Lineage for d6hk4a_ (6hk4 A:)

  1. Root: SCOPe 2.07
  2. 2494617Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2542179Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2542180Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2542316Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2543788Protein Glycogen synthase kinase-3 beta (Gsk3b) [69823] (2 species)
    CMGC group; GSK3 subfamily; serine/threonine kinase
  7. 2543789Species Human (Homo sapiens) [TaxId:9606] [69824] (56 PDB entries)
    Uniprot P49841 35-383 ! Uniprot P49841 35-384
  8. 3070186Domain d6hk4a_: 6hk4 A: [370248]
    automated match to d1gngb_
    complexed with dms, g8e, gol, mli

Details for d6hk4a_

PDB Entry: 6hk4 (more details), 2.5 Å

PDB Description: crystal structure of gsk-3b in complex with pyrazine inhibitor c22
PDB Compounds: (A:) Glycogen synthase kinase-3 beta

SCOPe Domain Sequences for d6hk4a_:

Sequence; same for both SEQRES and ATOM records: (download)

>d6hk4a_ d.144.1.7 (A:) Glycogen synthase kinase-3 beta (Gsk3b) {Human (Homo sapiens) [TaxId: 9606]}
skvttvvatpgqgpdrpqevsytdtkvigngsfgvvyqaklcdsgelvaikkvlqdkrfk
nrelqimrkldhcnivrlryffyssgekkdevylnlvldyvpetvyrvarhysrakqtlp
viyvklymyqlfrslayihsfgichrdikpqnllldpdtavlklcdfgsakqlvrgepnv
syicsryyrapelifgatdytssidvwsagcvlaelllgqpifpgdsgvdqlveiikvlg
tptreqiremnpnytefkfpqikahpwtkvfrprtppeaialcsrlleytptarltplea
cahsffdelrdpnvklpngrdtpalfnfttqelssnpplatilipphari

SCOPe Domain Coordinates for d6hk4a_:

Click to download the PDB-style file with coordinates for d6hk4a_.
(The format of our PDB-style files is described here.)

Timeline for d6hk4a_:

  • d6hk4a_ is new in SCOPe 2.07-stable