Class d: Alpha and beta proteins (a+b) [53931] (396 folds) |
Fold d.117: Thymidylate synthase/dCMP hydroxymethylase [55830] (1 superfamily) contains large mixed beta-sheet |
Superfamily d.117.1: Thymidylate synthase/dCMP hydroxymethylase [55831] (2 families) automatically mapped to Pfam PF00303 |
Family d.117.1.1: Thymidylate synthase/dCMP hydroxymethylase [55832] (4 proteins) |
Protein Thymidylate synthase [55833] (7 species) |
Species Escherichia coli [TaxId:562] [55834] (70 PDB entries) |
Domain d1aiqa_: 1aiq A: [40967] complexed with cb3, ump; mutant |
Domain d1aiqb_: 1aiq B: [40968] complexed with cb3, ump; mutant |
Domain d1ajma_: 1ajm A: [40981] mutant |
Domain d1an5a_: 1an5 A: [40986] complexed with cb3, po4 |
Domain d1an5b_: 1an5 B: [40987] complexed with cb3, po4 |
Domain d1aoba_: 1aob A: [40969] complexed with ddu, fmt, po4 |
Domain d1axwa_: 1axw A: [40938] complexed with mtx, ump |
Domain d1axwb_: 1axw B: [40939] complexed with mtx, ump |
Domain d1bdua_: 1bdu A: [40955] complexed with dur, po4 |
Domain d1bida_: 1bid A: [40960] complexed with ump |
Domain d1bjga_: 1bjg A: [40977] complexed with tmf, ufp; mutant |
Domain d1bq1a_: 1bq1 A: [40965] complexed with cb3, ump; mutant |
Domain d1bq1b_: 1bq1 B: [40966] complexed with cb3, ump; mutant |
Domain d1bq2a_: 1bq2 A: [40971] complexed with po4; mutant |
Domain d1ddua_: 1ddu A: [40961] complexed with cb3, ddu, po4 |
Domain d1ddub_: 1ddu B: [40962] complexed with cb3, ddu, po4 |
Domain d1dnaa_: 1dna A: [40956] complexed with cb3, ump; mutant |
Domain d1dnab_: 1dna B: [40957] complexed with cb3, ump; mutant |
Domain d1ev5a_: 1ev5 A: [40935] complexed with so4; mutant |
Domain d1ev8a_: 1ev8 A: [40989] mutant |
Domain d1evfa_: 1evf A: [40932] complexed with so4; mutant |
Domain d1evga_: 1evg A: [40954] complexed with so4; mutant |
Domain d1f4ba_: 1f4b A: [40936] complexed with gol, so4 |
Domain d1f4ca_: 1f4c A: [40950] complexed with gol, so4, tp2 |
Domain d1f4cb_: 1f4c B: [40951] complexed with gol, so4, tp2 |
Domain d1f4da_: 1f4d A: [40972] complexed with gol, so4, tp2 |
Domain d1f4db_: 1f4d B: [40973] complexed with gol, so4, tp2 |
Domain d1f4ea_: 1f4e A: [40941] complexed with gol, so4, tpr |
Domain d1f4fa_: 1f4f A: [40946] complexed with so4, tp3 |
Domain d1f4fb_: 1f4f B: [40947] complexed with so4, tp3 |
Domain d1f4ga_: 1f4g A: [40933] complexed with gol, so4, tp4 |
Domain d1f4gb_: 1f4g B: [40934] complexed with gol, so4, tp4 |
Domain d1ffla_: 1ffl A: [40988] mutant |
Domain d1fwma_: 1fwm A: [90500] complexed with cb3, so4; mutant |
Domain d1fwmb_: 1fwm B: [90501] complexed with cb3, so4; mutant |
Domain d1jg0a_: 1jg0 A: [66659] complexed with ddt, ump |
Domain d1jg0b_: 1jg0 B: [66660] complexed with ddt, ump |
Domain d1jtqa_: 1jtq A: [63282] complexed with ly3, ump |
Domain d1jtqb_: 1jtq B: [63283] complexed with ly3, ump |
Domain d1jtua_: 1jtu A: [63284] complexed with lyb, ump |
Domain d1jtub_: 1jtu B: [63285] complexed with lyb, ump |
Domain d1juta_: 1jut A: [63301] complexed with lyd, ump |
Domain d1jutb_: 1jut B: [63302] complexed with lyd, ump |
Domain d1kcea1: 1kce A:2-264 [40944] Other proteins in same PDB: d1kcea2, d1kceb2 complexed with cb3, ump; mutant |
Domain d1kceb1: 1kce B:2-264 [40945] Other proteins in same PDB: d1kcea2, d1kceb2 complexed with cb3, ump; mutant |
Domain d1kzia_: 1kzi A: [73363] complexed with co3, dtt, dtu, gol, thg, ump |
Domain d1kzib_: 1kzi B: [73364] complexed with co3, dtt, dtu, gol, thg, ump |
Domain d1kzja_: 1kzj A: [73365] complexed with cb3, ump |
Domain d1kzjb_: 1kzj B: [73366] complexed with cb3, ump |
Domain d1kzjc_: 1kzj C: [73367] complexed with cb3, ump |
Domain d1kzjd_: 1kzj D: [73368] complexed with cb3, ump |
Domain d1kzje_: 1kzj E: [73369] complexed with cb3, ump |
Domain d1kzjf_: 1kzj F: [73370] complexed with cb3, ump |
Domain d1ncea_: 1nce A: [80401] complexed with cb3, ump |
Domain d1nceb_: 1nce B: [80402] complexed with cb3, ump |
Domain d1qqqa_: 1qqq A: [40931] complexed with so4; mutant |
Domain d1syna_: 1syn A: [40958] complexed with f89, ump |
Domain d1synb_: 1syn B: [40959] complexed with f89, ump |
Domain d1tdua_: 1tdu A: [40963] complexed with cb3, dur, po4 |
Domain d1tdub_: 1tdu B: [40964] complexed with cb3, dur, po4 |
Domain d1tjsa_: 1tjs A: [40976] complexed with po4 |
Domain d1tlca_: 1tlc A: [40942] complexed with dgp, f89 |
Domain d1tlcb_: 1tlc B: [40943] complexed with dgp, f89 |
Domain d1tlsa1: 1tls A:2-264 [40982] Other proteins in same PDB: d1tlsa2, d1tlsb2 complexed with c2f, ufp |
Domain d1tlsb1: 1tls B:2-264 [40983] Other proteins in same PDB: d1tlsa2, d1tlsb2 complexed with c2f, ufp |
Domain d1trga_: 1trg A: [40940] complexed with cb3, ump |
Domain d1tsda_: 1tsd A: [40948] complexed with bme, f89, ump |
Domain d1tsdb_: 1tsd B: [40949] complexed with bme, f89, ump |
Domain d1tsna1: 1tsn A:2-264 [40970] Other proteins in same PDB: d1tsna2 complexed with c2f, po4, ufp |
Domain d1tysa_: 1tys A: [40937] complexed with dhf, tmp |
Domain d1zpra_: 1zpr A: [40978] complexed with cb3, ump; mutant |
Domain d1zprb_: 1zpr B: [40979] complexed with cb3, ump; mutant |
Domain d2a9wa_: 2a9w A: [126456] automated match to d1an5a_ complexed with 2br, bme, ga9, gol, po4, ump |
Domain d2a9wb_: 2a9w B: [126457] automated match to d1an5a_ complexed with 2br, bme, ga9, gol, po4, ump |
Domain d2a9wc_: 2a9w C: [126458] automated match to d1an5a_ complexed with 2br, bme, ga9, gol, po4, ump |
Domain d2a9wd_: 2a9w D: [126459] automated match to d1an5a_ complexed with 2br, bme, ga9, gol, po4, ump |
Domain d2bbqa_: 2bbq A: [40974] complexed with pfg, ump |
Domain d2bbqb_: 2bbq B: [40975] complexed with pfg, ump |
Domain d2ftna_: 2ftn A: [164466] automated match to d1an5a_ complexed with so4; mutant |
Domain d2ftox_: 2fto X: [164467] automated match to d1an5a_ complexed with cb3, po4, tmp; mutant |
Domain d2ftqa_: 2ftq A: [134076] automated match to d1an5a_ complexed with po4, so4 |
Domain d2g8ma_: 2g8m A: [303922] automated match to d4geva_ complexed with cb3, ump |
Domain d2g8mb_: 2g8m B: [303923] automated match to d4geva_ complexed with cb3, ump |
Domain d2g8oa_: 2g8o A: [303924] automated match to d1f4ba_ complexed with cb3, ump |
Domain d2g8ob_: 2g8o B: [303925] automated match to d1f4ba_ complexed with cb3, ump |
Domain d2g8xa_: 2g8x A: [164605] automated match to d1an5a_ complexed with co3, dtt, po4 |
Domain d2g8xb_: 2g8x B: [164606] automated match to d1an5a_ complexed with co3, dtt, po4 |
Domain d2kcea_: 2kce A: [40984] complexed with d16, ump |
Domain d2kceb_: 2kce B: [40985] complexed with d16, ump |
Domain d2tsca_: 2tsc A: [40952] complexed with cb3, ump |
Domain d2tscb_: 2tsc B: [40953] complexed with cb3, ump |
Domain d2veta_: 2vet A: [168497] automated match to d1aiqa_ protein/RNA complex; complexed with fmt, ump |
Domain d2vf0a_: 2vf0 A: [243863] automated match to d2veta_ protein/RNA complex; complexed with f89, ndu, so4 |
Domain d2vf0b_: 2vf0 B: [243864] automated match to d2veta_ protein/RNA complex; complexed with f89, ndu, so4 |
Domain d3b5ba_: 3b5b A: [172428] automated match to d1aiqa_ complexed with fmt, ndn, ndu |
Domain d3b5bb_: 3b5b B: [172429] automated match to d1aiqa_ complexed with fmt, ndn, ndu |
Domain d3b9ha_: 3b9h A: [172508] automated match to d1aiqa_ protein/RNA complex; complexed with ndu, po4 |
Domain d3bfia_: 3bfi A: [172592] automated match to d1an5a_ protein/RNA complex; complexed with ndu, so4; mutant |
Domain d3bgxa_: 3bgx A: [172629] automated match to d1an5a_ protein/RNA complex; complexed with mef, so4, tmp; mutant |
Domain d3bhla_: 3bhl A: [172637] automated match to d1aiqa_ protein/RNA complex; complexed with ndu, so4, thg |
Domain d3bhlb_: 3bhl B: [172638] automated match to d1aiqa_ protein/RNA complex; complexed with ndu, so4, thg |
Domain d3bhra_: 3bhr A: [172642] automated match to d1aiqa_ protein/RNA complex; complexed with ndu, po4, thg |
Domain d3tmsa_: 3tms A: [40980] complexed with po4; mutant |
Domain d4geva_: 4gev A: [192445] automated match to d2g8ma_ complexed with cb3, umc |
Domain d4gevb_: 4gev B: [192446] automated match to d2g8ma_ complexed with cb3, umc |
Domain d4iska1: 4isk A:2-264 [230059] Other proteins in same PDB: d4iska2, d4iskb2, d4iskc2, d4iskd2, d4iske2, d4iskf2, d4iskg2, d4iskh2 automated match to d1f4ba_ complexed with 1jy, mg, umc, ump |
Domain d4iskb1: 4isk B:2-264 [230056] Other proteins in same PDB: d4iska2, d4iskb2, d4iskc2, d4iskd2, d4iske2, d4iskf2, d4iskg2, d4iskh2 automated match to d1f4ba_ complexed with 1jy, mg, umc, ump |
Domain d4iskc1: 4isk C:2-264 [230058] Other proteins in same PDB: d4iska2, d4iskb2, d4iskc2, d4iskd2, d4iske2, d4iskf2, d4iskg2, d4iskh2 automated match to d1f4ba_ complexed with 1jy, mg, umc, ump |
Domain d4iskd1: 4isk D:2-264 [230057] Other proteins in same PDB: d4iska2, d4iskb2, d4iskc2, d4iskd2, d4iske2, d4iskf2, d4iskg2, d4iskh2 automated match to d1f4ba_ complexed with 1jy, mg, umc, ump |
Domain d4iske1: 4isk E:2-264 [230060] Other proteins in same PDB: d4iska2, d4iskb2, d4iskc2, d4iskd2, d4iske2, d4iskf2, d4iskg2, d4iskh2 automated match to d1f4ba_ complexed with 1jy, mg, umc, ump |
Domain d4iskf1: 4isk F:2-264 [230063] Other proteins in same PDB: d4iska2, d4iskb2, d4iskc2, d4iskd2, d4iske2, d4iskf2, d4iskg2, d4iskh2 automated match to d1f4ba_ complexed with 1jy, mg, umc, ump |
Domain d4iskg1: 4isk G:2-264 [230061] Other proteins in same PDB: d4iska2, d4iskb2, d4iskc2, d4iskd2, d4iske2, d4iskf2, d4iskg2, d4iskh2 automated match to d1f4ba_ complexed with 1jy, mg, umc, ump |
Domain d4iskh1: 4isk H:2-264 [230062] Other proteins in same PDB: d4iska2, d4iskb2, d4iskc2, d4iskd2, d4iske2, d4iskf2, d4iskg2, d4iskh2 automated match to d1f4ba_ complexed with 1jy, mg, umc, ump |
Domain d4iw5a_: 4iw5 A: [307561] automated match to d1f4ba_ complexed with cb3, mg, umc |
Domain d4iw5b_: 4iw5 B: [307562] automated match to d1f4ba_ complexed with cb3, mg, umc |
Domain d4lrra_: 4lrr A: [228800] automated match to d1f4ba_ complexed with cf9, so4, ump |
Domain d6cdza_: 6cdz A: [352049] automated match to d4iw5a_ complexed with cb3, umc, ump; mutant |
Domain d6cdzb_: 6cdz B: [352051] automated match to d4iw5a_ complexed with cb3, umc, ump; mutant |
Domain d6nnra_: 6nnr A: [364276] automated match to d1kzia_ complexed with cb3, epe, na, umc |
Domain d6nnrb_: 6nnr B: [364279] automated match to d1kzia_ complexed with cb3, epe, na, umc |
Domain d7jx1a_: 7jx1 A: [403371] automated match to d1kzia_ complexed with po4, tmp, vla, vld |
Domain d7jx1b_: 7jx1 B: [403326] automated match to d1kzia_ complexed with po4, tmp, vla, vld |
Domain d7jxfa_: 7jxf A: [403404] automated match to d1kzia_ complexed with 5hu, na, vmv, vnm |
Domain d7jxfb_: 7jxf B: [403481] automated match to d1kzia_ complexed with 5hu, na, vmv, vnm |
Timeline for Species Escherichia coli [TaxId:562] from d.117.1.1 Thymidylate synthase: