Lineage for Protein: Ribonucleotide reductase R2

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 1988413Fold a.25: Ferritin-like [47239] (6 superfamilies)
    core: 4 helices; bundle, closed, left-handed twist; 1 crossover connection
  4. 1988414Superfamily a.25.1: Ferritin-like [47240] (10 families) (S)
    contains bimetal-ion centre in the middle of the bundle
  5. 1990025Family a.25.1.2: Ribonucleotide reductase-like [47253] (9 protein domains)
  6. 1990178Protein Ribonucleotide reductase R2 [47257] (10 species)

Species:

  1. 1990179Baker's yeast (Saccharomyces cerevisiae), Y2 [TaxId:4932] [88795] (2 PDB entries)
    Uniprot P09938
    1. Domain for 1jk0:
    2. Domains for 1smq:
      1. 1990181Domain d1smqa_: 1smq A: [105766]
      2. 1990182Domain d1smqb_: 1smq B: [105767]
      3. 1990183Domain d1smqc_: 1smq C: [105768]
      4. 1990184Domain d1smqd_: 1smq D: [105769]
  2. 1990185Baker's yeast (Saccharomyces cerevisiae), Y4 [TaxId:4932] [88796] (2 PDB entries)
    Uniprot P49723
    1. Domain for 1jk0:
    2. Domains for 1sms:
      1. 1990187Domain d1smsa_: 1sms A: [105770]
        complexed with hg
      2. 1990188Domain d1smsb_: 1sms B: [105771]
        complexed with hg
  3. 1990189Chlamydia trachomatis [TaxId:813] [109786] (1 PDB entry)
    Uniprot O84835
  4. 1990191Corynebacterium ammoniagenes [TaxId:1697] [69006] (6 PDB entries)
    1. Domains for 1kgn:
      1. 1990196Domain d1kgna_: 1kgn A: [68584]
        complexed with fe
      2. 1990197Domain d1kgnb_: 1kgn B: [68585]
        complexed with fe
      3. 1990198Domain d1kgnc_: 1kgn C: [68586]
        complexed with fe
      4. 1990199Domain d1kgnd_: 1kgn D: [68587]
        complexed with fe
    2. Domains for 1kgo:
      1. 1990208Domain d1kgoa_: 1kgo A: [68588]
        complexed with fe2
      2. 1990209Domain d1kgob_: 1kgo B: [68589]
        complexed with fe2
      3. 1990210Domain d1kgoc_: 1kgo C: [68590]
        complexed with fe2
      4. 1990211Domain d1kgod_: 1kgo D: [68591]
        complexed with fe2
    3. Domains for 1kgp:
      1. 1990200Domain d1kgpa_: 1kgp A: [68592]
        complexed with mn
      2. 1990201Domain d1kgpb_: 1kgp B: [68593]
        complexed with mn
      3. 1990202Domain d1kgpc_: 1kgp C: [68594]
        complexed with mn
      4. 1990203Domain d1kgpd_: 1kgp D: [68595]
        complexed with mn
    4. Domains for 1oqu:
      1. 1990204Domain d1oqua_: 1oqu A: [93435]
        complexed with act, fe, oxy
      2. 1990205Domain d1oqub_: 1oqu B: [93436]
        complexed with act, fe, oxy
      3. 1990206Domain d1oquc_: 1oqu C: [93437]
        complexed with act, fe, oxy
      4. 1990207Domain d1oqud_: 1oqu D: [93438]
        complexed with act, fe, oxy
    5. Domains for 3dhz:
      1. 1990194Domain d3dhza_: 3dhz A: [157741]
        automated match to d1oquc_
        complexed with fe2
      2. 1990195Domain d3dhzb_: 3dhz B: [157742]
        automated match to d1oquc_
        complexed with fe2
    6. Domains for 3mjo:
      1. 1990192Domain d3mjoa_: 3mjo A: [181304]
        automated match to d1kgna_
        complexed with mn3
      2. 1990193Domain d3mjob_: 3mjo B: [181305]
        automated match to d1kgna_
        complexed with mn3
  5. 1990212Escherichia coli [TaxId:562] [47258] (24 PDB entries)
    1. Domains for 1av8:
      1. 1990255Domain d1av8a_: 1av8 A: [16796]
        complexed with feo
      2. 1990256Domain d1av8b_: 1av8 B: [16797]
        complexed with feo
    2. Domains for 1biq:
      1. 1990239Domain d1biqa_: 1biq A: [16786]
        complexed with fe, fe2, hg, oh; mutant
      2. 1990240Domain d1biqb_: 1biq B: [16787]
        complexed with fe, fe2, hg, oh; mutant
    3. Domains for 1jpr:
      1. 1990219Domain d1jpra_: 1jpr A: [63224]
        complexed with hg, mn
      2. 1990220Domain d1jprb_: 1jpr B: [63225]
        complexed with hg, mn
    4. Domains for 1jqc:
      1. 1990215Domain d1jqca_: 1jqc A: [63229]
        complexed with hg, mn
      2. 1990216Domain d1jqcb_: 1jqc B: [63230]
        complexed with hg, mn
    5. Domains for 1mrr:
      1. 1990257Domain d1mrra_: 1mrr A: [16794]
        complexed with hg, mn
      2. 1990258Domain d1mrrb_: 1mrr B: [16795]
        complexed with hg, mn
    6. Domains for 1mxr:
      1. 1990213Domain d1mxra_: 1mxr A: [85197]
        complexed with fe, gol, hg
      2. 1990214Domain d1mxrb_: 1mxr B: [85198]
        complexed with fe, gol, hg
    7. Domains for 1pfr:
      1. 1990245Domain d1pfra_: 1pfr A: [16790]
        complexed with fe, hg
      2. 1990246Domain d1pfrb_: 1pfr B: [16791]
        complexed with fe, hg
    8. Domains for 1pim:
      1. 1990237Domain d1pima_: 1pim A: [88117]
        complexed with fe, hg; mutant
      2. 1990238Domain d1pimb_: 1pim B: [88118]
        complexed with fe, hg; mutant
    9. Domains for 1piu:
      1. 1990241Domain d1piua_: 1piu A: [88119]
        complexed with fe, hg, o; mutant
      2. 1990242Domain d1piub_: 1piu B: [88120]
        complexed with fe, hg, o; mutant
    10. Domains for 1piy:
      1. 1990217Domain d1piya_: 1piy A: [94710]
        complexed with fe, hg
      2. 1990218Domain d1piyb_: 1piy B: [94711]
        complexed with fe, hg
    11. Domains for 1piz:
      1. 1990227Domain d1piza_: 1piz A: [94712]
        complexed with fe, hg; mutant
      2. 1990228Domain d1pizb_: 1piz B: [94713]
        complexed with fe, hg; mutant
    12. Domains for 1pj0:
      1. 1990231Domain d1pj0a_: 1pj0 A: [94714]
        complexed with fe, hg; mutant
      2. 1990232Domain d1pj0b_: 1pj0 B: [94715]
        complexed with fe, hg; mutant
    13. Domains for 1pj1:
      1. 1990229Domain d1pj1a_: 1pj1 A: [94716]
        complexed with fe, hg
      2. 1990230Domain d1pj1b_: 1pj1 B: [94717]
        complexed with fe, hg
    14. Domains for 1pm2:
      1. 1990221Domain d1pm2a_: 1pm2 A: [94887]
        complexed with hg, mn; mutant
      2. 1990222Domain d1pm2b_: 1pm2 B: [94888]
        complexed with hg, mn; mutant
    15. Domains for 1r65:
      1. 1990233Domain d1r65a_: 1r65 A: [97144]
        complexed with fe2, hg
      2. 1990234Domain d1r65b_: 1r65 B: [97145]
        complexed with fe2, hg
    16. Domains for 1rib:
      1. 1990243Domain d1riba_: 1rib A: [16788]
        complexed with feo
      2. 1990244Domain d1ribb_: 1rib B: [16789]
        complexed with feo
    17. Domains for 1rnr:
      1. 1990253Domain d1rnra_: 1rnr A: [16798]
        complexed with fe, hg
      2. 1990254Domain d1rnrb_: 1rnr B: [16799]
        complexed with fe, hg
    18. Domains for 1rsr:
      1. 1990235Domain d1rsra_: 1rsr A: [97815]
        complexed with azi, fe2, hg; mutant
      2. 1990236Domain d1rsrb_: 1rsr B: [97816]
        complexed with azi, fe2, hg; mutant
    19. Domains for 1rsv:
      1. 1990249Domain d1rsva_: 1rsv A: [97817]
        complexed with azi, fe, hg; mutant
      2. 1990250Domain d1rsvb_: 1rsv B: [97818]
        complexed with azi, fe, hg; mutant
    20. Domains for 1xik:
      1. 1990225Domain d1xika_: 1xik A: [16784]
        complexed with fe2, hg
      2. 1990226Domain d1xikb_: 1xik B: [16785]
        complexed with fe2, hg
    21. Domains for 1yfd:
      1. 1990223Domain d1yfda1: 1yfd A:1-340 [123059]
        complexed with feo, hg; mutant
      2. 1990224Domain d1yfdb_: 1yfd B: [123060]
        automated match to d1yfda1
        complexed with feo, hg; mutant
    22. Domain for 2alx:
    23. Domains for 2av8:
      1. 1990251Domain d2av8a_: 2av8 A: [16792]
        complexed with fe2, feo; mutant
      2. 1990252Domain d2av8b_: 2av8 B: [16793]
        complexed with fe2, feo; mutant
    24. Domains for 2xof:
      1. 1990247Domain d2xofa_: 2xof A: [207288]
        automated match to d1jqcb_
        complexed with feo
      2. 1990248Domain d2xofb_: 2xof B: [207289]
        automated match to d1jqcb_
        complexed with feo
  6. 1990260Human (Homo sapiens), RRM2 [TaxId:9606] [158401] (1 PDB entry)
    Uniprot P31350 66-350
  7. 1990262Mouse (Mus musculus) [TaxId:10090] [47260] (5 PDB entries)
    Uniprot P11157
    1. Domain for 1h0n:
    2. Domain for 1h0o:
    3. Domain for 1w68:
    4. Domain for 1w69:
    5. Domain for 1xsm:
  8. 1990268Mycobacterium tuberculosis [TaxId:1773] [109787] (1 PDB entry)
    Uniprot Q50549 10-291
  9. 1990272Salmonella typhimurium [TaxId:90371] [47259] (3 PDB entries)
    1. Domains for 1r2f:
      1. 1990273Domain d1r2fa_: 1r2f A: [16800]
        complexed with fe
      2. 1990274Domain d1r2fb_: 1r2f B: [16801]
        complexed with fe
    2. Domains for 2bq1:
      1. 1990277Domain d2bq1i1: 2bq1 I:6-288 [128957]
        Other proteins in same PDB: d2bq1e1, d2bq1e2, d2bq1f1, d2bq1f2
        automatically matched to d2r2fa_
        protein/DNA complex; complexed with dgt, fe, mg
      2. 1990278Domain d2bq1j1: 2bq1 J:6-286 [128958]
        Other proteins in same PDB: d2bq1e1, d2bq1e2, d2bq1f1, d2bq1f2
        automatically matched to d2r2fa_
        protein/DNA complex; complexed with dgt, fe, mg
    3. Domains for 2r2f:
      1. 1990275Domain d2r2fa_: 2r2f A: [16802]
        complexed with feo
      2. 1990276Domain d2r2fb_: 2r2f B: [16803]
        complexed with feo
  10. 2275506Escherichia coli [TaxId:745156] [318807] (1 PDB entry)

More info for Protein Ribonucleotide reductase R2 from a.25.1.2: Ribonucleotide reductase-like

Timeline for Protein Ribonucleotide reductase R2 from a.25.1.2: Ribonucleotide reductase-like: