SCOPe 2.08: Domain d2g8oa_: 2g8o A:

Lineage for d2g8oa_ (2g8o A:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.117: Thymidylate synthase/dCMP hydroxymethylase [55830] (1 superfamily)
   contains large mixed beta-sheet

4. Superfamily d.117.1: Thymidylate synthase/dCMP hydroxymethylase [55831] (2 families)
   automatically mapped to Pfam PF00303

5. Family d.117.1.1: Thymidylate synthase/dCMP hydroxymethylase [55832] (4 proteins)

6. Protein Thymidylate synthase [55833] (7 species)

7. Species Escherichia coli [TaxId:562] [55834] (70 PDB entries)

8. Domain d2g8oa_: 2g8o A: [303924]
   automated match to d1f4ba_
   complexed with cb3, ump

Details for d2g8oa_

PDB Entry: 2g8o, 1.3 Å

PDB Description: High resolution structure of Escherichia coli thymidylate synthase ternary complex with dUMP and a cofactor analog, CB3717

PDB Compounds: (A:) Thymidylate synthase

SCOPe Domain Sequences for d2g8oa_:

Sequence; same for both SEQRES and ATOM records:

>d2g8oa_ d.117.1.1 (A:) Thymidylate synthase {Escherichia coli [TaxId: 562]}
mkqylelmqkvldegtqkndrtgtgtlsifghqmrfnlqdgfplvttkrchlrsiihell
wflqgdtniaylhennvtiwdewadengdlgpvygkqwrawptpdgrhidqittvlnqlk
ndpdsrriivsawnvgeldkmalapchaffqfyvadgklscqlyqrscdvflglpfnias
yallvhmmaqqcdlevgdfvwtggdthlysnhmdqthlqlsreprplpkliikrkpesif
dyrfedfeiegydphpgikapvai

Timeline for d2g8oa_:

• d2g8oa_ first appeared in SCOPe 2.06
  
• d2g8oa_ appears in SCOPe 2.07