Lineage for Protein: 3-hydroxy-3-methylglutaryl CoA synthase MvaS, C-terminal domain

  1. Root: SCOPe 2.08
  2. 2826024Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2916469Fold c.95: Thiolase-like [53900] (1 superfamily)
    consists of two similar domains related by pseudo dyad; duplication
    3 layers: a/b/a; mixed beta-sheet of 5 strands, order 32451; strand 5 is antiparallel to the rest
  4. 2916470Superfamily c.95.1: Thiolase-like [53901] (3 families) (S)
  5. 2916987Family c.95.1.2: Chalcone synthase-like [53914] (15 proteins)
  6. 2916988Protein 3-hydroxy-3-methylglutaryl CoA synthase MvaS, C-terminal domain [419029] (2 species)
    most similar to FabH

Species:

  1. 2916989Enterococcus faecalis [TaxId:1351] [419511] (4 PDB entries)
    1. Domains for 1x9e:
      1. 2916998Domain d1x9ea2: 1x9e A:168-383 [203078]
        Other proteins in same PDB: d1x9ea1, d1x9eb1
        automated match to d1xpma2
        complexed with so4
        has additional subdomain(s) that are not in the common domain
      2. 2916999Domain d1x9eb2: 1x9e B:168-383 [203080]
        Other proteins in same PDB: d1x9ea1, d1x9eb1
        automated match to d1xpma2
        complexed with so4
        has additional subdomain(s) that are not in the common domain
    2. Domains for 2hdb:
      1. 2917000Domain d2hdba2: 2hdb A:168-383 [204541]
        Other proteins in same PDB: d2hdba1, d2hdbb1
        automated match to d1xpma2
        complexed with mes, so4; mutant
        has additional subdomain(s) that are not in the common domain
      2. 2917001Domain d2hdbb2: 2hdb B:168-383 [204543]
        Other proteins in same PDB: d2hdba1, d2hdbb1
        automated match to d1xpma2
        complexed with mes, so4; mutant
        has additional subdomain(s) that are not in the common domain
    3. Domains for 3v4n:
      1. 2916990Domain d3v4na2: 3v4n A:168-383 [217640]
        Other proteins in same PDB: d3v4na1, d3v4na3, d3v4nb1, d3v4nb3, d3v4nc1, d3v4nd1
        automated match to d1xpma2
        complexed with btb
        has additional subdomain(s) that are not in the common domain
      2. 2916991Domain d3v4nb2: 3v4n B:168-383 [217642]
        Other proteins in same PDB: d3v4na1, d3v4na3, d3v4nb1, d3v4nb3, d3v4nc1, d3v4nd1
        automated match to d1xpma2
        complexed with btb
        has additional subdomain(s) that are not in the common domain
      3. 2916992Domain d3v4nc2: 3v4n C:168-383 [217644]
        Other proteins in same PDB: d3v4na1, d3v4na3, d3v4nb1, d3v4nb3, d3v4nc1, d3v4nd1
        automated match to d1xpma2
        complexed with btb
        has additional subdomain(s) that are not in the common domain
      4. 2916993Domain d3v4nd2: 3v4n D:168-383 [217646]
        Other proteins in same PDB: d3v4na1, d3v4na3, d3v4nb1, d3v4nb3, d3v4nc1, d3v4nd1
        automated match to d1xpma2
        complexed with btb
        has additional subdomain(s) that are not in the common domain
    4. Domains for 3v4x:
      1. 2916994Domain d3v4xa2: 3v4x A:168-383 [217656]
        Other proteins in same PDB: d3v4xa1, d3v4xa3, d3v4xb1, d3v4xb3, d3v4xc1, d3v4xc3, d3v4xd1, d3v4xd3
        automated match to d1xpma2
        complexed with f24
        has additional subdomain(s) that are not in the common domain
      2. 2916995Domain d3v4xb2: 3v4x B:168-383 [217658]
        Other proteins in same PDB: d3v4xa1, d3v4xa3, d3v4xb1, d3v4xb3, d3v4xc1, d3v4xc3, d3v4xd1, d3v4xd3
        automated match to d1xpma2
        complexed with f24
        has additional subdomain(s) that are not in the common domain
      3. 2916996Domain d3v4xc2: 3v4x C:168-383 [217660]
        Other proteins in same PDB: d3v4xa1, d3v4xa3, d3v4xb1, d3v4xb3, d3v4xc1, d3v4xc3, d3v4xd1, d3v4xd3
        automated match to d1xpma2
        complexed with f24
        has additional subdomain(s) that are not in the common domain
      4. 2916997Domain d3v4xd2: 3v4x D:168-383 [217662]
        Other proteins in same PDB: d3v4xa1, d3v4xa3, d3v4xb1, d3v4xb3, d3v4xc1, d3v4xc3, d3v4xd1, d3v4xd3
        automated match to d1xpma2
        complexed with f24
        has additional subdomain(s) that are not in the common domain
  2. Staphylococcus aureus [TaxId:1280] [419513] (5 PDB entries)
    Uniprot Q7A3F6
    1. Domain for 1tvz:
      • 2917003Domain d1tvza2: 1tvz A:168-388 [107368]
        Other proteins in same PDB: d1tvza1
        complexed with so4
        has additional subdomain(s) that are not in the common domain
    2. Domains for 1txt:
      1. 2917008Domain d1txta2: 1txt A:168-388 [107432]
        Other proteins in same PDB: d1txta1, d1txtb1, d1txtc1, d1txtd1
        complexed with caa
        has additional subdomain(s) that are not in the common domain
      2. 2917009Domain d1txtb2: 1txt B:168-388 [107434]
        Other proteins in same PDB: d1txta1, d1txtb1, d1txtc1, d1txtd1
        complexed with caa
        has additional subdomain(s) that are not in the common domain
      3. 2917010Domain d1txtc2: 1txt C:168-388 [107436]
        Other proteins in same PDB: d1txta1, d1txtb1, d1txtc1, d1txtd1
        complexed with caa
        has additional subdomain(s) that are not in the common domain
      4. 2917011Domain d1txtd2: 1txt D:168-388 [107438]
        Other proteins in same PDB: d1txta1, d1txtb1, d1txtc1, d1txtd1
        complexed with caa
        has additional subdomain(s) that are not in the common domain
    3. Domains for 1xpk:
      1. 2917016Domain d1xpka2: 1xpk A:168-388 [115744]
        Other proteins in same PDB: d1xpka1, d1xpkb1, d1xpkc1, d1xpkd1
        complexed with caa, hmg, so4
        has additional subdomain(s) that are not in the common domain
      2. 2917017Domain d1xpkb2: 1xpk B:168-388 [115746]
        Other proteins in same PDB: d1xpka1, d1xpkb1, d1xpkc1, d1xpkd1
        complexed with caa, hmg, so4
        has additional subdomain(s) that are not in the common domain
      3. 2917018Domain d1xpkc2: 1xpk C:168-388 [115748]
        Other proteins in same PDB: d1xpka1, d1xpkb1, d1xpkc1, d1xpkd1
        complexed with caa, hmg, so4
        has additional subdomain(s) that are not in the common domain
      4. 2917019Domain d1xpkd2: 1xpk D:168-388 [115750]
        Other proteins in same PDB: d1xpka1, d1xpkb1, d1xpkc1, d1xpkd1
        complexed with caa, hmg, so4
        has additional subdomain(s) that are not in the common domain
    4. Domains for 1xpl:
      1. 2917012Domain d1xpla2: 1xpl A:168-388 [115752]
        Other proteins in same PDB: d1xpla1, d1xpla3, d1xpla4, d1xplb1, d1xplb3, d1xplb4, d1xplc1, d1xplc3, d1xplc4, d1xpld1, d1xpld3, d1xpld4
        complexed with caa, so4
        has additional subdomain(s) that are not in the common domain
      2. 2917013Domain d1xplb2: 1xpl B:168-388 [115754]
        Other proteins in same PDB: d1xpla1, d1xpla3, d1xpla4, d1xplb1, d1xplb3, d1xplb4, d1xplc1, d1xplc3, d1xplc4, d1xpld1, d1xpld3, d1xpld4
        complexed with caa, so4
        has additional subdomain(s) that are not in the common domain
      3. 2917014Domain d1xplc2: 1xpl C:168-388 [115756]
        Other proteins in same PDB: d1xpla1, d1xpla3, d1xpla4, d1xplb1, d1xplb3, d1xplb4, d1xplc1, d1xplc3, d1xplc4, d1xpld1, d1xpld3, d1xpld4
        complexed with caa, so4
        has additional subdomain(s) that are not in the common domain
      4. 2917015Domain d1xpld2: 1xpl D:168-388 [115758]
        Other proteins in same PDB: d1xpla1, d1xpla3, d1xpla4, d1xplb1, d1xplb3, d1xplb4, d1xplc1, d1xplc3, d1xplc4, d1xpld1, d1xpld3, d1xpld4
        complexed with caa, so4
        has additional subdomain(s) that are not in the common domain
    5. Domains for 1xpm:
      1. 2917004Domain d1xpma2: 1xpm A:168-388 [115760]
        Other proteins in same PDB: d1xpma1, d1xpma3, d1xpma4, d1xpmb1, d1xpmb3, d1xpmb4, d1xpmc1, d1xpmc3, d1xpmc4, d1xpmd1, d1xpmd3, d1xpmd4
        complexed with caa, hmg, so4
        has additional subdomain(s) that are not in the common domain
      2. 2917005Domain d1xpmb2: 1xpm B:168-388 [115762]
        Other proteins in same PDB: d1xpma1, d1xpma3, d1xpma4, d1xpmb1, d1xpmb3, d1xpmb4, d1xpmc1, d1xpmc3, d1xpmc4, d1xpmd1, d1xpmd3, d1xpmd4
        complexed with caa, hmg, so4
        has additional subdomain(s) that are not in the common domain
      3. 2917006Domain d1xpmc2: 1xpm C:168-388 [115764]
        Other proteins in same PDB: d1xpma1, d1xpma3, d1xpma4, d1xpmb1, d1xpmb3, d1xpmb4, d1xpmc1, d1xpmc3, d1xpmc4, d1xpmd1, d1xpmd3, d1xpmd4
        complexed with caa, hmg, so4
        has additional subdomain(s) that are not in the common domain
      4. 2917007Domain d1xpmd2: 1xpm D:168-388 [115766]
        Other proteins in same PDB: d1xpma1, d1xpma3, d1xpma4, d1xpmb1, d1xpmb3, d1xpmb4, d1xpmc1, d1xpmc3, d1xpmc4, d1xpmd1, d1xpmd3, d1xpmd4
        complexed with caa, hmg, so4
        has additional subdomain(s) that are not in the common domain

More info for Protein 3-hydroxy-3-methylglutaryl CoA synthase MvaS, C-terminal domain from c.95.1.2: Chalcone synthase-like

Timeline for Protein 3-hydroxy-3-methylglutaryl CoA synthase MvaS, C-terminal domain from c.95.1.2: Chalcone synthase-like:

  • Protein 3-hydroxy-3-methylglutaryl CoA synthase MvaS, C-terminal domain from c.95.1.2: Chalcone synthase-like is new in SCOPe 2.08-stable