SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for Family a.25.1.2: Ribonucleotide reductase-like

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 1988413Fold a.25: Ferritin-like [47239] (6 superfamilies)
    core: 4 helices; bundle, closed, left-handed twist; 1 crossover connection
  4. 1988414Superfamily a.25.1: Ferritin-like [47240] (10 families) (S)
    contains bimetal-ion centre in the middle of the bundle
  5. 1990025Family a.25.1.2: Ribonucleotide reductase-like [47253] (9 protein domains)

Protein Domains:

  1. 1990026delta 9-stearoyl-acyl carrier protein desaturase [47261] (1 species)
  2. 1990053Methane monooxygenase hydrolase alpha subunit [88789] (2 species)
    1. 1990054Species Methylococcus capsulatus [TaxId:414] [88790] (26 PDB entries)
    2. 1990107Species Methylosinus trichosporium [TaxId:426] [88791] (2 PDB entries)
  3. 1990110Methane monooxygenase hydrolase beta subunit [88792] (2 species)
    1. 1990111Species Methylococcus capsulatus [TaxId:414] [88793] (27 PDB entries)
    2. 1990168Species Methylosinus trichosporium [TaxId:426] [88794] (2 PDB entries)
  4. 1990171Phenylacetic acid degradation protein PaaC [101136] (1 species)
  5. 1990175Possible acyl-[acyl-carrier protein] desaturase [140442] (1 species)
  6. 1990178Ribonucleotide reductase R2 [47257] (10 species)
    1. 1990179Species Baker's yeast (Saccharomyces cerevisiae), Y2 [TaxId:4932] [88795] (2 PDB entries)
      Uniprot P09938
    2. 1990185Species Baker's yeast (Saccharomyces cerevisiae), Y4 [TaxId:4932] [88796] (2 PDB entries)
      Uniprot P49723
    3. 1990189Species Chlamydia trachomatis [TaxId:813] [109786] (1 PDB entry)
      Uniprot O84835
    4. 1990191Species Corynebacterium ammoniagenes [TaxId:1697] [69006] (6 PDB entries)
    5. 1990212Species Escherichia coli [TaxId:562] [47258] (24 PDB entries)
    6. 1990260Species Human (Homo sapiens), RRM2 [TaxId:9606] [158401] (1 PDB entry)
      Uniprot P31350 66-350
    7. 1990262Species Mouse (Mus musculus) [TaxId:10090] [47260] (5 PDB entries)
      Uniprot P11157
    8. 1990268Species Mycobacterium tuberculosis [TaxId:1773] [109787] (1 PDB entry)
      Uniprot Q50549 10-291
    9. 1990272Species Salmonella typhimurium [TaxId:90371] [47259] (3 PDB entries)
    10. 2275506Species Escherichia coli [TaxId:745156] [318807] (1 PDB entry)
  7. 1990279Toluene, o-xylene monooxygenase oxygenase subunit TouA [109788] (2 species)
    contains the TouB(TmoB)-binding YHS (sub)domain (Pfam PF04945) in the C-terminal part (401-450)
    1. 1990280Species Pseudomonas sp. [TaxId:320855] [189497] (11 PDB entries)
    2. 1990292Species Pseudomonas stutzeri [TaxId:316] [109789] (6 PDB entries)
      Uniprot O87798
  8. 1990299Toluene, o-xylene monooxygenase oxygenase subunit TouE [109790] (2 species)
    1. 1990300Species Pseudomonas sp. [TaxId:320855] [189498] (11 PDB entries)
    2. 1990312Species Pseudomonas stutzeri [TaxId:316] [109791] (6 PDB entries)
      Uniprot O87802
  9. 1990319automated matches [190435] (11 species)
    not a true protein
    1. 1990320Species Castor bean (Ricinus communis) [TaxId:3988] [187330] (3 PDB entries)
    2. 1990336Species Chlamydia trachomatis [TaxId:813] [225098] (5 PDB entries)
    3. 1990354Species Escherichia coli K-12 [TaxId:83333] [255975] (6 PDB entries)
    4. 1990364Species Escherichia coli [TaxId:511145] [189613] (7 PDB entries)
    5. 1990385Species Hedera helix [TaxId:4052] [187347] (1 PDB entry)
    6. 1990388Species Human (Homo sapiens) [TaxId:9606] [193902] (7 PDB entries)
    7. 1990403Species Methylococcus capsulatus [TaxId:243233] [226584] (1 PDB entry)
    8. 1990408Species Plasmodium vivax [TaxId:5855] [226817] (1 PDB entry)
    9. 1990411Species Pseudomonas mendocina [TaxId:300] [188695] (16 PDB entries)
    10. 2275396Species Escherichia coli [TaxId:745156] [318697] (2 PDB entries)
    11. 2275443Species Escherichia coli [TaxId:83334] [318744] (2 PDB entries)

More info for Family a.25.1.2: Ribonucleotide reductase-like

Timeline for Family a.25.1.2: Ribonucleotide reductase-like: