PDB entry 2qvq
View 2qvq on RCSB PDB site
Description: Human p53 Core Domain Mutant V157F/N235K/N239Y
Class: antitumor protein
Keywords: Tumor suppressor, p53, cancer, cancer mutation, suppressor mutation, Acetylation, Activator, Alternative splicing, Anti-oncogene, Apoptosis, Cell cycle, Cytoplasm, Disease mutation, DNA-binding, Endoplasmic reticulum, Glycoprotein, Host-virus interaction, Li-Fraumeni syndrome, Metal-binding, Nucleus, Phosphorylation, Polymorphism, Transcription, Transcription regulation, Ubl conjugation, Zinc, ANTITUMOR PROTEIN
Deposited on
2007-08-08, released
2008-11-04
The last revision prior to the SCOPe 2.02 freeze date was dated
2009-11-17, with a file datestamp of
2009-11-13.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.239
AEROSPACI score: 0.4
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Cellular tumor antigen p53
Species: Homo sapiens [TaxId:9606]
Gene: TP53, P53
Database cross-references and differences (RAF-indexed):
- Uniprot P04637 (0-195)
- engineered (63)
- engineered (141)
- engineered (145)
Domains in SCOPe 2.02: d2qvqa_ - Heterogens: ZN, HOH