PDB entry 5hlp

View 5hlp on RCSB PDB site
Description: x-ray crystal structure of gsk3b in complex with brd3937
Class: transferase/transferase inhibitor
Keywords: Protein kinase, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2016-01-15, released 2016-05-25
The last revision prior to the SCOPe 2.08 freeze date was dated 2016-07-27, with a file datestamp of 2016-07-22.
Experiment type: XRAY
Resolution: 2.45 Å
R-factor: N/A
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Glycogen synthase kinase-3 beta
    Species: Homo sapiens [TaxId:9606]
    Gene: GSK3B
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5hlpa_
  • Chain 'B':
    Compound: Glycogen synthase kinase-3 beta
    Species: Homo sapiens [TaxId:9606]
    Gene: GSK3B
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5hlpb_
  • Heterogens: 65A, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5hlpA (A:)
gspgmsgrprttsfaesckpvqqpsafgsmkvsrdkdgskvttvvatpgqgpdrpqevsy
tdtkvigngsfgvvyqaklcdsgelvaikkvlqdkrfknrelqimrkldhcnivrlryff
yssgekkdevylnlvldyvpetvyrvarhysrakqtlpviyvklymyqlfrslayihsfg
ichrdikpqnllldpdtavlklcdfgsakqlvrgepnvsyicsryyrapelifgatdyts
sidvwsagcvlaelllgqpifpgdsgvdqlveiikvlgtptreqiremnpnytefkfpqi
kahpwtkvfrprtppeaialcsrlleytptarltpleacahsffdelrdpnvklpngrdt
palfnfttqelssnpplatilipphariqaaastptnataasdantgdrgqtnnaasasa
snst

    Sequence, based on observed residues (ATOM records): (download) 
    >5hlpA (A:)
kvttvvatpgqgpdrpqevsytdtkvigngsfgvvyqaklcdsgelvaikkvlqdkrfkn
relqimrkldhcnivrlryffyssevylnlvldyvpetvyrvarhysrakqtlpviyvkl
ymyqlfrslayihsfgichrdikpqnllldpdtavlklcdfgsakqlvrgepnvsyicsr
yyrapelifgatdytssidvwsagcvlaelllgqpifpgdsgvdqlveiikvlgtptreq
iremnpnfkfpqikahpwtkvfrprtppeaialcsrlleytptarltpleacahsffdel
rdpnvklpngrdtpalfnfttqelssnpplatilippha

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5hlpB (B:)
gspgmsgrprttsfaesckpvqqpsafgsmkvsrdkdgskvttvvatpgqgpdrpqevsy
tdtkvigngsfgvvyqaklcdsgelvaikkvlqdkrfknrelqimrkldhcnivrlryff
yssgekkdevylnlvldyvpetvyrvarhysrakqtlpviyvklymyqlfrslayihsfg
ichrdikpqnllldpdtavlklcdfgsakqlvrgepnvsyicsryyrapelifgatdyts
sidvwsagcvlaelllgqpifpgdsgvdqlveiikvlgtptreqiremnpnytefkfpqi
kahpwtkvfrprtppeaialcsrlleytptarltpleacahsffdelrdpnvklpngrdt
palfnfttqelssnpplatilipphariqaaastptnataasdantgdrgqtnnaasasa
snst

    Sequence, based on observed residues (ATOM records): (download) 
    >5hlpB (B:)
kvttvvatpgqgpdrpqevsytdtkvigngsfgvvyqaklcdsgelvaikkvlqdkrfkn
relqimrkldhcnivrlryffyssevylnlvldyvpetvyrvarhysrakqtlpviyvkl
ymyqlfrslayihsfgichrdikpqnllldpdtavlklcdfgsakqlvrgepnvsyicsr
yyrapelifgatdytssidvwsagcvlaelllgqpifpgdsgvdqlveiikvlgtptreq
iremnpnpqikahpwtkvfrprtppeaialcsrlleytptarltpleacahsffdelrdp
nvklpngrdtpalfnfttqelssnpplatilipphar