PDB entry 1le9

View 1le9 on RCSB PDB site
Description: Crystal structure of a NF-kB heterodimer bound to the Ig/HIV-kB siti
Class: transcription/DNA
Keywords: transcription factor, NF-kB-DNA complex, TRANSCRIPTION-DNA COMPLEX
Deposited on 2002-04-09, released 2003-04-15
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-01-31, with a file datestamp of 2018-01-26.
Experiment type: XRAY
Resolution: 3 Å
R-factor: N/A
AEROSPACI score: 0.11 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: nuclear factor nf-kappa-b p65 subunit
    Species: Mus musculus [TaxId:10090]
    Gene: rela
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q04207 (2-273)
      • cloning artifact (1)
    Domains in SCOPe 2.08: d1le9a1, d1le9a2, d1le9a3
  • Chain 'B':
    Compound: nuclear factor nf-kappa-b p50 subunit
    Species: Mus musculus [TaxId:10090]
    Gene: NFKB1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1le9b1, d1le9b2
  • Chain 'C':
    Compound: 5'-d(*tp*gp*gp*gp*ap*cp*tp*tp*tp*cp*cp*t)-3'
  • Chain 'D':
    Compound: 5'-d(*ap*ap*gp*gp*ap*ap*ap*gp*tp*cp*cp*c)-3'
  • Chain 'E':
    Compound: nuclear factor nf-kappa-b p65 subunit
    Species: Mus musculus [TaxId:10090]
    Gene: rela
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q04207 (2-273)
      • cloning artifact (1)
    Domains in SCOPe 2.08: d1le9e1, d1le9e2, d1le9e3
  • Chain 'F':
    Compound: nuclear factor nf-kappa-b p50 subunit
    Species: Mus musculus [TaxId:10090]
    Gene: NFKB1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1le9f1, d1le9f2
  • Chain 'G':
    Compound: 5'-d(*tp*gp*gp*gp*ap*cp*tp*tp*tp*cp*cp*t)-3'
  • Chain 'H':
    Compound: 5'-d(*ap*ap*gp*gp*ap*ap*ap*gp*tp*cp*cp*c)-3'

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1le9A (A:)
mayveiieqpkqrgmrfrykcegrsagsipgerstdttkthptikingytgpgtvrislv
tkdpphrphphelvgkdcrdgyyeadlcpdrsihsfqnlgiqcvkkrdleqaisqriqtn
nnpfhvpieeqrgdydlnavrlcfqvtvrdpagrpllltpvlshpifdnrapntaelkic
rvnrnsgsclggdeifllcdkvqkedievyftgpgweargsfsqadvhrqvaivfrtppy
adpslqapvrvsmqlrrpsdrelsepmefqylpd

    Sequence, based on observed residues (ATOM records): (download) 
    >1le9A (A:)
ayveiieqpkqrgmrfrykcegrsagsipgerstdttkthptikingytgpgtvrislvt
kdpphrphphelvgkdcrdgyyeadlcpdrsihsfqnlgiqcvkkrdleqaisqriqtnn
npfhvpieeqrgdydlnavrlcfqvtvrdpagrpllltpvlshpifdnrapntaelkicr
vnrnsgsclggdeifllcdkvqkedievyftgpgweargsfsqadvhrqvaivfrtppya
dpslqapvrvsmqlrrpsdrelsepmefqylpd

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1le9B (B:)
mgpylqileqpkqrgfrfryvcegpshgglpgasseknkksypqvkicnyvgpakvivql
vtngknihlhahslvgkhcedgvctvtagpkdmvvgfanlgilhvtkkkvfetlearmte
acirgynpgllvhsdlaylqaegggdrqltdrekeiirqaavqqtkemdlsvvrlmftaf
lpdstgsftrrlepvvsdaiydskapnasnlkivrmdrtagcvtggeeiyllcdkvqkdd
iqirfyeeeenggvwegfgdfsptdvhrqfaivfktpkykdvnitkpasvfvqlrrksdl
etsepkpflyype

    Sequence, based on observed residues (ATOM records): (download) 
    >1le9B (B:)
gpylqileqpkqrgfrfryvcegpshgglpgasseknkksypqvkicnyvgpakvivqlv
tngknihlhahslvgkhcedgvctvtagpkdmvvgfanlgilhvtkkkvfetlearmtea
cirgynpgllvhsdlaylqaegggdrqltdrekeiirqaavqqtkemdlsvvrlmftafl
pdstgsftrrlepvvsdaiydskapnasnlkivrmdrtagcvtggeeiyllcdkvqkddi
qirfyeeeenggvwegfgdfsptdvhrqfaivfktpkykdvnitkpasvfvqlrrksdle
tsepkpflyype

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >1le9E (E:)
mayveiieqpkqrgmrfrykcegrsagsipgerstdttkthptikingytgpgtvrislv
tkdpphrphphelvgkdcrdgyyeadlcpdrsihsfqnlgiqcvkkrdleqaisqriqtn
nnpfhvpieeqrgdydlnavrlcfqvtvrdpagrpllltpvlshpifdnrapntaelkic
rvnrnsgsclggdeifllcdkvqkedievyftgpgweargsfsqadvhrqvaivfrtppy
adpslqapvrvsmqlrrpsdrelsepmefqylpd

    Sequence, based on observed residues (ATOM records): (download) 
    >1le9E (E:)
ayveiieqpkqrgmrfrykcegrsagsipgerstdttkthptikingytgpgtvrislvt
kdpphrphphelvgkdcrdgyyeadlcpdrsihsfqnlgiqcvkkrdleqaisqriqtnn
npfhvpieeqrgdydlnavrlcfqvtvrdpagrpllltpvlshpifdnrapntaelkicr
vnrnsgsclggdeifllcdkvqkedievyftgpgweargsfsqadvhrqvaivfrtppya
dpslqapvrvsmqlrrpsdrelsepmefqylpd

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >1le9F (F:)
mgpylqileqpkqrgfrfryvcegpshgglpgasseknkksypqvkicnyvgpakvivql
vtngknihlhahslvgkhcedgvctvtagpkdmvvgfanlgilhvtkkkvfetlearmte
acirgynpgllvhsdlaylqaegggdrqltdrekeiirqaavqqtkemdlsvvrlmftaf
lpdstgsftrrlepvvsdaiydskapnasnlkivrmdrtagcvtggeeiyllcdkvqkdd
iqirfyeeeenggvwegfgdfsptdvhrqfaivfktpkykdvnitkpasvfvqlrrksdl
etsepkpflyype

    Sequence, based on observed residues (ATOM records): (download) 
    >1le9F (F:)
gpylqileqpkqrgfrfryvcegpshgglpgasseknkksypqvkicnyvgpakvivqlv
tngknihlhahslvgkhcedgvctvtagpkdmvvgfanlgilhvtkkkvfetlearmtea
cirgynpgllvhsdlaylqaegggdrqltdrekeiirqaavqqtkemdlsvvrlmftafl
pdstgsftrrlepvvsdaiydskapnasnlkivrmdrtagcvtggeeiyllcdkvqkddi
qirfyeeeenggvwegfgdfsptdvhrqfaivfktpkykdvnitkpasvfvqlrrksdle
tsepkpflyype

  • Chain 'G':
    No sequence available.

  • Chain 'H':
    No sequence available.