SCOPe 2.08: Protein: c-src tyrosine kinase

Lineage for Protein: c-src tyrosine kinase

Root: SCOPe 2.08
Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
Fold d.93: SH2-like [55549] (1 superfamily)
3 layers: a/b/a; antiparallel beta-sheet of 5 strands is flanked by two helices
Superfamily d.93.1: SH2 domain [55550] (2 families)
Family d.93.1.1: SH2 domain [55551] (35 proteins)
Pfam PF00017
Protein c-src tyrosine kinase [55556] (4 species)

Species:

Chicken (Gallus gallus) [TaxId:9031] [55558] (4 PDB entries)
1. Domain for 1f1w:
  - Domain d1f1wa_: 1f1w A: [40456]
    mutant
2. Domain for 1f2f:
  - Domain d1f2fa_: 1f2f A: [40455]
    complexed with po4; mutant
3. Domains for 1p13:
  1. Domain d1p13a_: 1p13 A: [93892]
    complexed with peptide, chains C and D
    complexed with cac
  2. Domain d1p13b_: 1p13 B: [93893]
    complexed with peptide, chains C and D
    complexed with cac
4. Domain for 2ptk:
  - Domain d2ptka2: 2ptk A:146-248 [40457]
    Other proteins in same PDB: d2ptka1, d2ptka3, d2ptka4
Human (Homo sapiens) [TaxId:9606] [55557] (46 PDB entries)
1. Domains for 1a07:
  1. Domain d1a07a_: 1a07 A: [40443]
  2. Domain d1a07b_: 1a07 B: [40444]
2. Domains for 1a08:
  1. Domain d1a08a_: 1a08 A: [40447]
  2. Domain d1a08b_: 1a08 B: [40448]
3. Domains for 1a09:
  1. Domain d1a09a_: 1a09 A: [40438]
  2. Domain d1a09b_: 1a09 B: [40439]
4. Domains for 1a1a:
  1. Domain d1a1aa_: 1a1a A: [40449]
    mutant
  2. Domain d1a1ab_: 1a1a B: [40450]
    mutant
5. Domains for 1a1b:
  1. Domain d1a1ba_: 1a1b A: [40441]
  2. Domain d1a1bb_: 1a1b B: [40442]
6. Domains for 1a1c:
  1. Domain d1a1ca_: 1a1c A: [40451]
  2. Domain d1a1cb_: 1a1c B: [40452]
7. Domains for 1a1e:
  1. Domain d1a1ea_: 1a1e A: [40445]
  2. Domain d1a1eb_: 1a1e B: [40446]
8. Domain for 1fmk:
  - Domain d1fmka2: 1fmk A:146-248 [40436]
    Other proteins in same PDB: d1fmka1, d1fmka3
9. Domain for 1hcs:
  - Domain d1hcsb_: 1hcs B: [40453]
10. Domain for 1hct:
  - Domain d1hctb_: 1hct B: [40454]
11. Domain for 1ksw:
  - Domain d1kswa2: 1ksw A:146-248 [68861]
    Other proteins in same PDB: d1kswa1, d1kswa3
    complexed with nbs; mutant
12. Domain for 1o41:
  - Domain d1o41a_: 1o41 A: [92443]
    complexed with 300
13. Domain for 1o42:
  - Domain d1o42a_: 1o42 A: [92444]
    complexed with 843
14. Domain for 1o43:
  - Domain d1o43a_: 1o43 A: [92445]
    complexed with 821
15. Domain for 1o44:
  - Domain d1o44a_: 1o44 A: [92446]
    complexed with 852
16. Domain for 1o45:
  - Domain d1o45a_: 1o45 A: [92447]
    complexed with 687
17. Domain for 1o46:
  - Domain d1o46a_: 1o46 A: [92448]
    complexed with 903
18. Domain for 1o47:
  - Domain d1o47a_: 1o47 A: [92449]
    complexed with 822
19. Domain for 1o48:
  - Domain d1o48a_: 1o48 A: [92450]
    complexed with 853
20. Domain for 1o49:
  - Domain d1o49a_: 1o49 A: [92451]
    complexed with 493
21. Domain for 1o4a:
  - Domain d1o4aa_: 1o4a A: [92452]
    complexed with 197
22. Domain for 1o4b:
  - Domain d1o4ba_: 1o4b A: [92453]
    complexed with 876
23. Domain for 1o4c:
  - Domain d1o4ca_: 1o4c A: [92454]
    complexed with po4
24. Domain for 1o4d:
  - Domain d1o4da_: 1o4d A: [92455]
    complexed with 262
25. Domain for 1o4e:
  - Domain d1o4ea_: 1o4e A: [92456]
    complexed with 299
26. Domain for 1o4f:
  - Domain d1o4fa_: 1o4f A: [92457]
    complexed with 790
27. Domain for 1o4g:
  - Domain d1o4ga_: 1o4g A: [92458]
    complexed with i59
28. Domain for 1o4h:
  - Domain d1o4ha_: 1o4h A: [92459]
    complexed with 772
29. Domain for 1o4i:
  - Domain d1o4ia_: 1o4i A: [92460]
    complexed with 219
30. Domain for 1o4j:
  - Domain d1o4ja_: 1o4j A: [92461]
    complexed with is2
31. Domain for 1o4k:
  - Domain d1o4ka_: 1o4k A: [92462]
    complexed with psn
32. Domain for 1o4l:
  - Domain d1o4la_: 1o4l A: [92463]
    complexed with cit
33. Domain for 1o4m:
  - Domain d1o4ma_: 1o4m A: [92464]
    complexed with mla
34. Domain for 1o4n:
  - Domain d1o4na_: 1o4n A: [92465]
    complexed with oxd
35. Domain for 1o4o:
  - Domain d1o4oa_: 1o4o A: [92466]
    complexed with hps
36. Domain for 1o4p:
  - Domain d1o4pa_: 1o4p A: [92467]
    complexed with 791
37. Domain for 1o4q:
  - Domain d1o4qa_: 1o4q A: [92468]
    complexed with 256
38. Domain for 1o4r:
  - Domain d1o4ra_: 1o4r A: [92469]
    complexed with 787
39. Domain for 1shd:
  - Domain d1shda_: 1shd A: [40440]
40. Domain for 1y57:
  - Domain d1y57a2: 1y57 A:146-248 [145904]
    Other proteins in same PDB: d1y57a1, d1y57a3, d1y57a4
    automated match to d1fmka2
    complexed with mpz, so4
41. Domain for 2h8h:
  - Domain d2h8ha2: 2h8h A:146-248 [147241]
    Other proteins in same PDB: d2h8ha1, d2h8ha3, d2h8ha4
    automated match to d1fmka2
    complexed with h8h
42. Domain for 2src:
  - Domain d2srca2: 2src A:146-248 [40437]
    Other proteins in same PDB: d2srca1, d2srca3
    complexed with anp
43. Domain for 4f59:
  - Domain d4f59a_: 4f59 A: [221036]
    automated match to d4f5aa_
    mutant
44. Domain for 4f5a:
  - Domain d4f5aa_: 4f5a A: [193481]
    automated match to d1hcsb_
    complexed with po4; mutant
45. Domain for 4f5b:
  - Domain d4f5ba_: 4f5b A: [221037]
    automated match to d4f5aa_
    complexed with ptr; mutant
46. Domain for 4k11:
  - Domain d4k11a2: 4k11 A:146-248 [253133]
    Other proteins in same PDB: d4k11a1, d4k11a3
    automated match to d1fmka2
    complexed with 0j9
Mouse (Mus musculus) [TaxId:10090] [350470] (1 PDB entry)
- Domain for 6f3f:
  - Domain d6f3fa2: 6f3f A:146-248 [350471]
    Other proteins in same PDB: d6f3fa1, d6f3fa3, d6f3fa4
    automated match to d1fmka2
    complexed with adp, mg
Rous sarcoma virus [TaxId:11886] [69782] (12 PDB entries)
1. Domain for 1bkl:
  - Domain d1bkla1: 1bkl A:3-106 [40428]
    Other proteins in same PDB: d1bkla2
2. Domain for 1bkm:
  - Domain d1bkma_: 1bkm A: [40426]
    complexed with 1c5
3. Domains for 1is0:
  1. Domain d1is0a_: 1is0 A: [66299]
  2. Domain d1is0b_: 1is0 B: [66300]
4. Domain for 1kc2:
  - Domain d1kc2a_: 1kc2 A: [72291]
    complexed with co; mutant
5. Domains for 1nzl:
  1. Domain d1nzla_: 1nzl A: [86453]
    complexed with doubly phosphorylated peptide, chain C
    complexed with cl, pg4
  2. Domain d1nzlb_: 1nzl B: [86454]
    complexed with doubly phosphorylated peptide, chain C
    complexed with cl, pg4
6. Domains for 1nzv:
  1. Domain d1nzva_: 1nzv A: [86457]
    complexed with doubly phosphorylated peptide, chain C
    complexed with cl, pg4
  2. Domain d1nzvb_: 1nzv B: [86458]
    complexed with doubly phosphorylated peptide, chain C
    complexed with cl, pg4
7. Domain for 1sha:
  - Domain d1shaa_: 1sha A: [40424]
8. Domain for 1shb:
  - Domain d1shba_: 1shb A: [40425]
9. Domain for 1skj:
  - Domain d1skja_: 1skj A: [40427]
    complexed with ur2
10. Domains for 1spr:
  1. Domain d1spra_: 1spr A: [40429]
    complexed with po4
  2. Domain d1sprb_: 1spr B: [40430]
    complexed with po4
  3. Domain d1sprc_: 1spr C: [40431]
    complexed with po4
  4. Domain d1sprd_: 1spr D: [40432]
    complexed with po4
11. Domains for 1sps:
  1. Domain d1spsa_: 1sps A: [40433]
  2. Domain d1spsb_: 1sps B: [40434]
  3. Domain d1spsc_: 1sps C: [40435]
12. Domain for 2jyq:
  - Domain d2jyqa_: 2jyq A: [148242]
    automated match to d1aotf_

More info for Protein c-src tyrosine kinase from d.93.1.1: SH2 domain

Timeline for Protein c-src tyrosine kinase from d.93.1.1: SH2 domain:

Protein c-src tyrosine kinase from d.93.1.1: SH2 domain first appeared (with stable ids) in SCOP 1.55
Protein c-src tyrosine kinase from d.93.1.1: SH2 domain appears in SCOPe 2.07