SCOPe 2.03: Protein: p53 tumor suppressor, DNA-binding domain

Lineage for Protein: p53 tumor suppressor, DNA-binding domain

Root: SCOPe 2.03
Class b: All beta proteins [48724] (174 folds)
Fold b.2: Common fold of diphtheria toxin/transcription factors/cytochrome f [49379] (10 superfamilies)
sandwich; 9 strands in 2 sheet; greek-key; subclass of immunoglobin-like fold
Superfamily b.2.5: p53-like transcription factors [49417] (7 families)
Family b.2.5.2: p53 DNA-binding domain-like [81314] (3 proteins)
Protein p53 tumor suppressor, DNA-binding domain [49419] (2 species)

Species:

Human (Homo sapiens) [TaxId:9606] [49420] (32 PDB entries)

Domains for 1gzh:
1. Domain d1gzha_: 1gzh A: [70807]
  Other proteins in same PDB: d1gzhb1, d1gzhb2, d1gzhd1, d1gzhd2
  complexed with so4, zn
2. Domain d1gzhc_: 1gzh C: [70810]
  Other proteins in same PDB: d1gzhb1, d1gzhb2, d1gzhd1, d1gzhd2
  complexed with so4, zn
Domains for 1kzy:
1. Domain d1kzya_: 1kzy A: [73381]
  Other proteins in same PDB: d1kzyc1, d1kzyc2, d1kzyd1, d1kzyd2
  protein/DNA complex; complexed with zn
2. Domain d1kzyb_: 1kzy B: [73382]
  Other proteins in same PDB: d1kzyc1, d1kzyc2, d1kzyd1, d1kzyd2
  protein/DNA complex; complexed with zn
Domains for 1tsr:
1. Domain d1tsra_: 1tsr A: [22437]
  protein/DNA complex; complexed with zn
2. Domain d1tsrb_: 1tsr B: [22438]
  protein/DNA complex; complexed with zn
3. Domain d1tsrc_: 1tsr C: [22439]
  protein/DNA complex; complexed with zn
Domains for 1tup:
1. Domain d1tupa_: 1tup A: [22434]
  protein/DNA complex; complexed with zn
2. Domain d1tupb_: 1tup B: [22435]
  protein/DNA complex; complexed with zn
3. Domain d1tupc_: 1tup C: [22436]
  protein/DNA complex; complexed with zn
Domains for 1uol:
1. Domain d1uola_: 1uol A: [99695]
  complexed with zn; mutant
2. Domain d1uolb_: 1uol B: [99696]
  complexed with zn; mutant
Domain for 1ycs:
- Domain d1ycsa_: 1ycs A: [22433]
  Other proteins in same PDB: d1ycsb1, d1ycsb2
  complexed with zn
Domain for 2fej:
- Domain d2feja1: 2fej A:96-290 [133349]
  automatically matched to d1uola_
  complexed with zn

Domains for 2h1l:

Domain d2h1lm1: 2h1l M:96-289 [135959]
Other proteins in same PDB: d2h1la1, d2h1lb1, d2h1lc1, d2h1ld1, d2h1le1, d2h1lf1, d2h1lg1, d2h1lh1, d2h1li1, d2h1lj1, d2h1lk1, d2h1ll1
automatically matched to d1uola_
complexed with zn

Domain d2h1ln1: 2h1l N:96-289 [135960]
Other proteins in same PDB: d2h1la1, d2h1lb1, d2h1lc1, d2h1ld1, d2h1le1, d2h1lf1, d2h1lg1, d2h1lh1, d2h1li1, d2h1lj1, d2h1lk1, d2h1ll1
automatically matched to d1uola_
complexed with zn

Domain d2h1lo1: 2h1l O:96-289 [135961]
Other proteins in same PDB: d2h1la1, d2h1lb1, d2h1lc1, d2h1ld1, d2h1le1, d2h1lf1, d2h1lg1, d2h1lh1, d2h1li1, d2h1lj1, d2h1lk1, d2h1ll1
automatically matched to d1uola_
complexed with zn

Domain d2h1lp1: 2h1l P:96-289 [135962]
Other proteins in same PDB: d2h1la1, d2h1lb1, d2h1lc1, d2h1ld1, d2h1le1, d2h1lf1, d2h1lg1, d2h1lh1, d2h1li1, d2h1lj1, d2h1lk1, d2h1ll1
automatically matched to d1uola_
complexed with zn

Domain d2h1lq1: 2h1l Q:96-289 [135963]
Other proteins in same PDB: d2h1la1, d2h1lb1, d2h1lc1, d2h1ld1, d2h1le1, d2h1lf1, d2h1lg1, d2h1lh1, d2h1li1, d2h1lj1, d2h1lk1, d2h1ll1
automatically matched to d1uola_
complexed with zn

Domain d2h1lr1: 2h1l R:96-289 [135964]
Other proteins in same PDB: d2h1la1, d2h1lb1, d2h1lc1, d2h1ld1, d2h1le1, d2h1lf1, d2h1lg1, d2h1lh1, d2h1li1, d2h1lj1, d2h1lk1, d2h1ll1
automatically matched to d1uola_
complexed with zn

Domain d2h1ls1: 2h1l S:96-289 [135965]
Other proteins in same PDB: d2h1la1, d2h1lb1, d2h1lc1, d2h1ld1, d2h1le1, d2h1lf1, d2h1lg1, d2h1lh1, d2h1li1, d2h1lj1, d2h1lk1, d2h1ll1
automatically matched to d1uola_
complexed with zn

Domain d2h1lt1: 2h1l T:96-289 [135966]
Other proteins in same PDB: d2h1la1, d2h1lb1, d2h1lc1, d2h1ld1, d2h1le1, d2h1lf1, d2h1lg1, d2h1lh1, d2h1li1, d2h1lj1, d2h1lk1, d2h1ll1
automatically matched to d1uola_
complexed with zn

Domain d2h1lu1: 2h1l U:96-289 [135967]
Other proteins in same PDB: d2h1la1, d2h1lb1, d2h1lc1, d2h1ld1, d2h1le1, d2h1lf1, d2h1lg1, d2h1lh1, d2h1li1, d2h1lj1, d2h1lk1, d2h1ll1
automatically matched to d1uola_
complexed with zn

Domain d2h1lv1: 2h1l V:96-289 [135968]
Other proteins in same PDB: d2h1la1, d2h1lb1, d2h1lc1, d2h1ld1, d2h1le1, d2h1lf1, d2h1lg1, d2h1lh1, d2h1li1, d2h1lj1, d2h1lk1, d2h1ll1
automatically matched to d1uola_
complexed with zn

Domain d2h1lw1: 2h1l W:96-289 [135969]
Other proteins in same PDB: d2h1la1, d2h1lb1, d2h1lc1, d2h1ld1, d2h1le1, d2h1lf1, d2h1lg1, d2h1lh1, d2h1li1, d2h1lj1, d2h1lk1, d2h1ll1
automatically matched to d1uola_
complexed with zn

Domain d2h1lx1: 2h1l X:96-289 [135970]
Other proteins in same PDB: d2h1la1, d2h1lb1, d2h1lc1, d2h1ld1, d2h1le1, d2h1lf1, d2h1lg1, d2h1lh1, d2h1li1, d2h1lj1, d2h1lk1, d2h1ll1
automatically matched to d1uola_
complexed with zn

Domain for 2pcx:
- Domain d2pcxa_: 2pcx A: [167134]
  automated match to d1gzha_
  complexed with zn
Domain for 3d05:
- Domain d3d05a_: 3d05 A: [173588]
  automated match to d1gzha_
  complexed with zn; mutant
Domain for 3d06:
- Domain d3d06a_: 3d06 A: [173589]
  automated match to d1gzha_
  complexed with zn; mutant
Domains for 3d07:
1. Domain d3d07a_: 3d07 A: [173590]
  automated match to d1gzha_
  complexed with zn; mutant
2. Domain d3d07b_: 3d07 B: [173591]
  automated match to d1gzha_
  complexed with zn; mutant
Domain for 3d08:
- Domain d3d08a_: 3d08 A: [173592]
  automated match to d1gzha_
  complexed with zn; mutant
Domain for 3d09:
- Domain d3d09a_: 3d09 A: [173593]
  automated match to d1gzha_
  complexed with zn; mutant
Domains for 3d0a:
1. Domain d3d0aa_: 3d0a A: [173594]
  automated match to d1gzha_
  protein/DNA complex; protein/RNA complex; complexed with zn; mutant
2. Domain d3d0ab_: 3d0a B: [173595]
  automated match to d1gzha_
  protein/DNA complex; protein/RNA complex; complexed with zn; mutant
3. Domain d3d0ac_: 3d0a C: [173596]
  automated match to d1gzha_
  protein/DNA complex; protein/RNA complex; complexed with zn; mutant
4. Domain d3d0ad_: 3d0a D: [173597]
  automated match to d1gzha_
  protein/DNA complex; protein/RNA complex; complexed with zn; mutant
Domain for 3igk:
- Domain d3igka_: 3igk A: [178310]
  automated match to d1gzha_
  protein/DNA complex; protein/RNA complex; complexed with zn
Domain for 3igl:
- Domain d3igla_: 3igl A: [178311]
  automated match to d1gzha_
  protein/DNA complex; protein/RNA complex; complexed with edo, zn
Domains for 3kz8:
1. Domain d3kz8a_: 3kz8 A: [179824]
  automated match to d1gzha_
  protein/DNA complex; complexed with iod, zn
2. Domain d3kz8b_: 3kz8 B: [179825]
  automated match to d1gzha_
  protein/DNA complex; complexed with iod, zn
Domains for 4ibq:
1. Domain d4ibqa_: 4ibq A: [223098]
  automated match to d2ahia_
  complexed with act, edo, zn; mutant
2. Domain d4ibqb_: 4ibq B: [223099]
  automated match to d2ahia_
  complexed with act, edo, zn; mutant
3. Domain d4ibqc_: 4ibq C: [223100]
  automated match to d2ahia_
  complexed with act, edo, zn; mutant
4. Domain d4ibqd_: 4ibq D: [223101]
  automated match to d2ahia_
  complexed with act, edo, zn; mutant
Domains for 4ibs:
1. Domain d4ibsa_: 4ibs A: [223102]
  automated match to d2ahia_
  complexed with edo, zn; mutant
2. Domain d4ibsb_: 4ibs B: [223103]
  automated match to d2ahia_
  complexed with edo, zn; mutant
3. Domain d4ibsc_: 4ibs C: [223104]
  automated match to d2ahia_
  complexed with edo, zn; mutant
4. Domain d4ibsd_: 4ibs D: [223105]
  automated match to d2ahia_
  complexed with edo, zn; mutant
Domains for 4ibt:
1. Domain d4ibta_: 4ibt A: [223106]
  automated match to d2ahia_
  complexed with zn; mutant
2. Domain d4ibtb_: 4ibt B: [223107]
  automated match to d2ahia_
  complexed with zn; mutant
3. Domain d4ibtc_: 4ibt C: [223108]
  automated match to d2ahia_
  complexed with zn; mutant
4. Domain d4ibtd_: 4ibt D: [223109]
  automated match to d2ahia_
  complexed with zn; mutant
Domains for 4ibu:
1. Domain d4ibua_: 4ibu A: [223110]
  automated match to d2ahia_
  protein/DNA complex; complexed with act, edo, zn; mutant
2. Domain d4ibub_: 4ibu B: [223111]
  automated match to d2ahia_
  protein/DNA complex; complexed with act, edo, zn; mutant
3. Domain d4ibuc_: 4ibu C: [223112]
  automated match to d2ahia_
  protein/DNA complex; complexed with act, edo, zn; mutant
4. Domain d4ibud_: 4ibu D: [223113]
  automated match to d2ahia_
  protein/DNA complex; complexed with act, edo, zn; mutant
Domain for 4ibv:
- Domain d4ibva_: 4ibv A: [223114]
  automated match to d2ahia_
  protein/DNA complex; complexed with edo, zn; mutant
Domain for 4ibw:
- Domain d4ibwa_: 4ibw A: [223115]
  automated match to d2ahia_
  protein/DNA complex; complexed with edo, zn; mutant
Domains for 4iby:
1. Domain d4ibya_: 4iby A: [223116]
  automated match to d2ahia_
  complexed with edo, zn; mutant
2. Domain d4ibyb_: 4iby B: [223117]
  automated match to d2ahia_
  complexed with edo, zn; mutant
Domains for 4ibz:
1. Domain d4ibza_: 4ibz A: [223118]
  automated match to d2ahia_
  complexed with act, edo, zn; mutant
2. Domain d4ibzb_: 4ibz B: [223119]
  automated match to d2ahia_
  complexed with act, edo, zn; mutant
3. Domain d4ibzc_: 4ibz C: [223120]
  automated match to d2ahia_
  complexed with act, edo, zn; mutant
4. Domain d4ibzd_: 4ibz D: [223121]
  automated match to d2ahia_
  complexed with act, edo, zn; mutant
Domain for 4ijt:
- Domain d4ijta_: 4ijt A: [223231]
  automated match to d2ahia_
  complexed with dtt, edo, zn; mutant
Domains for 4kvp:
1. Domain d4kvpa_: 4kvp A: [224494]
  complexed with zn; mutant
2. Domain d4kvpb_: 4kvp B: [224495]
  complexed with zn; mutant
3. Domain d4kvpc_: 4kvp C: [224496]
  complexed with zn; mutant
4. Domain d4kvpd_: 4kvp D: [224497]
  complexed with zn; mutant
Domains for 4lo9:
1. Domain d4lo9a_: 4lo9 A: [224722]
  complexed with zn; mutant
2. Domain d4lo9b_: 4lo9 B: [224723]
  complexed with zn; mutant
3. Domain d4lo9c_: 4lo9 C: [224724]
  complexed with zn; mutant
4. Domain d4lo9d_: 4lo9 D: [224725]
  complexed with zn; mutant
Domains for 4loe:
1. Domain d4loea_: 4loe A: [224726]
  complexed with zn; mutant
2. Domain d4loeb_: 4loe B: [224727]
  complexed with zn; mutant
3. Domain d4loec_: 4loe C: [224728]
  complexed with zn; mutant
4. Domain d4loed_: 4loe D: [224729]
  complexed with zn; mutant
Domain for 4lof:
- Domain d4lofa_: 4lof A: [224730]
  complexed with zn; mutant
Domain for 4mzi:
- Domain d4mzia_: 4mzi A: [236070]
  automated match to d3igla_
  complexed with zn; mutant

Mouse (Mus musculus) [TaxId:10090] [63683] (1 PDB entry)
- Domains for 1hu8:
  1. Domain d1hu8a_: 1hu8 A: [61269]
    complexed with zn
  2. Domain d1hu8b_: 1hu8 B: [61270]
    complexed with zn
  3. Domain d1hu8c_: 1hu8 C: [61271]
    complexed with zn

More info for Protein p53 tumor suppressor, DNA-binding domain from b.2.5.2: p53 DNA-binding domain-like

Timeline for Protein p53 tumor suppressor, DNA-binding domain from b.2.5.2: p53 DNA-binding domain-like:

Protein p53 tumor suppressor, DNA-binding domain from b.2.5.2: p53 DNA-binding domain-like first appeared (with stable ids) in SCOP 1.55, called Protein p53 tumor suppressor, DNA-binding domain from b.2.5.1: p53-like transcription factors
Protein p53 tumor suppressor, DNA-binding domain from b.2.5.2: p53 DNA-binding domain-like appears in SCOPe 2.02
Protein p53 tumor suppressor, DNA-binding domain from b.2.5.2: p53 DNA-binding domain-like appears in SCOPe 2.04
Protein p53 tumor suppressor, DNA-binding domain from b.2.5.2: p53 DNA-binding domain-like appears in the current release, SCOPe 2.08