SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for Protein: p50 subunit of NF-kappa B transcription factor

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2017115Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 2032114Superfamily b.1.18: E set domains [81296] (24 families) (S)
    "Early" Ig-like fold families possibly related to the immunoglobulin and/or fibronectin type III superfamilies
  5. 2032115Family b.1.18.1: NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain [81279] (8 protein domains)
    subgroup of the larger IPT/TIG domain family
  6. 2032129Protein p50 subunit of NF-kappa B transcription factor [49248] (2 species)

Species:

  1. 2032130Human (Homo sapiens) [TaxId:9606] [49249] (3 PDB entries)
    Uniprot P25799 245-350
    1. Domains for 1nfi:
      1. 2032132Domain d1nfib_: 1nfi B: [21925]
        Other proteins in same PDB: d1nfia1, d1nfia2, d1nfic1, d1nfic2, d1nfie_, d1nfif_
      2. 2032133Domain d1nfid_: 1nfi D: [21926]
        Other proteins in same PDB: d1nfia1, d1nfia2, d1nfic1, d1nfic2, d1nfie_, d1nfif_
    2. Domain for 1svc:
    3. Domain for 2o61:
  2. 2032135Mouse (Mus musculus) [TaxId:10090] [49250] (15 PDB entries)
    1. Domain for 1bfs:
    2. Domain for 1ikn:
    3. Domains for 1le5:
      1. 2032154Domain d1le5b1: 1le5 B:251-350 [84585]
        Other proteins in same PDB: d1le5a1, d1le5a2, d1le5a3, d1le5b2, d1le5e1, d1le5e2, d1le5e3, d1le5f2
        protein/DNA complex
      2. 2032155Domain d1le5f1: 1le5 F:251-350 [84589]
        Other proteins in same PDB: d1le5a1, d1le5a2, d1le5a3, d1le5b2, d1le5e1, d1le5e2, d1le5e3, d1le5f2
        protein/DNA complex
    4. Domains for 1le9:
      1. 2032156Domain d1le9b1: 1le9 B:251-350 [84593]
        Other proteins in same PDB: d1le9a1, d1le9a2, d1le9a3, d1le9b2, d1le9e1, d1le9e2, d1le9e3, d1le9f2
        protein/DNA complex
      2. 2032157Domain d1le9f1: 1le9 F:251-350 [84597]
        Other proteins in same PDB: d1le9a1, d1le9a2, d1le9a3, d1le9b2, d1le9e1, d1le9e2, d1le9e3, d1le9f2
        protein/DNA complex
    5. Domain for 1lei:
    6. Domains for 1nfk:
      1. 2032148Domain d1nfka1: 1nfk A:251-350 [21929]
        Other proteins in same PDB: d1nfka2, d1nfkb2
        protein/DNA complex
      2. 2032149Domain d1nfkb1: 1nfk B:251-350 [21930]
        Other proteins in same PDB: d1nfka2, d1nfkb2
        protein/DNA complex
    7. Domains for 1ooa:
      1. 2032145Domain d1ooaa1: 1ooa A:251-350 [87192]
        Other proteins in same PDB: d1ooaa2, d1ooaa3, d1ooab2, d1ooab3
        protein/RNA complex
      2. 2032146Domain d1ooab1: 1ooa B:251-350 [87194]
        Other proteins in same PDB: d1ooaa2, d1ooaa3, d1ooab2, d1ooab3
        protein/RNA complex
    8. Domain for 1u36:
    9. Domain for 1u3j:
    10. Domain for 1u3y:
    11. Domain for 1u3z:
    12. Domains for 1u41:
      1. 2032140Domain d1u41a_: 1u41 A: [107648]
        mutant
      2. 2032141Domain d1u41b_: 1u41 B: [107649]
        mutant
      3. 2032142Domain d1u41c_: 1u41 C: [107650]
        mutant
      4. 2032143Domain d1u41d_: 1u41 D: [107651]
        mutant
    13. Domain for 1u42:
    14. Domain for 1vkx:
    15. Domain for 2i9t:

More info for Protein p50 subunit of NF-kappa B transcription factor from b.1.18.1: NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain

Timeline for Protein p50 subunit of NF-kappa B transcription factor from b.1.18.1: NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain: