PDB entry 6hk3
View 6hk3 on RCSB PDB site
Description: Crystal structure of GSK-3B in complex with pyrazine inhibitor C44
Class: transferase
Keywords: GSK 3B, Complex, pyrazine, inhibitor, transferase
Deposited on
2018-09-05, released
2019-07-17
The last revision prior to the SCOPe 2.08 freeze date was dated
2019-08-21, with a file datestamp of
2019-08-16.
Experiment type: XRAY
Resolution: 2.35 Å
R-factor: N/A
AEROSPACI score: 0.23
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Glycogen synthase kinase-3 beta
Species: Homo sapiens [TaxId:9606]
Gene: GSK3B
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d6hk3a_ - Chain 'B':
Compound: Glycogen synthase kinase-3 beta
Species: Homo sapiens [TaxId:9606]
Gene: GSK3B
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d6hk3b_ - Chain 'N':
Compound: gly-ser-his-gly-his-his-his-his
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Heterogens: G8B, MLI, GOL, CL, DMS, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>6hk3A (A:)
skvttvvatpgqgpdrpqevsytdtkvigngsfgvvyqaklcdsgelvaikkvlqdkrfk
nrelqimrkldhcnivrlryffyssgekkdevylnlvldyvpetvyrvarhysrakqtlp
viyvklymyqlfrslayihsfgichrdikpqnllldpdtavlklcdfgsakqlvrgepnv
syicsryyrapelifgatdytssidvwsagcvlaelllgqpifpgdsgvdqlveiikvlg
tptreqiremnpnytefkfpqikahpwtkvfrprtppeaialcsrlleytptarltplea
cahsffdelrdpnvklpngrdtpalfnfttqelssnpplatilipphari
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>6hk3B (B:)
skvttvvatpgqgpdrpqevsytdtkvigngsfgvvyqaklcdsgelvaikkvlqdkrfk
nrelqimrkldhcnivrlryffyssgekkdevylnlvldyvpetvyrvarhysrakqtlp
viyvklymyqlfrslayihsfgichrdikpqnllldpdtavlklcdfgsakqlvrgepnv
syicsryyrapelifgatdytssidvwsagcvlaelllgqpifpgdsgvdqlveiikvlg
tptreqiremnpnytefkfpqikahpwtkvfrprtppeaialcsrlleytptarltplea
cahsffdelrdpnvklpngrdtpalfnfttqelssnpplatilipphari
- Chain 'N':
No sequence available.