SCOPe 2.02: Domain d3kz8a_: 3kz8 A:

Lineage for d3kz8a_ (3kz8 A:)

1. Root: SCOPe 2.02

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.2: Common fold of diphtheria toxin/transcription factors/cytochrome f [49379] (10 superfamilies)
   sandwich; 9 strands in 2 sheet; greek-key; subclass of immunoglobin-like fold

4. Superfamily b.2.5: p53-like transcription factors [49417] (7 families)

5. Family b.2.5.2: p53 DNA-binding domain-like [81314] (3 proteins)

6. Protein p53 tumor suppressor, DNA-binding domain [49419] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [49420] (22 PDB entries)

8. Domain d3kz8a_: 3kz8 A: [179824]
   automated match to d1gzha_
   protein/DNA complex; complexed with iod, zn

Details for d3kz8a_

PDB Entry: 3kz8, 1.91 Å

PDB Description: Diversity in DNA recognition by p53 revealed by crystal structures with Hoogsteen base pairs (p53-DNA complex 3)

PDB Compounds: (A:) Cellular tumor antigen p53

SCOPe Domain Sequences for d3kz8a_:

Sequence, based on SEQRES records:

>d3kz8a_ b.2.5.2 (A:) p53 tumor suppressor, DNA-binding domain {Human (Homo sapiens) [TaxId: 9606]}
ssvpsqktyqgsygfrlgflhsgtaksvtctyspalnkmfcqlaktcpvqlwvdstpppg
trvramaiykqsqhmtevvrrcphhercsdsdglappqhlirvegnlrveylddrntfrh
svvvpyeppevgsdcttihynymcnsscmggmnrrpiltiitledssgnllgrnsfevrv
cacpgrdrrteeenlrkk

Sequence, based on observed residues (ATOM records):

>d3kz8a_ b.2.5.2 (A:) p53 tumor suppressor, DNA-binding domain {Human (Homo sapiens) [TaxId: 9606]}
ssvpsqktyqgsygfrlgflhsgtaksvtctyspalnkmfcqlaktcpvqlwvdstpppg
trvramaiykqsqhmtevvrrcphhercsdlappqhlirvegnlrveylddrntfrhsvv
vpyeppevgsdcttihynymcnsscmggmnrrpiltiitledssgnllgrnsfevrvcac
pgrdrrteeenlrkk

Timeline for d3kz8a_:

• d3kz8a_ first appeared in SCOPe 2.01
  
• d3kz8a_ appears in SCOPe 2.03
  
• d3kz8a_ appears in the current release, SCOPe 2.08