SCOPe 2.03: Domain d1gzhb1: 1gzh B:1724-1866

Lineage for d1gzhb1 (1gzh B:1724-1866)

1. Root: SCOPe 2.03

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.15: BRCT domain [52112] (1 superfamily)
   3 layers, a/b/a; core: parallel beta-sheet of 4 strands, order 2134

4. Superfamily c.15.1: BRCT domain [52113] (5 families)
   Pfam PF00533

5. Family c.15.1.4: 53BP1 [75148] (1 protein)

6. Protein 53BP1 [75149] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [75150] (2 PDB entries)

8. Domain d1gzhb1: 1gzh B:1724-1866 [70808]
   Other proteins in same PDB: d1gzha_, d1gzhc_
   complexed with so4, zn

Details for d1gzhb1

PDB Entry: 1gzh, 2.6 Å

PDB Description: Crystal structure of the BRCT domains of human 53BP1 bound to the p53 tumor supressor

PDB Compounds: (B:) tumor suppressor p53-binding protein 1

SCOPe Domain Sequences for d1gzhb1:

Sequence, based on SEQRES records:

>d1gzhb1 c.15.1.4 (B:1724-1866) 53BP1 {Human (Homo sapiens) [TaxId: 9606]}
lnktlflgyaflltmattsdklasrsklpdgptgsseeeeefleippfnkqytesqlrag
agyiledfneaqcntayqclliadqhcrtrkyflclasgipcvshvwvhdschanqlqny
rnyllpagysleeqrildwqpre

Sequence, based on observed residues (ATOM records):

>d1gzhb1 c.15.1.4 (B:1724-1866) 53BP1 {Human (Homo sapiens) [TaxId: 9606]}
lnktlflgyaflltmattsdklasrsppfnkqytesqlragagyiledfntayqclliad
qhcrtrkyflclasgipcvshvwvhdschanqlqnyrnyllpagysleeqrildwqpre

Timeline for d1gzhb1:

• d1gzhb1 first appeared in SCOP 1.61
  
• d1gzhb1 appears in SCOPe 2.02
  
• d1gzhb1 appears in SCOPe 2.04
  
• d1gzhb1 appears in the current release, SCOPe 2.08