PDB entry 7b6f

View 7b6f on RCSB PDB site
Description: GSK3-beta in complex with compound (S)-5c
Class: transferase
Keywords: kinase inhibitors, structure-based drug design, GSK3-beta inhibitor, Structural Genomics Consortium, SGC, transferase
Deposited on 2020-12-07, released 2020-12-16
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-12-16, with a file datestamp of 2020-12-11.
Experiment type: XRAY
Resolution: 2.05 Å
R-factor: N/A
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Glycogen synthase kinase-3 beta
    Species: Homo sapiens [TaxId:9606]
    Gene: GSK3B
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7b6fa_
  • Heterogens: SZW, EDO, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7b6fA (A:)
mkvsrdkdgskvttvvatpgqgpdrpqevsytdtkvigngsfgvvyqaklcdsgelvaik
kvlqdkrfknrelqimrkldhcnivrlryffyssgekkdevylnlvldyvpetvyrvarh
ysrakqtlpviyvklymyqlfrslayihsfgichrdikpqnllldpdtavlklcdfgsak
qlvrgepnvsyicsryyrapelifgatdytssidvwsagcvlaelllgqpifpgdsgvdq
lveiikvlgtptreqiremnpnytefkfpqikahpwtkvfrprtppeaialcsrlleytp
tarltpleacahsffdelrdpnvklpngrdtpalfnfttqelssnpplatilippharah
hhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >7b6fA (A:)
kvttvvatpgqgpdrpqevsytdtkvigngsfgvvyqaklcdsgelvaikkvlqdkrfkn
relqimrkldhcnivrlryffyssgekkdevylnlvldyvpetvyrvarhysrakqtlpv
iyvklymyqlfrslayihsfgichrdikpqnllldpdtavlklcdfgsakqlvrgepnvs
yicsryyrapelifgatdytssidvwsagcvlaelllgqpifpgdsgvdqlveiikvlgt
ptreqiremnpnytefkfpqikahpwtkvfrprtppeaialcsrlleytptarltpleac
ahsffdelrdpnvklpngrdtpalfnfttqelssnpplatilippha