Lineage for Protein: p53 tumor suppressor, DNA-binding domain

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2033752Fold b.2: Common fold of diphtheria toxin/transcription factors/cytochrome f [49379] (9 superfamilies)
    sandwich; 9 strands in 2 sheet; greek-key; subclass of immunoglobin-like fold
  4. 2034243Superfamily b.2.5: p53-like transcription factors [49417] (8 families) (S)
  5. 2034244Family b.2.5.2: p53 DNA-binding domain-like [81314] (3 protein domains)
  6. 2034245Protein p53 tumor suppressor, DNA-binding domain [49419] (2 species)

Species:

  1. 2034246Human (Homo sapiens) [TaxId:9606] [49420] (40 PDB entries)
    1. Domains for 1gzh:
      1. 2034326Domain d1gzha_: 1gzh A: [70807]
        Other proteins in same PDB: d1gzhb1, d1gzhb2, d1gzhd1, d1gzhd2
        complexed with so4, zn
      2. 2034327Domain d1gzhc_: 1gzh C: [70810]
        Other proteins in same PDB: d1gzhb1, d1gzhb2, d1gzhd1, d1gzhd2
        complexed with so4, zn
    2. Domains for 1kzy:
      1. 2034320Domain d1kzya_: 1kzy A: [73381]
        Other proteins in same PDB: d1kzyc1, d1kzyc2, d1kzyd1, d1kzyd2
        protein/DNA complex; complexed with zn
      2. 2034321Domain d1kzyb_: 1kzy B: [73382]
        Other proteins in same PDB: d1kzyc1, d1kzyc2, d1kzyd1, d1kzyd2
        protein/DNA complex; complexed with zn
    3. Domains for 1tsr:
      1. 2034313Domain d1tsra_: 1tsr A: [22437]
        protein/DNA complex; complexed with zn
      2. 2034314Domain d1tsrb_: 1tsr B: [22438]
        protein/DNA complex; complexed with zn
      3. 2034315Domain d1tsrc_: 1tsr C: [22439]
        protein/DNA complex; complexed with zn
    4. Domains for 1tup:
      1. 2034310Domain d1tupa_: 1tup A: [22434]
        protein/DNA complex; complexed with zn
      2. 2034311Domain d1tupb_: 1tup B: [22435]
        protein/DNA complex; complexed with zn
      3. 2034312Domain d1tupc_: 1tup C: [22436]
        protein/DNA complex; complexed with zn
    5. Domains for 1uol:
      1. 2034272Domain d1uola_: 1uol A: [99695]
        complexed with zn; mutant
      2. 2034273Domain d1uolb_: 1uol B: [99696]
        complexed with zn; mutant
    6. Domain for 1ycs:
    7. Domain for 2fej:
    8. Domains for 2h1l:
      1. 2034328Domain d2h1lm2: 2h1l M:92-289 [135959]
        Other proteins in same PDB: d2h1la_, d2h1lb_, d2h1lc_, d2h1ld_, d2h1le_, d2h1lf_, d2h1lg_, d2h1lh_, d2h1li_, d2h1lj_, d2h1lk_, d2h1ll_, d2h1lm3, d2h1ln3, d2h1lo3, d2h1lp3, d2h1lq3, d2h1lr3, d2h1ls3, d2h1lt3, d2h1lu3, d2h1lv3, d2h1lw3, d2h1lx3
        automated match to d3kmda_
        complexed with zn
      2. 2034329Domain d2h1ln2: 2h1l N:92-289 [135960]
        Other proteins in same PDB: d2h1la_, d2h1lb_, d2h1lc_, d2h1ld_, d2h1le_, d2h1lf_, d2h1lg_, d2h1lh_, d2h1li_, d2h1lj_, d2h1lk_, d2h1ll_, d2h1lm3, d2h1ln3, d2h1lo3, d2h1lp3, d2h1lq3, d2h1lr3, d2h1ls3, d2h1lt3, d2h1lu3, d2h1lv3, d2h1lw3, d2h1lx3
        automated match to d3kmda_
        complexed with zn
      3. 2034330Domain d2h1lo2: 2h1l O:92-289 [135961]
        Other proteins in same PDB: d2h1la_, d2h1lb_, d2h1lc_, d2h1ld_, d2h1le_, d2h1lf_, d2h1lg_, d2h1lh_, d2h1li_, d2h1lj_, d2h1lk_, d2h1ll_, d2h1lm3, d2h1ln3, d2h1lo3, d2h1lp3, d2h1lq3, d2h1lr3, d2h1ls3, d2h1lt3, d2h1lu3, d2h1lv3, d2h1lw3, d2h1lx3
        automated match to d3kmda_
        complexed with zn
      4. 2034331Domain d2h1lp2: 2h1l P:92-289 [135962]
        Other proteins in same PDB: d2h1la_, d2h1lb_, d2h1lc_, d2h1ld_, d2h1le_, d2h1lf_, d2h1lg_, d2h1lh_, d2h1li_, d2h1lj_, d2h1lk_, d2h1ll_, d2h1lm3, d2h1ln3, d2h1lo3, d2h1lp3, d2h1lq3, d2h1lr3, d2h1ls3, d2h1lt3, d2h1lu3, d2h1lv3, d2h1lw3, d2h1lx3
        automated match to d3kmda_
        complexed with zn
      5. 2034332Domain d2h1lq2: 2h1l Q:92-289 [135963]
        Other proteins in same PDB: d2h1la_, d2h1lb_, d2h1lc_, d2h1ld_, d2h1le_, d2h1lf_, d2h1lg_, d2h1lh_, d2h1li_, d2h1lj_, d2h1lk_, d2h1ll_, d2h1lm3, d2h1ln3, d2h1lo3, d2h1lp3, d2h1lq3, d2h1lr3, d2h1ls3, d2h1lt3, d2h1lu3, d2h1lv3, d2h1lw3, d2h1lx3
        automated match to d3kmda_
        complexed with zn
      6. 2034333Domain d2h1lr2: 2h1l R:92-289 [135964]
        Other proteins in same PDB: d2h1la_, d2h1lb_, d2h1lc_, d2h1ld_, d2h1le_, d2h1lf_, d2h1lg_, d2h1lh_, d2h1li_, d2h1lj_, d2h1lk_, d2h1ll_, d2h1lm3, d2h1ln3, d2h1lo3, d2h1lp3, d2h1lq3, d2h1lr3, d2h1ls3, d2h1lt3, d2h1lu3, d2h1lv3, d2h1lw3, d2h1lx3
        automated match to d3kmda_
        complexed with zn
      7. 2034334Domain d2h1ls2: 2h1l S:92-289 [135965]
        Other proteins in same PDB: d2h1la_, d2h1lb_, d2h1lc_, d2h1ld_, d2h1le_, d2h1lf_, d2h1lg_, d2h1lh_, d2h1li_, d2h1lj_, d2h1lk_, d2h1ll_, d2h1lm3, d2h1ln3, d2h1lo3, d2h1lp3, d2h1lq3, d2h1lr3, d2h1ls3, d2h1lt3, d2h1lu3, d2h1lv3, d2h1lw3, d2h1lx3
        automated match to d3kmda_
        complexed with zn
      8. 2034335Domain d2h1lt2: 2h1l T:92-289 [135966]
        Other proteins in same PDB: d2h1la_, d2h1lb_, d2h1lc_, d2h1ld_, d2h1le_, d2h1lf_, d2h1lg_, d2h1lh_, d2h1li_, d2h1lj_, d2h1lk_, d2h1ll_, d2h1lm3, d2h1ln3, d2h1lo3, d2h1lp3, d2h1lq3, d2h1lr3, d2h1ls3, d2h1lt3, d2h1lu3, d2h1lv3, d2h1lw3, d2h1lx3
        automated match to d3kmda_
        complexed with zn
      9. 2034336Domain d2h1lu2: 2h1l U:92-289 [135967]
        Other proteins in same PDB: d2h1la_, d2h1lb_, d2h1lc_, d2h1ld_, d2h1le_, d2h1lf_, d2h1lg_, d2h1lh_, d2h1li_, d2h1lj_, d2h1lk_, d2h1ll_, d2h1lm3, d2h1ln3, d2h1lo3, d2h1lp3, d2h1lq3, d2h1lr3, d2h1ls3, d2h1lt3, d2h1lu3, d2h1lv3, d2h1lw3, d2h1lx3
        automated match to d3kmda_
        complexed with zn
      10. 2034337Domain d2h1lv2: 2h1l V:92-289 [135968]
        Other proteins in same PDB: d2h1la_, d2h1lb_, d2h1lc_, d2h1ld_, d2h1le_, d2h1lf_, d2h1lg_, d2h1lh_, d2h1li_, d2h1lj_, d2h1lk_, d2h1ll_, d2h1lm3, d2h1ln3, d2h1lo3, d2h1lp3, d2h1lq3, d2h1lr3, d2h1ls3, d2h1lt3, d2h1lu3, d2h1lv3, d2h1lw3, d2h1lx3
        automated match to d3kmda_
        complexed with zn
      11. 2034338Domain d2h1lw2: 2h1l W:92-289 [135969]
        Other proteins in same PDB: d2h1la_, d2h1lb_, d2h1lc_, d2h1ld_, d2h1le_, d2h1lf_, d2h1lg_, d2h1lh_, d2h1li_, d2h1lj_, d2h1lk_, d2h1ll_, d2h1lm3, d2h1ln3, d2h1lo3, d2h1lp3, d2h1lq3, d2h1lr3, d2h1ls3, d2h1lt3, d2h1lu3, d2h1lv3, d2h1lw3, d2h1lx3
        automated match to d3kmda_
        complexed with zn
      12. 2034339Domain d2h1lx2: 2h1l X:92-289 [135970]
        Other proteins in same PDB: d2h1la_, d2h1lb_, d2h1lc_, d2h1ld_, d2h1le_, d2h1lf_, d2h1lg_, d2h1lh_, d2h1li_, d2h1lj_, d2h1lk_, d2h1ll_, d2h1lm3, d2h1ln3, d2h1lo3, d2h1lp3, d2h1lq3, d2h1lr3, d2h1ls3, d2h1lt3, d2h1lu3, d2h1lv3, d2h1lw3, d2h1lx3
        automated match to d3kmda_
        complexed with zn
    9. Domain for 2mej:
    10. Domain for 2pcx:
    11. Domain for 2qvq:
    12. Domains for 2qxa:
      1. 2034258Domain d2qxaa_: 2qxa A: [304439]
        automated match to d4kvpc_
        complexed with zn; mutant
      2. 2034259Domain d2qxab_: 2qxa B: [304440]
        automated match to d4kvpc_
        complexed with zn; mutant
      3. 2034260Domain d2qxac_: 2qxa C: [304441]
        automated match to d4kvpc_
        complexed with zn; mutant
      4. 2034261Domain d2qxad_: 2qxa D: [304442]
        automated match to d4kvpc_
        complexed with zn; mutant
    13. Domains for 2qxb:
      1. 2034316Domain d2qxba_: 2qxb A: [304443]
        automated match to d2ac0a_
        complexed with zn; mutant
      2. 2034317Domain d2qxbb_: 2qxb B: [304444]
        automated match to d2ac0a_
        complexed with zn; mutant
      3. 2034318Domain d2qxbc_: 2qxb C: [304445]
        automated match to d2ac0a_
        complexed with zn; mutant
      4. 2034319Domain d2qxbd_: 2qxb D: [304446]
        automated match to d2ac0a_
        complexed with zn; mutant
    14. Domains for 2qxc:
      1. 2034297Domain d2qxca_: 2qxc A: [304447]
        automated match to d3igla_
        complexed with zn; mutant
      2. 2034298Domain d2qxcb_: 2qxc B: [304448]
        automated match to d3igla_
        complexed with zn; mutant
      3. 2034299Domain d2qxcc_: 2qxc C: [304449]
        automated match to d3igla_
        complexed with zn; mutant
      4. 2034300Domain d2qxcd_: 2qxc D: [304450]
        automated match to d3igla_
        complexed with zn; mutant
    15. Domain for 3d05:
    16. Domain for 3d06:
    17. Domains for 3d07:
      1. 2034295Domain d3d07a_: 3d07 A: [173590]
        automated match to d1gzha_
        complexed with zn; mutant
      2. 2034296Domain d3d07b_: 3d07 B: [173591]
        automated match to d1gzha_
        complexed with zn; mutant
    18. Domain for 3d08:
    19. Domain for 3d09:
    20. Domains for 3d0a:
      1. 2034264Domain d3d0aa_: 3d0a A: [173594]
        automated match to d1gzha_
        protein/DNA complex; protein/RNA complex; complexed with zn; mutant
      2. 2034265Domain d3d0ab_: 3d0a B: [173595]
        automated match to d1gzha_
        protein/DNA complex; protein/RNA complex; complexed with zn; mutant
      3. 2034266Domain d3d0ac_: 3d0a C: [173596]
        automated match to d1gzha_
        protein/DNA complex; protein/RNA complex; complexed with zn; mutant
      4. 2034267Domain d3d0ad_: 3d0a D: [173597]
        automated match to d1gzha_
        protein/DNA complex; protein/RNA complex; complexed with zn; mutant
    21. Domain for 3igk:
      • 2034253Domain d3igka_: 3igk A: [178310]
        automated match to d1gzha_
        protein/DNA complex; protein/RNA complex; complexed with zn
    22. Domain for 3igl:
      • 2034262Domain d3igla_: 3igl A: [178311]
        automated match to d1gzha_
        protein/DNA complex; protein/RNA complex; complexed with edo, zn
    23. Domains for 3kz8:
      1. 2034288Domain d3kz8a_: 3kz8 A: [179824]
        automated match to d1gzha_
        protein/DNA complex; complexed with iod, zn
      2. 2034289Domain d3kz8b_: 3kz8 B: [179825]
        automated match to d1gzha_
        protein/DNA complex; complexed with iod, zn
    24. Domains for 4ibq:
      1. 2034278Domain d4ibqa_: 4ibq A: [223098]
        automated match to d2ahia_
        complexed with act, edo, zn; mutant
      2. 2034279Domain d4ibqb_: 4ibq B: [223099]
        automated match to d2ahia_
        complexed with act, edo, zn; mutant
      3. 2034280Domain d4ibqc_: 4ibq C: [223100]
        automated match to d2ahia_
        complexed with act, edo, zn; mutant
      4. 2034281Domain d4ibqd_: 4ibq D: [223101]
        automated match to d2ahia_
        complexed with act, edo, zn; mutant
    25. Domains for 4ibs:
      1. 2034284Domain d4ibsa_: 4ibs A: [223102]
        automated match to d2ahia_
        complexed with edo, zn; mutant
      2. 2034285Domain d4ibsb_: 4ibs B: [223103]
        automated match to d2ahia_
        complexed with edo, zn; mutant
      3. 2034286Domain d4ibsc_: 4ibs C: [223104]
        automated match to d2ahia_
        complexed with edo, zn; mutant
      4. 2034287Domain d4ibsd_: 4ibs D: [223105]
        automated match to d2ahia_
        complexed with edo, zn; mutant
    26. Domains for 4ibt:
      1. 2034274Domain d4ibta_: 4ibt A: [223106]
        automated match to d2ahia_
        complexed with zn; mutant
      2. 2034275Domain d4ibtb_: 4ibt B: [223107]
        automated match to d2ahia_
        complexed with zn; mutant
      3. 2034276Domain d4ibtc_: 4ibt C: [223108]
        automated match to d2ahia_
        complexed with zn; mutant
      4. 2034277Domain d4ibtd_: 4ibt D: [223109]
        automated match to d2ahia_
        complexed with zn; mutant
    27. Domains for 4ibu:
      1. 2034268Domain d4ibua_: 4ibu A: [223110]
        automated match to d2ahia_
        protein/DNA complex; complexed with act, edo, zn; mutant
      2. 2034269Domain d4ibub_: 4ibu B: [223111]
        automated match to d2ahia_
        protein/DNA complex; complexed with act, edo, zn; mutant
      3. 2034270Domain d4ibuc_: 4ibu C: [223112]
        automated match to d2ahia_
        protein/DNA complex; complexed with act, edo, zn; mutant
      4. 2034271Domain d4ibud_: 4ibu D: [223113]
        automated match to d2ahia_
        protein/DNA complex; complexed with act, edo, zn; mutant
    28. Domain for 4ibv:
    29. Domain for 4ibw:
    30. Domains for 4iby:
      1. 2034251Domain d4ibya_: 4iby A: [223116]
        automated match to d2ahia_
        complexed with edo, zn; mutant
      2. 2034252Domain d4ibyb_: 4iby B: [223117]
        automated match to d2ahia_
        complexed with edo, zn; mutant
    31. Domains for 4ibz:
      1. 2034302Domain d4ibza_: 4ibz A: [223118]
        automated match to d2ahia_
        complexed with act, edo, zn; mutant
      2. 2034303Domain d4ibzb_: 4ibz B: [223119]
        automated match to d2ahia_
        complexed with act, edo, zn; mutant
      3. 2034304Domain d4ibzc_: 4ibz C: [223120]
        automated match to d2ahia_
        complexed with act, edo, zn; mutant
      4. 2034305Domain d4ibzd_: 4ibz D: [223121]
        automated match to d2ahia_
        complexed with act, edo, zn; mutant
    32. Domain for 4ijt:
    33. Domains for 4kvp:
      1. 2034254Domain d4kvpa_: 4kvp A: [224494]
        complexed with zn; mutant
      2. 2034255Domain d4kvpb_: 4kvp B: [224495]
        complexed with zn; mutant
      3. 2034256Domain d4kvpc_: 4kvp C: [224496]
        complexed with zn; mutant
      4. 2034257Domain d4kvpd_: 4kvp D: [224497]
        complexed with zn; mutant
    34. Domains for 4lo9:
      1. 2034322Domain d4lo9a_: 4lo9 A: [224722]
        complexed with zn; mutant
      2. 2034323Domain d4lo9b_: 4lo9 B: [224723]
        complexed with zn; mutant
      3. 2034324Domain d4lo9c_: 4lo9 C: [224724]
        complexed with zn; mutant
      4. 2034325Domain d4lo9d_: 4lo9 D: [224725]
        complexed with zn; mutant
    35. Domains for 4loe:
      1. 2034291Domain d4loea_: 4loe A: [224726]
        complexed with zn; mutant
      2. 2034292Domain d4loeb_: 4loe B: [224727]
        complexed with zn; mutant
      3. 2034293Domain d4loec_: 4loe C: [224728]
        complexed with zn; mutant
      4. 2034294Domain d4loed_: 4loe D: [224729]
        complexed with zn; mutant
    36. Domain for 4lof:
    37. Domain for 4mzi:
    38. Domain for 4qo1:
    39. Domains for 4xr8:
      1. 2268423Domain d4xr8d_: 4xr8 D: [311729]
        automated match to d1ycsa_
        complexed with edo, mal, peg, zn
      2. 2268543Domain d4xr8c_: 4xr8 C: [311849]
        automated match to d1ycsa_
        complexed with edo, mal, peg, zn
    40. Domains for 5lap:
      1. 2277830Domain d5lapb_: 5lap B: [321131]
        automated match to d2feja_
        complexed with 6sm, zn; mutant
      2. 2277839Domain d5lapa_: 5lap A: [321140]
        automated match to d2feja_
        complexed with 6sm, zn; mutant
  2. 2034342Mouse (Mus musculus) [TaxId:10090] [63683] (1 PDB entry)

More info for Protein p53 tumor suppressor, DNA-binding domain from b.2.5.2: p53 DNA-binding domain-like

Timeline for Protein p53 tumor suppressor, DNA-binding domain from b.2.5.2: p53 DNA-binding domain-like: