Lineage for Protein: Flap endonuclease-1 (Fen-1 nuclease)

  1. Root: SCOPe 2.07
  2. 2413226Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2492881Fold c.120: PIN domain-like [88722] (1 superfamily)
    3 layers, a/b/a; core: parallel beta-sheet of 5 strands, order 32145
  4. 2492882Superfamily c.120.1: PIN domain-like [88723] (3 families) (S)
  5. 2492943Family c.120.1.2: 5' to 3' exonuclease catalytic domain [53045] (4 protein domains)
    contains an alpha-helical arch and additional strand 6 antiparallel to the rest; strand order 321456; similarity to the resolvase-like fold
  6. 2492950Protein Flap endonuclease-1 (Fen-1 nuclease) [53052] (5 species)

Species:

  1. 2492951Archaeoglobus fulgidus [TaxId:2234] [102272] (2 PDB entries)
    1. Domains for 1rxv:
      1. 2492953Domain d1rxva2: 1rxv A:4-219 [98056]
        Other proteins in same PDB: d1rxva1, d1rxvb1
        protein/DNA complex
      2. 2492954Domain d1rxvb2: 1rxv B:4-219 [98058]
        Other proteins in same PDB: d1rxva1, d1rxvb1
        protein/DNA complex
    2. Domain for 1rxw:
  2. 2492955Human (Homo sapiens) [TaxId:9606] [142118] (1 PDB entry)
    Uniprot P39748 2-217
  3. 2492959Methanococcus jannaschii [TaxId:2190] [53053] (2 PDB entries)
    1. Domain for 1a76:
    2. Domain for 1a77:
  4. 2492962Pyrococcus furiosus [TaxId:2261] [53055] (1 PDB entry)
  5. 2492965Pyrococcus horikoshii [TaxId:53953] [82436] (1 PDB entry)

More info for Protein Flap endonuclease-1 (Fen-1 nuclease) from c.120.1.2: 5' to 3' exonuclease catalytic domain

Timeline for Protein Flap endonuclease-1 (Fen-1 nuclease) from c.120.1.2: 5' to 3' exonuclease catalytic domain: