Lineage for Protein: p53 tumor suppressor, DNA-binding domain

  1. Root: SCOPe 2.07
  2. 2344607Class b: All beta proteins [48724] (178 folds)
  3. 2363595Fold b.2: Common fold of diphtheria toxin/transcription factors/cytochrome f [49379] (9 superfamilies)
    sandwich; 9 strands in 2 sheet; greek-key; subclass of immunoglobin-like fold
  4. 2364216Superfamily b.2.5: p53-like transcription factors [49417] (8 families) (S)
  5. 2364217Family b.2.5.2: p53 DNA-binding domain-like [81314] (3 proteins)
  6. 2364218Protein p53 tumor suppressor, DNA-binding domain [49419] (2 species)

Species:

  1. 2364219Human (Homo sapiens) [TaxId:9606] [49420] (50 PDB entries)
    1. Domains for 1gzh:
      1. 2364303Domain d1gzha_: 1gzh A: [70807]
        Other proteins in same PDB: d1gzhb1, d1gzhb2, d1gzhd1, d1gzhd2
        complexed with so4, zn
      2. 2364304Domain d1gzhc_: 1gzh C: [70810]
        Other proteins in same PDB: d1gzhb1, d1gzhb2, d1gzhd1, d1gzhd2
        complexed with so4, zn
    2. Domains for 1kzy:
      1. 2364294Domain d1kzya_: 1kzy A: [73381]
        Other proteins in same PDB: d1kzyc1, d1kzyc2, d1kzyd1, d1kzyd2
        protein/DNA complex; complexed with zn
      2. 2364295Domain d1kzyb_: 1kzy B: [73382]
        Other proteins in same PDB: d1kzyc1, d1kzyc2, d1kzyd1, d1kzyd2
        protein/DNA complex; complexed with zn
    3. Domains for 1tsr:
      1. 2364287Domain d1tsra_: 1tsr A: [22437]
        protein/DNA complex; complexed with zn
      2. 2364288Domain d1tsrb_: 1tsr B: [22438]
        protein/DNA complex; complexed with zn
      3. 2364289Domain d1tsrc_: 1tsr C: [22439]
        protein/DNA complex; complexed with zn
    4. Domains for 1tup:
      1. 2364284Domain d1tupa_: 1tup A: [22434]
        protein/DNA complex; complexed with zn
      2. 2364285Domain d1tupb_: 1tup B: [22435]
        protein/DNA complex; complexed with zn
      3. 2364286Domain d1tupc_: 1tup C: [22436]
        protein/DNA complex; complexed with zn
    5. Domains for 1uol:
      1. 2364243Domain d1uola_: 1uol A: [99695]
        complexed with zn; mutant
      2. 2364244Domain d1uolb_: 1uol B: [99696]
        complexed with zn; mutant
    6. Domain for 1ycs:
    7. Domain for 2fej:
    8. Domains for 2h1l:
      1. 2364305Domain d2h1lm2: 2h1l M:92-289 [135959]
        Other proteins in same PDB: d2h1la_, d2h1lb_, d2h1lc_, d2h1ld_, d2h1le_, d2h1lf_, d2h1lg_, d2h1lh_, d2h1li_, d2h1lj_, d2h1lk_, d2h1ll_, d2h1lm3, d2h1ln3, d2h1lo3, d2h1lp3, d2h1lq3, d2h1lr3, d2h1ls3, d2h1lt3, d2h1lu3, d2h1lv3, d2h1lw3, d2h1lx3
        automated match to d3kmda_
        complexed with zn
      2. 2364306Domain d2h1ln2: 2h1l N:92-289 [135960]
        Other proteins in same PDB: d2h1la_, d2h1lb_, d2h1lc_, d2h1ld_, d2h1le_, d2h1lf_, d2h1lg_, d2h1lh_, d2h1li_, d2h1lj_, d2h1lk_, d2h1ll_, d2h1lm3, d2h1ln3, d2h1lo3, d2h1lp3, d2h1lq3, d2h1lr3, d2h1ls3, d2h1lt3, d2h1lu3, d2h1lv3, d2h1lw3, d2h1lx3
        automated match to d3kmda_
        complexed with zn
      3. 2364307Domain d2h1lo2: 2h1l O:92-289 [135961]
        Other proteins in same PDB: d2h1la_, d2h1lb_, d2h1lc_, d2h1ld_, d2h1le_, d2h1lf_, d2h1lg_, d2h1lh_, d2h1li_, d2h1lj_, d2h1lk_, d2h1ll_, d2h1lm3, d2h1ln3, d2h1lo3, d2h1lp3, d2h1lq3, d2h1lr3, d2h1ls3, d2h1lt3, d2h1lu3, d2h1lv3, d2h1lw3, d2h1lx3
        automated match to d3kmda_
        complexed with zn
      4. 2364308Domain d2h1lp2: 2h1l P:92-289 [135962]
        Other proteins in same PDB: d2h1la_, d2h1lb_, d2h1lc_, d2h1ld_, d2h1le_, d2h1lf_, d2h1lg_, d2h1lh_, d2h1li_, d2h1lj_, d2h1lk_, d2h1ll_, d2h1lm3, d2h1ln3, d2h1lo3, d2h1lp3, d2h1lq3, d2h1lr3, d2h1ls3, d2h1lt3, d2h1lu3, d2h1lv3, d2h1lw3, d2h1lx3
        automated match to d3kmda_
        complexed with zn
      5. 2364309Domain d2h1lq2: 2h1l Q:92-289 [135963]
        Other proteins in same PDB: d2h1la_, d2h1lb_, d2h1lc_, d2h1ld_, d2h1le_, d2h1lf_, d2h1lg_, d2h1lh_, d2h1li_, d2h1lj_, d2h1lk_, d2h1ll_, d2h1lm3, d2h1ln3, d2h1lo3, d2h1lp3, d2h1lq3, d2h1lr3, d2h1ls3, d2h1lt3, d2h1lu3, d2h1lv3, d2h1lw3, d2h1lx3
        automated match to d3kmda_
        complexed with zn
      6. 2364310Domain d2h1lr2: 2h1l R:92-289 [135964]
        Other proteins in same PDB: d2h1la_, d2h1lb_, d2h1lc_, d2h1ld_, d2h1le_, d2h1lf_, d2h1lg_, d2h1lh_, d2h1li_, d2h1lj_, d2h1lk_, d2h1ll_, d2h1lm3, d2h1ln3, d2h1lo3, d2h1lp3, d2h1lq3, d2h1lr3, d2h1ls3, d2h1lt3, d2h1lu3, d2h1lv3, d2h1lw3, d2h1lx3
        automated match to d3kmda_
        complexed with zn
      7. 2364311Domain d2h1ls2: 2h1l S:92-289 [135965]
        Other proteins in same PDB: d2h1la_, d2h1lb_, d2h1lc_, d2h1ld_, d2h1le_, d2h1lf_, d2h1lg_, d2h1lh_, d2h1li_, d2h1lj_, d2h1lk_, d2h1ll_, d2h1lm3, d2h1ln3, d2h1lo3, d2h1lp3, d2h1lq3, d2h1lr3, d2h1ls3, d2h1lt3, d2h1lu3, d2h1lv3, d2h1lw3, d2h1lx3
        automated match to d3kmda_
        complexed with zn
      8. 2364312Domain d2h1lt2: 2h1l T:92-289 [135966]
        Other proteins in same PDB: d2h1la_, d2h1lb_, d2h1lc_, d2h1ld_, d2h1le_, d2h1lf_, d2h1lg_, d2h1lh_, d2h1li_, d2h1lj_, d2h1lk_, d2h1ll_, d2h1lm3, d2h1ln3, d2h1lo3, d2h1lp3, d2h1lq3, d2h1lr3, d2h1ls3, d2h1lt3, d2h1lu3, d2h1lv3, d2h1lw3, d2h1lx3
        automated match to d3kmda_
        complexed with zn
      9. 2364313Domain d2h1lu2: 2h1l U:92-289 [135967]
        Other proteins in same PDB: d2h1la_, d2h1lb_, d2h1lc_, d2h1ld_, d2h1le_, d2h1lf_, d2h1lg_, d2h1lh_, d2h1li_, d2h1lj_, d2h1lk_, d2h1ll_, d2h1lm3, d2h1ln3, d2h1lo3, d2h1lp3, d2h1lq3, d2h1lr3, d2h1ls3, d2h1lt3, d2h1lu3, d2h1lv3, d2h1lw3, d2h1lx3
        automated match to d3kmda_
        complexed with zn
      10. 2364314Domain d2h1lv2: 2h1l V:92-289 [135968]
        Other proteins in same PDB: d2h1la_, d2h1lb_, d2h1lc_, d2h1ld_, d2h1le_, d2h1lf_, d2h1lg_, d2h1lh_, d2h1li_, d2h1lj_, d2h1lk_, d2h1ll_, d2h1lm3, d2h1ln3, d2h1lo3, d2h1lp3, d2h1lq3, d2h1lr3, d2h1ls3, d2h1lt3, d2h1lu3, d2h1lv3, d2h1lw3, d2h1lx3
        automated match to d3kmda_
        complexed with zn
      11. 2364315Domain d2h1lw2: 2h1l W:92-289 [135969]
        Other proteins in same PDB: d2h1la_, d2h1lb_, d2h1lc_, d2h1ld_, d2h1le_, d2h1lf_, d2h1lg_, d2h1lh_, d2h1li_, d2h1lj_, d2h1lk_, d2h1ll_, d2h1lm3, d2h1ln3, d2h1lo3, d2h1lp3, d2h1lq3, d2h1lr3, d2h1ls3, d2h1lt3, d2h1lu3, d2h1lv3, d2h1lw3, d2h1lx3
        automated match to d3kmda_
        complexed with zn
      12. 2364316Domain d2h1lx2: 2h1l X:92-289 [135970]
        Other proteins in same PDB: d2h1la_, d2h1lb_, d2h1lc_, d2h1ld_, d2h1le_, d2h1lf_, d2h1lg_, d2h1lh_, d2h1li_, d2h1lj_, d2h1lk_, d2h1ll_, d2h1lm3, d2h1ln3, d2h1lo3, d2h1lp3, d2h1lq3, d2h1lr3, d2h1ls3, d2h1lt3, d2h1lu3, d2h1lv3, d2h1lw3, d2h1lx3
        automated match to d3kmda_
        complexed with zn
    9. Domain for 2mej:
    10. Domain for 2pcx:
    11. Domain for 2qvq:
    12. Domains for 2qxa:
      1. 2364229Domain d2qxaa_: 2qxa A: [304439]
        automated match to d4kvpc_
        complexed with zn; mutant
      2. 2364230Domain d2qxab_: 2qxa B: [304440]
        automated match to d4kvpc_
        complexed with zn; mutant
      3. 2364231Domain d2qxac_: 2qxa C: [304441]
        automated match to d4kvpc_
        complexed with zn; mutant
      4. 2364232Domain d2qxad_: 2qxa D: [304442]
        automated match to d4kvpc_
        complexed with zn; mutant
    13. Domains for 2qxb:
      1. 2364290Domain d2qxba_: 2qxb A: [304443]
        automated match to d2ac0a_
        complexed with zn; mutant
      2. 2364291Domain d2qxbb_: 2qxb B: [304444]
        automated match to d2ac0a_
        complexed with zn; mutant
      3. 2364292Domain d2qxbc_: 2qxb C: [304445]
        automated match to d2ac0a_
        complexed with zn; mutant
      4. 2364293Domain d2qxbd_: 2qxb D: [304446]
        automated match to d2ac0a_
        complexed with zn; mutant
    14. Domains for 2qxc:
      1. 2364263Domain d2qxca_: 2qxc A: [304447]
        automated match to d3igla_
        complexed with zn; mutant
      2. 2364264Domain d2qxcb_: 2qxc B: [304448]
        automated match to d3igla_
        complexed with zn; mutant
      3. 2364265Domain d2qxcc_: 2qxc C: [304449]
        automated match to d3igla_
        complexed with zn; mutant
      4. 2364266Domain d2qxcd_: 2qxc D: [304450]
        automated match to d3igla_
        complexed with zn; mutant
    15. Domain for 3d05:
    16. Domain for 3d06:
    17. Domains for 3d07:
      1. 2364253Domain d3d07a_: 3d07 A: [173590]
        automated match to d1gzha_
        complexed with zn; mutant
      2. 2364254Domain d3d07b_: 3d07 B: [173591]
        automated match to d1gzha_
        complexed with zn; mutant
    18. Domain for 3d08:
    19. Domain for 3d09:
    20. Domains for 3d0a:
      1. 2364237Domain d3d0aa_: 3d0a A: [173594]
        automated match to d1gzha_
        protein/DNA complex; protein/RNA complex; complexed with zn; mutant
      2. 2364238Domain d3d0ab_: 3d0a B: [173595]
        automated match to d1gzha_
        protein/DNA complex; protein/RNA complex; complexed with zn; mutant
      3. 2364239Domain d3d0ac_: 3d0a C: [173596]
        automated match to d1gzha_
        protein/DNA complex; protein/RNA complex; complexed with zn; mutant
      4. 2364240Domain d3d0ad_: 3d0a D: [173597]
        automated match to d1gzha_
        protein/DNA complex; protein/RNA complex; complexed with zn; mutant
    21. Domain for 3igk:
      • 2364224Domain d3igka_: 3igk A: [178310]
        automated match to d1gzha_
        protein/DNA complex; protein/RNA complex; complexed with zn
    22. Domain for 3igl:
      • 2364233Domain d3igla_: 3igl A: [178311]
        automated match to d1gzha_
        protein/DNA complex; protein/RNA complex; complexed with edo, zn
    23. Domains for 3kz8:
      1. 2364246Domain d3kz8a_: 3kz8 A: [179824]
        automated match to d1gzha_
        protein/DNA complex; complexed with iod, zn
      2. 2364247Domain d3kz8b_: 3kz8 B: [179825]
        automated match to d1gzha_
        protein/DNA complex; complexed with iod, zn
    24. Domains for 4ibq:
      1. 2364275Domain d4ibqa_: 4ibq A: [223098]
        automated match to d2ahia_
        complexed with act, edo, zn; mutant
      2. 2364276Domain d4ibqb_: 4ibq B: [223099]
        automated match to d2ahia_
        complexed with act, edo, zn; mutant
      3. 2364277Domain d4ibqc_: 4ibq C: [223100]
        automated match to d2ahia_
        complexed with act, edo, zn; mutant
      4. 2364278Domain d4ibqd_: 4ibq D: [223101]
        automated match to d2ahia_
        complexed with act, edo, zn; mutant
    25. Domains for 4ibs:
      1. 2364269Domain d4ibsa_: 4ibs A: [223102]
        automated match to d2ahia_
        complexed with edo, zn; mutant
      2. 2364270Domain d4ibsb_: 4ibs B: [223103]
        automated match to d2ahia_
        complexed with edo, zn; mutant
      3. 2364271Domain d4ibsc_: 4ibs C: [223104]
        automated match to d2ahia_
        complexed with edo, zn; mutant
      4. 2364272Domain d4ibsd_: 4ibs D: [223105]
        automated match to d2ahia_
        complexed with edo, zn; mutant
    26. Domains for 4ibt:
      1. 2364259Domain d4ibta_: 4ibt A: [223106]
        automated match to d2ahia_
        complexed with zn; mutant
      2. 2364260Domain d4ibtb_: 4ibt B: [223107]
        automated match to d2ahia_
        complexed with zn; mutant
      3. 2364261Domain d4ibtc_: 4ibt C: [223108]
        automated match to d2ahia_
        complexed with zn; mutant
      4. 2364262Domain d4ibtd_: 4ibt D: [223109]
        automated match to d2ahia_
        complexed with zn; mutant
    27. Domains for 4ibu:
      1. 2364255Domain d4ibua_: 4ibu A: [223110]
        automated match to d2ahia_
        protein/DNA complex; complexed with act, edo, zn; mutant
      2. 2364256Domain d4ibub_: 4ibu B: [223111]
        automated match to d2ahia_
        protein/DNA complex; complexed with act, edo, zn; mutant
      3. 2364257Domain d4ibuc_: 4ibu C: [223112]
        automated match to d2ahia_
        protein/DNA complex; complexed with act, edo, zn; mutant
      4. 2364258Domain d4ibud_: 4ibu D: [223113]
        automated match to d2ahia_
        protein/DNA complex; complexed with act, edo, zn; mutant
    28. Domain for 4ibv:
    29. Domain for 4ibw:
    30. Domains for 4iby:
      1. 2364241Domain d4ibya_: 4iby A: [223116]
        automated match to d2ahia_
        complexed with edo, zn; mutant
      2. 2364242Domain d4ibyb_: 4iby B: [223117]
        automated match to d2ahia_
        complexed with edo, zn; mutant
    31. Domains for 4ibz:
      1. 2364280Domain d4ibza_: 4ibz A: [223118]
        automated match to d2ahia_
        complexed with act, edo, zn; mutant
      2. 2364281Domain d4ibzb_: 4ibz B: [223119]
        automated match to d2ahia_
        complexed with act, edo, zn; mutant
      3. 2364282Domain d4ibzc_: 4ibz C: [223120]
        automated match to d2ahia_
        complexed with act, edo, zn; mutant
      4. 2364283Domain d4ibzd_: 4ibz D: [223121]
        automated match to d2ahia_
        complexed with act, edo, zn; mutant
    32. Domain for 4ijt:
    33. Domains for 4kvp:
      1. 2364225Domain d4kvpa_: 4kvp A: [224494]
        complexed with zn; mutant
      2. 2364226Domain d4kvpb_: 4kvp B: [224495]
        complexed with zn; mutant
      3. 2364227Domain d4kvpc_: 4kvp C: [224496]
        complexed with zn; mutant
      4. 2364228Domain d4kvpd_: 4kvp D: [224497]
        complexed with zn; mutant
    34. Domains for 4lo9:
      1. 2364297Domain d4lo9a_: 4lo9 A: [224722]
        complexed with zn; mutant
      2. 2364298Domain d4lo9b_: 4lo9 B: [224723]
        complexed with zn; mutant
      3. 2364299Domain d4lo9c_: 4lo9 C: [224724]
        complexed with zn; mutant
      4. 2364300Domain d4lo9d_: 4lo9 D: [224725]
        complexed with zn; mutant
    35. Domains for 4loe:
      1. 2364249Domain d4loea_: 4loe A: [224726]
        complexed with zn; mutant
      2. 2364250Domain d4loeb_: 4loe B: [224727]
        complexed with zn; mutant
      3. 2364251Domain d4loec_: 4loe C: [224728]
        complexed with zn; mutant
      4. 2364252Domain d4loed_: 4loe D: [224729]
        complexed with zn; mutant
    36. Domain for 4lof:
    37. Domain for 4mzi:
    38. Domain for 4qo1:
    39. Domains for 4xr8:
      1. 2364301Domain d4xr8c_: 4xr8 C: [311849]
        automated match to d1ycsa_
        complexed with edo, mal, peg, zn
      2. 2364302Domain d4xr8d_: 4xr8 D: [311729]
        automated match to d1ycsa_
        complexed with edo, mal, peg, zn
    40. Domains for 5lap:
      1. 2364234Domain d5lapa_: 5lap A: [321140]
        automated match to d2feja_
        complexed with 6sm, zn; mutant
      2. 2364235Domain d5lapb_: 5lap B: [321131]
        automated match to d2feja_
        complexed with 6sm, zn; mutant
    41. Domains for 5o1a:
      1. 3051818Domain d5o1aa_: 5o1a A: [351880]
        automated match to d2feja_
        protein/DNA complex; complexed with 9h5, gol, zn; mutant
      2. 3051834Domain d5o1ab_: 5o1a B: [351896]
        automated match to d2feja_
        protein/DNA complex; complexed with 9h5, gol, zn; mutant
    42. Domains for 5o1b:
      1. 3051817Domain d5o1ba_: 5o1b A: [351879]
        automated match to d2feja_
        protein/DNA complex; complexed with 9h2, gol, zn; mutant
      2. 3051871Domain d5o1bb_: 5o1b B: [351933]
        automated match to d2feja_
        protein/DNA complex; complexed with 9h2, gol, zn; mutant
    43. Domains for 5o1c:
      1. 3051810Domain d5o1ca_: 5o1c A: [351872]
        automated match to d2feja_
        protein/DNA complex; complexed with 9gz, zn; mutant
      2. 3051824Domain d5o1cb_: 5o1c B: [351886]
        automated match to d2feja_
        protein/DNA complex; complexed with 9gz, zn; mutant
    44. Domains for 5o1d:
      1. 3051809Domain d5o1db_: 5o1d B: [351871]
        automated match to d2feja_
        protein/DNA complex; complexed with 9gw, gol, zn; mutant
      2. 3051906Domain d5o1da_: 5o1d A: [351968]
        automated match to d2feja_
        protein/DNA complex; complexed with 9gw, gol, zn; mutant
    45. Domains for 5o1e:
      1. 3051831Domain d5o1ea_: 5o1e A: [351893]
        automated match to d2feja_
        protein/DNA complex; complexed with 9gt, gol, zn; mutant
      2. 3051873Domain d5o1eb_: 5o1e B: [351935]
        automated match to d2feja_
        protein/DNA complex; complexed with 9gt, gol, zn; mutant
    46. Domains for 5o1f:
      1. 3051839Domain d5o1fa_: 5o1f A: [351901]
        automated match to d2feja_
        protein/DNA complex; complexed with 9gq, zn; mutant
      2. 3051843Domain d5o1fb_: 5o1f B: [351905]
        automated match to d2feja_
        protein/DNA complex; complexed with 9gq, zn; mutant
    47. Domains for 5o1g:
      1. 3051842Domain d5o1gb_: 5o1g B: [351904]
        automated match to d2feja_
        protein/DNA complex; complexed with 9gk, gol, zn; mutant
      2. 3051846Domain d5o1ga_: 5o1g A: [351908]
        automated match to d2feja_
        protein/DNA complex; complexed with 9gk, gol, zn; mutant
    48. Domains for 5o1h:
      1. 3051838Domain d5o1hb_: 5o1h B: [351900]
        automated match to d2feja_
        protein/DNA complex; complexed with 9gn, gol, zn; mutant
      2. 3051904Domain d5o1ha_: 5o1h A: [351966]
        automated match to d2feja_
        protein/DNA complex; complexed with 9gn, gol, zn; mutant
    49. Domains for 5o1i:
      1. 3051833Domain d5o1ib_: 5o1i B: [351895]
        automated match to d2feja_
        protein/DNA complex; complexed with 9gh, edo, gol, zn; mutant
      2. 3051953Domain d5o1ia_: 5o1i A: [352015]
        automated match to d2feja_
        protein/DNA complex; complexed with 9gh, edo, gol, zn; mutant
    50. Domains for 6ff9:
      1. 3051392Domain d6ff9a_: 6ff9 A: [351454]
        automated match to d4xr8c_
        complexed with zn; mutant
      2. 3051395Domain d6ff9b_: 6ff9 B: [351457]
        automated match to d4xr8c_
        complexed with zn; mutant
      3. 3051396Domain d6ff9c_: 6ff9 C: [351458]
        automated match to d4xr8c_
        complexed with zn; mutant
      4. 3051527Domain d6ff9d_: 6ff9 D: [351589]
        automated match to d4xr8c_
        complexed with zn; mutant
  2. 2364319Mouse (Mus musculus) [TaxId:10090] [63683] (1 PDB entry)

More info for Protein p53 tumor suppressor, DNA-binding domain from b.2.5.2: p53 DNA-binding domain-like

Timeline for Protein p53 tumor suppressor, DNA-binding domain from b.2.5.2: p53 DNA-binding domain-like: