PDB entry 1spr

View 1spr on RCSB PDB site
Description: binding of a high affinity phosphotyrosyl peptide to the src sh2 domain: crystal structures of the complexed and peptide-free forms
Class: transferase(phosphotransferase)
Keywords: transferase(phosphotransferase)
Deposited on 1993-03-05, released 1994-05-31
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.185
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: src tyrosine kinase sh2 domain
    Species: Rous sarcoma virus [TaxId:11886]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1spra_
  • Chain 'B':
    Compound: src tyrosine kinase sh2 domain
    Species: Rous sarcoma virus [TaxId:11886]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1sprb_
  • Chain 'C':
    Compound: src tyrosine kinase sh2 domain
    Species: Rous sarcoma virus [TaxId:11886]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1sprc_
  • Chain 'D':
    Compound: src tyrosine kinase sh2 domain
    Species: Rous sarcoma virus [TaxId:11886]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1sprd_
  • Heterogens: PO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1sprA (A:)
qaeewyfgkitrreserlllnpenprgtflvresettkgayclsvsdfdnakglnvkhyk
irkldsggfyitsrtqfsslqqlvayyskhadglchrltnvcpt

    Sequence, based on observed residues (ATOM records): (download) 
    >1sprA (A:)
aeewyfgkitrreserlllnpenprgtflvresettkgayclsvsdfdnakglnvkhyki
rkldsggfyitsrtqfsslqqlvayyskhadglchrltnvcpt

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1sprB (B:)
qaeewyfgkitrreserlllnpenprgtflvresettkgayclsvsdfdnakglnvkhyk
irkldsggfyitsrtqfsslqqlvayyskhadglchrltnvcpt

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1sprC (C:)
qaeewyfgkitrreserlllnpenprgtflvresettkgayclsvsdfdnakglnvkhyk
irkldsggfyitsrtqfsslqqlvayyskhadglchrltnvcpt

    Sequence, based on observed residues (ATOM records): (download) 
    >1sprC (C:)
aeewyfgkitrreserlllnpenprgtflvresettkgayclsvsdfdnakglnvkhyki
rkldsggfyitsrtqfsslqqlvayyskhadglchrltnvcpt

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1sprD (D:)
qaeewyfgkitrreserlllnpenprgtflvresettkgayclsvsdfdnakglnvkhyk
irkldsggfyitsrtqfsslqqlvayyskhadglchrltnvcpt

    Sequence, based on observed residues (ATOM records): (download) 
    >1sprD (D:)
aeewyfgkitrreserlllnpenprgtflvresettkgayclsvsdfdnakglnvkhyki
rkldsggfyitsrtqfsslqqlvayyskhadglchrltnvcpt