PDB entry 2h8h

View 2h8h on RCSB PDB site
Description: Src kinase in complex with a quinazoline inhibitor
Class: transferase
Keywords: src kinase, transferase
Deposited on 2006-06-07, released 2006-11-21
The last revision prior to the SCOPe 2.08 freeze date was dated 2015-07-01, with a file datestamp of 2015-06-26.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Proto-oncogene tyrosine-protein kinase Src
    Species: Homo sapiens [TaxId:9606]
    Gene: SRC, SRC1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2h8ha1, d2h8ha2, d2h8ha3, d2h8ha4
  • Heterogens: H8H, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2h8hA (A:)
gsnkskpkdasqrrrslepaenvhgagggafpasqtpskpasadghrgpsaafapaaaep
klfggfnssdtvtspqragplaggvttfvalydyesrtetdlsfkkgerlqivnntegdw
wlahslstgqtgyipsnyvapsdsiqaeewyfgkitrreserlllnaenprgtflvrese
ttkgayclsvsdfdnakglnvkhykirkldsggfyitsrtqfnslqqlvayyskhadglc
hrlttvcptskpqtqglakdaweipreslrlevklgqgcfgevwmgtwngttrvaiktlk
pgtmspeaflqeaqvmkklrheklvqlyavvseepiyivteymskgslldflkgetgkyl
rlpqlvdmaaqiasgmayvermnyvhrdlraanilvgenlvckvadfglarliedneyta
rqgakfpikwtapeaalygrftiksdvwsfgilltelttkgrvpypgmvnrevldqverg
yrmpcppecpeslhdlmcqcwrkepeerptfeylqafledyftstepqyqpgenl

    Sequence, based on observed residues (ATOM records): (download) 
    >2h8hA (A:)
tfvalydyesrtetdlsfkkgerlqivnntegdwwlahslstgqtgyipsnyvapsdsiq
aeewyfgkitrreserlllnaenprgtflvresettkgayclsvsdfdnakglnvkhyki
rkldsggfyitsrtqfnslqqlvayyskhadglchrlttvcptskpqtqglakdaweipr
eslrlevklgqgcfgevwmgtwngttrvaiktlkpgtmspeaflqeaqvmkklrheklvq
lyavvseepiyivteymskgslldflkgetgkylrlpqlvdmaaqiasgmayvermnyvh
rdlraanilvgenlvckvadfglarliedneytarqgakfpikwtapeaalygrftiksd
vwsfgilltelttkgrvpypgmvnrevldqvergyrmpcppecpeslhdlmcqcwrkepe
erptfeylqafledyftstepqyqp