SCOPe 2.08: Domain d1nzla_: 1nzl A:

Lineage for d1nzla_ (1nzl A:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.93: SH2-like [55549] (1 superfamily)
   3 layers: a/b/a; antiparallel beta-sheet of 5 strands is flanked by two helices

4. Superfamily d.93.1: SH2 domain [55550] (2 families)

5. Family d.93.1.1: SH2 domain [55551] (35 proteins)
   Pfam PF00017

6. Protein c-src tyrosine kinase [55556] (4 species)

7. Species Rous sarcoma virus [TaxId:11886] [69782] (12 PDB entries)

8. Domain d1nzla_: 1nzl A: [86453]
   complexed with doubly phosphorylated peptide, chain C
   complexed with cl, pg4

Details for d1nzla_

PDB Entry: 1nzl, 1.9 Å

PDB Description: Crystal Structure of Src SH2 domain bound to doubly phosphorylated peptide PQpYEpYIPI

PDB Compounds: (A:) Tyrosine-protein kinase transforming protein Src

SCOPe Domain Sequences for d1nzla_:

Sequence, based on SEQRES records:

>d1nzla_ d.93.1.1 (A:) c-src tyrosine kinase {Rous sarcoma virus [TaxId: 11886]}
aeewyfgkitrreserlllnpenprgtflvresettkgayclsvsdfdnakglnvkhyki
rkldsggfyitsrtqfsslqqlvayyskhadglchrltnvcpt

Sequence, based on observed residues (ATOM records):

>d1nzla_ d.93.1.1 (A:) c-src tyrosine kinase {Rous sarcoma virus [TaxId: 11886]}
aeewyfgkitrreserlllnpenprgtflvresetgayclsvsdfdnakglnvkhykirk
ldsggfyitsrtqfsslqqlvayyskhadglchrltnvcpt

Timeline for d1nzla_:

• d1nzla_ first appeared in SCOP 1.65
  
• d1nzla_ appears in SCOPe 2.07