SCOPe 2.08: Domain d1nceb_: 1nce B:

Lineage for d1nceb_ (1nce B:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.117: Thymidylate synthase/dCMP hydroxymethylase [55830] (1 superfamily)
   contains large mixed beta-sheet

4. Superfamily d.117.1: Thymidylate synthase/dCMP hydroxymethylase [55831] (2 families)
   automatically mapped to Pfam PF00303

5. Family d.117.1.1: Thymidylate synthase/dCMP hydroxymethylase [55832] (4 proteins)

6. Protein Thymidylate synthase [55833] (7 species)

7. Species Escherichia coli [TaxId:562] [55834] (70 PDB entries)

8. Domain d1nceb_: 1nce B: [80402]
   complexed with cb3, ump

Details for d1nceb_

PDB Entry: 1nce, 2.4 Å

PDB Description: crystal structure of a ternary complex of e. coli thymidylate synthase d169c with dump and the antifolate cb3717

PDB Compounds: (B:) Thymidylate synthase

SCOPe Domain Sequences for d1nceb_:

Sequence; same for both SEQRES and ATOM records:

>d1nceb_ d.117.1.1 (B:) Thymidylate synthase {Escherichia coli [TaxId: 562]}
mkqylelmqkvldegtqkndrtgtgtlsifghqmrfnlqdgfplvttkrchlrsiihell
wflqgdtniaylhennvtiwdewadengdlgpvygkqwrawptpdgrhidqittvlnqlk
ndpdsrriivsawnvgeldkmalapchaffqfyvadgklscqlyqrsccvflglpfnias
yallvhmmaqqcdlevgdfvwtggdthlysnhmdqthlqlsreprplpkliikrkpesif
dyrfedfeiegydphpgikapvai

Timeline for d1nceb_:

• d1nceb_ first appeared in SCOP 1.63
  
• d1nceb_ appears in SCOPe 2.07