      2. 3086401Domain d7u36b_: 7u36 B: [422718]
        automated match to d1h8fa_
        complexed with cl, l7w
  2. 2981666Mouse (Mus musculus) [TaxId:10090] [357651] (1 PDB entry)

More info for Protein Glycogen synthase kinase-3 beta (Gsk3b) from d.144.1.7: Protein kinases, catalytic subunit

Timeline for Protein Glycogen synthase kinase-3 beta (Gsk3b) from d.144.1.7: Protein kinases, catalytic subunit: