SCOPe 2.03: Domain d4mzia_: 4mzi A:

Lineage for d4mzia_ (4mzi A:)

1. Root: SCOPe 2.03

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.2: Common fold of diphtheria toxin/transcription factors/cytochrome f [49379] (10 superfamilies)
   sandwich; 9 strands in 2 sheet; greek-key; subclass of immunoglobin-like fold

4. Superfamily b.2.5: p53-like transcription factors [49417] (7 families)

5. Family b.2.5.2: p53 DNA-binding domain-like [81314] (3 proteins)

6. Protein p53 tumor suppressor, DNA-binding domain [49419] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [49420] (32 PDB entries)

8. Domain d4mzia_: 4mzi A: [236070]
   automated match to d3igla_
   complexed with zn; mutant

Details for d4mzia_

PDB Entry: 4mzi, 1.25 Å

PDB Description: crystal structure of a human mutant p53

PDB Compounds: (A:) Cellular tumor antigen p53

SCOPe Domain Sequences for d4mzia_:

Sequence; same for both SEQRES and ATOM records:

>d4mzia_ b.2.5.2 (A:) p53 tumor suppressor, DNA-binding domain {Human (Homo sapiens) [TaxId: 9606]}
svpsqktyqgsygfrlgflhsgtakfgtctyspalnkmfvqlaktvpvqlyvdstpppgt
rvramaiykqsqhmtevvrrcphherssdsdglappqhlirvegnlraeylddpntfrhs
vvvpyeppevgsdyttiyfkfmcnsscmggmnrrpilviitledssgnllgrdsfevrvc
acpgrdrrteeen

Timeline for d4mzia_:

• d4mzia_ is new in SCOPe 2.03-stable
  
• d4mzia_ appears in SCOPe 2.04
  
• d4mzia_ appears in the current release, SCOPe 2.08