Lineage for d3v4nc2 (3v4n C:168-383)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2146372Fold c.95: Thiolase-like [53900] (1 superfamily)
    consists of two similar domains related by pseudo dyad; duplication
    3 layers: a/b/a; mixed beta-sheet of 5 strands, order 32451; strand 5 is antiparallel to the rest
  4. 2146373Superfamily c.95.1: Thiolase-like [53901] (3 families) (S)
  5. 2146851Family c.95.1.2: Chalcone synthase-like [53914] (9 protein domains)
  6. 2146852Protein 3-hydroxy-3-methylglutaryl CoA synthase MvaS [110760] (2 species)
    most similar to FabH
  7. 2146853Species Enterococcus faecalis [TaxId:1351] [225034] (4 PDB entries)
  8. 2146859Domain d3v4nc2: 3v4n C:168-383 [217644]
    Other proteins in same PDB: d3v4na3, d3v4nb3
    automated match to d1xpma2
    complexed with btb

Details for d3v4nc2

PDB Entry: 3v4n (more details), 1.6 Å

PDB Description: The Biochemical and Structural Basis for Inhibition of Enterococcus faecalis HMG-CoA Synthatse, mvaS, by Hymeglusin
PDB Compounds: (C:) HMG-CoA synthase

SCOPe Domain Sequences for d3v4nc2:

Sequence; same for both SEQRES and ATOM records: (download)

>d3v4nc2 c.95.1.2 (C:168-383) 3-hydroxy-3-methylglutaryl CoA synthase MvaS {Enterococcus faecalis [TaxId: 1351]}

SCOPe Domain Coordinates for d3v4nc2:

Click to download the PDB-style file with coordinates for d3v4nc2.
(The format of our PDB-style files is described here.)

Timeline for d3v4nc2: