PDB entry 3b5b

View 3b5b on RCSB PDB site
Description: Crystal structure of the thymidylate synthase k48q
Class: transferase
Keywords: Thymidylate synthase, 5-NO2-DUMP, Substrate Anologue, Methyltransferase, Nucleotide biosynthesis, Repressor, RNA-binding, Transferase, Translation regulation
Deposited on 2007-10-25, released 2007-12-25
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-07-24, with a file datestamp of 2019-07-19.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: N/A
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Thymidylate synthase
    Species: ESCHERICHIA COLI [TaxId:511693]
    Gene: thyA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A884 (0-263)
      • engineered (47)
    Domains in SCOPe 2.08: d3b5ba_
  • Chain 'B':
    Compound: Thymidylate synthase
    Species: ESCHERICHIA COLI [TaxId:511693]
    Gene: thyA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A884 (0-263)
      • engineered (47)
    Domains in SCOPe 2.08: d3b5bb_
  • Heterogens: NDU, FMT, NDN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3b5bA (A:)
mkqylelmqkvldegtqkndrtgtgtlsifghqmrfnlqdgfplvttqrchlrsiihell
wflqgdtniaylhennvtiwdewadengdlgpvygkqwrawptpdgrhidqittvlnqlk
ndpdsrriivsawnvgeldkmalapchaffqfyvadgklscqlyqrscdvflglpfnias
yallvhmmaqqcdlevgdfvwtggdthlysnhmdqthlqlsreprplpkliikrkpesif
dyrfedfeiegydphpgikapvai

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3b5bB (B:)
mkqylelmqkvldegtqkndrtgtgtlsifghqmrfnlqdgfplvttqrchlrsiihell
wflqgdtniaylhennvtiwdewadengdlgpvygkqwrawptpdgrhidqittvlnqlk
ndpdsrriivsawnvgeldkmalapchaffqfyvadgklscqlyqrscdvflglpfnias
yallvhmmaqqcdlevgdfvwtggdthlysnhmdqthlqlsreprplpkliikrkpesif
dyrfedfeiegydphpgikapvai