SCOPe 2.02: Protein: p53 tumor suppressor, DNA-binding domain

Lineage for Protein: p53 tumor suppressor, DNA-binding domain

Root: SCOPe 2.02
Class b: All beta proteins [48724] (174 folds)
Fold b.2: Common fold of diphtheria toxin/transcription factors/cytochrome f [49379] (10 superfamilies)
sandwich; 9 strands in 2 sheet; greek-key; subclass of immunoglobin-like fold
Superfamily b.2.5: p53-like transcription factors [49417] (7 families)
Family b.2.5.2: p53 DNA-binding domain-like [81314] (3 proteins)
Protein p53 tumor suppressor, DNA-binding domain [49419] (2 species)

Species:

Human (Homo sapiens) [TaxId:9606] [49420] (22 PDB entries)

Domains for 1gzh:
1. Domain d1gzha_: 1gzh A: [70807]
  Other proteins in same PDB: d1gzhb1, d1gzhb2, d1gzhd1, d1gzhd2
  complexed with so4, zn
2. Domain d1gzhc_: 1gzh C: [70810]
  Other proteins in same PDB: d1gzhb1, d1gzhb2, d1gzhd1, d1gzhd2
  complexed with so4, zn
Domains for 1kzy:
1. Domain d1kzya_: 1kzy A: [73381]
  Other proteins in same PDB: d1kzyc1, d1kzyc2, d1kzyd1, d1kzyd2
  protein/DNA complex; complexed with zn
2. Domain d1kzyb_: 1kzy B: [73382]
  Other proteins in same PDB: d1kzyc1, d1kzyc2, d1kzyd1, d1kzyd2
  protein/DNA complex; complexed with zn
Domains for 1tsr:
1. Domain d1tsra_: 1tsr A: [22437]
  protein/DNA complex; complexed with zn
2. Domain d1tsrb_: 1tsr B: [22438]
  protein/DNA complex; complexed with zn
3. Domain d1tsrc_: 1tsr C: [22439]
  protein/DNA complex; complexed with zn
Domains for 1tup:
1. Domain d1tupa_: 1tup A: [22434]
  protein/DNA complex; complexed with zn
2. Domain d1tupb_: 1tup B: [22435]
  protein/DNA complex; complexed with zn
3. Domain d1tupc_: 1tup C: [22436]
  protein/DNA complex; complexed with zn
Domains for 1uol:
1. Domain d1uola_: 1uol A: [99695]
  complexed with zn; mutant
2. Domain d1uolb_: 1uol B: [99696]
  complexed with zn; mutant
Domain for 1ycs:
- Domain d1ycsa_: 1ycs A: [22433]
  Other proteins in same PDB: d1ycsb1, d1ycsb2
  complexed with zn
Domain for 2fej:
- Domain d2feja1: 2fej A:96-290 [133349]
  automatically matched to d1uola_
  complexed with zn

Domains for 2h1l:

Domain d2h1lm1: 2h1l M:96-289 [135959]
Other proteins in same PDB: d2h1la1, d2h1lb1, d2h1lc1, d2h1ld1, d2h1le1, d2h1lf1, d2h1lg1, d2h1lh1, d2h1li1, d2h1lj1, d2h1lk1, d2h1ll1
automatically matched to d1uola_
complexed with zn

Domain d2h1ln1: 2h1l N:96-289 [135960]
Other proteins in same PDB: d2h1la1, d2h1lb1, d2h1lc1, d2h1ld1, d2h1le1, d2h1lf1, d2h1lg1, d2h1lh1, d2h1li1, d2h1lj1, d2h1lk1, d2h1ll1
automatically matched to d1uola_
complexed with zn

Domain d2h1lo1: 2h1l O:96-289 [135961]
Other proteins in same PDB: d2h1la1, d2h1lb1, d2h1lc1, d2h1ld1, d2h1le1, d2h1lf1, d2h1lg1, d2h1lh1, d2h1li1, d2h1lj1, d2h1lk1, d2h1ll1
automatically matched to d1uola_
complexed with zn

Domain d2h1lp1: 2h1l P:96-289 [135962]
Other proteins in same PDB: d2h1la1, d2h1lb1, d2h1lc1, d2h1ld1, d2h1le1, d2h1lf1, d2h1lg1, d2h1lh1, d2h1li1, d2h1lj1, d2h1lk1, d2h1ll1
automatically matched to d1uola_
complexed with zn

Domain d2h1lq1: 2h1l Q:96-289 [135963]
Other proteins in same PDB: d2h1la1, d2h1lb1, d2h1lc1, d2h1ld1, d2h1le1, d2h1lf1, d2h1lg1, d2h1lh1, d2h1li1, d2h1lj1, d2h1lk1, d2h1ll1
automatically matched to d1uola_
complexed with zn

Domain d2h1lr1: 2h1l R:96-289 [135964]
Other proteins in same PDB: d2h1la1, d2h1lb1, d2h1lc1, d2h1ld1, d2h1le1, d2h1lf1, d2h1lg1, d2h1lh1, d2h1li1, d2h1lj1, d2h1lk1, d2h1ll1
automatically matched to d1uola_
complexed with zn

Domain d2h1ls1: 2h1l S:96-289 [135965]
Other proteins in same PDB: d2h1la1, d2h1lb1, d2h1lc1, d2h1ld1, d2h1le1, d2h1lf1, d2h1lg1, d2h1lh1, d2h1li1, d2h1lj1, d2h1lk1, d2h1ll1
automatically matched to d1uola_
complexed with zn

Domain d2h1lt1: 2h1l T:96-289 [135966]
Other proteins in same PDB: d2h1la1, d2h1lb1, d2h1lc1, d2h1ld1, d2h1le1, d2h1lf1, d2h1lg1, d2h1lh1, d2h1li1, d2h1lj1, d2h1lk1, d2h1ll1
automatically matched to d1uola_
complexed with zn

Domain d2h1lu1: 2h1l U:96-289 [135967]
Other proteins in same PDB: d2h1la1, d2h1lb1, d2h1lc1, d2h1ld1, d2h1le1, d2h1lf1, d2h1lg1, d2h1lh1, d2h1li1, d2h1lj1, d2h1lk1, d2h1ll1
automatically matched to d1uola_
complexed with zn

Domain d2h1lv1: 2h1l V:96-289 [135968]
Other proteins in same PDB: d2h1la1, d2h1lb1, d2h1lc1, d2h1ld1, d2h1le1, d2h1lf1, d2h1lg1, d2h1lh1, d2h1li1, d2h1lj1, d2h1lk1, d2h1ll1
automatically matched to d1uola_
complexed with zn

Domain d2h1lw1: 2h1l W:96-289 [135969]
Other proteins in same PDB: d2h1la1, d2h1lb1, d2h1lc1, d2h1ld1, d2h1le1, d2h1lf1, d2h1lg1, d2h1lh1, d2h1li1, d2h1lj1, d2h1lk1, d2h1ll1
automatically matched to d1uola_
complexed with zn

Domain d2h1lx1: 2h1l X:96-289 [135970]
Other proteins in same PDB: d2h1la1, d2h1lb1, d2h1lc1, d2h1ld1, d2h1le1, d2h1lf1, d2h1lg1, d2h1lh1, d2h1li1, d2h1lj1, d2h1lk1, d2h1ll1
automatically matched to d1uola_
complexed with zn

Domain for 2pcx:
- Domain d2pcxa_: 2pcx A: [167134]
  automated match to d1gzha_
  complexed with zn
Domain for 2qvq:
- Domain d2qvqa_: 2qvq A: [167840]
  automated match to d1tsra_
  complexed with zn; mutant
Domains for 2qxa:
1. Domain d2qxaa_: 2qxa A: [167853]
  automated match to d1gzha_
  complexed with zn; mutant
2. Domain d2qxab_: 2qxa B: [167854]
  automated match to d1gzha_
  complexed with zn; mutant
3. Domain d2qxac_: 2qxa C: [167855]
  automated match to d1gzha_
  complexed with zn; mutant
4. Domain d2qxad_: 2qxa D: [167856]
  automated match to d1gzha_
  complexed with zn; mutant
Domains for 2qxb:
1. Domain d2qxba_: 2qxb A: [167857]
  automated match to d1gzha_
  complexed with zn; mutant
2. Domain d2qxbb_: 2qxb B: [167858]
  automated match to d1gzha_
  complexed with zn; mutant
3. Domain d2qxbc_: 2qxb C: [167859]
  automated match to d1gzha_
  complexed with zn; mutant
4. Domain d2qxbd_: 2qxb D: [167860]
  automated match to d1gzha_
  complexed with zn; mutant
Domains for 2qxc:
1. Domain d2qxca_: 2qxc A: [167861]
  automated match to d1gzhc_
  complexed with zn; mutant
2. Domain d2qxcb_: 2qxc B: [167862]
  automated match to d1gzhc_
  complexed with zn; mutant
3. Domain d2qxcc_: 2qxc C: [167863]
  automated match to d1gzhc_
  complexed with zn; mutant
4. Domain d2qxcd_: 2qxc D: [167864]
  automated match to d1gzhc_
  complexed with zn; mutant
Domain for 3d05:
- Domain d3d05a_: 3d05 A: [173588]
  automated match to d1gzha_
  complexed with zn; mutant
Domain for 3d06:
- Domain d3d06a_: 3d06 A: [173589]
  automated match to d1gzha_
  complexed with zn; mutant
Domains for 3d07:
1. Domain d3d07a_: 3d07 A: [173590]
  automated match to d1gzha_
  complexed with zn; mutant
2. Domain d3d07b_: 3d07 B: [173591]
  automated match to d1gzha_
  complexed with zn; mutant
Domain for 3d08:
- Domain d3d08a_: 3d08 A: [173592]
  automated match to d1gzha_
  complexed with zn; mutant
Domain for 3d09:
- Domain d3d09a_: 3d09 A: [173593]
  automated match to d1gzha_
  complexed with zn; mutant
Domains for 3d0a:
1. Domain d3d0aa_: 3d0a A: [173594]
  automated match to d1gzha_
  protein/DNA complex; protein/RNA complex; complexed with zn; mutant
2. Domain d3d0ab_: 3d0a B: [173595]
  automated match to d1gzha_
  protein/DNA complex; protein/RNA complex; complexed with zn; mutant
3. Domain d3d0ac_: 3d0a C: [173596]
  automated match to d1gzha_
  protein/DNA complex; protein/RNA complex; complexed with zn; mutant
4. Domain d3d0ad_: 3d0a D: [173597]
  automated match to d1gzha_
  protein/DNA complex; protein/RNA complex; complexed with zn; mutant
Domain for 3igk:
- Domain d3igka_: 3igk A: [178310]
  automated match to d1gzha_
  protein/DNA complex; protein/RNA complex; complexed with zn
Domain for 3igl:
- Domain d3igla_: 3igl A: [178311]
  automated match to d1gzha_
  protein/DNA complex; protein/RNA complex; complexed with edo, zn
Domains for 3kz8:
1. Domain d3kz8a_: 3kz8 A: [179824]
  automated match to d1gzha_
  protein/DNA complex; complexed with iod, zn
2. Domain d3kz8b_: 3kz8 B: [179825]
  automated match to d1gzha_
  protein/DNA complex; complexed with iod, zn

Mouse (Mus musculus) [TaxId:10090] [63683] (1 PDB entry)
- Domains for 1hu8:
  1. Domain d1hu8a_: 1hu8 A: [61269]
    complexed with zn
  2. Domain d1hu8b_: 1hu8 B: [61270]
    complexed with zn
  3. Domain d1hu8c_: 1hu8 C: [61271]
    complexed with zn

More info for Protein p53 tumor suppressor, DNA-binding domain from b.2.5.2: p53 DNA-binding domain-like

Timeline for Protein p53 tumor suppressor, DNA-binding domain from b.2.5.2: p53 DNA-binding domain-like:

Protein p53 tumor suppressor, DNA-binding domain from b.2.5.2: p53 DNA-binding domain-like first appeared (with stable ids) in SCOP 1.55, called Protein p53 tumor suppressor, DNA-binding domain from b.2.5.1: p53-like transcription factors
Protein p53 tumor suppressor, DNA-binding domain from b.2.5.2: p53 DNA-binding domain-like appears in SCOPe 2.01
Protein p53 tumor suppressor, DNA-binding domain from b.2.5.2: p53 DNA-binding domain-like appears in SCOPe 2.03
Protein p53 tumor suppressor, DNA-binding domain from b.2.5.2: p53 DNA-binding domain-like appears in the current release, SCOPe 2.08