Lineage for Family c.120.1.2: 5' to 3' exonuclease catalytic domain

  1. Root: SCOPe 2.07
  2. 2413226Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2492881Fold c.120: PIN domain-like [88722] (1 superfamily)
    3 layers, a/b/a; core: parallel beta-sheet of 5 strands, order 32145
  4. 2492882Superfamily c.120.1: PIN domain-like [88723] (3 families) (S)
  5. 2492943Family c.120.1.2: 5' to 3' exonuclease catalytic domain [53045] (4 protein domains)
    contains an alpha-helical arch and additional strand 6 antiparallel to the rest; strand order 321456; similarity to the resolvase-like fold

Protein Domains:

  1. 24929445' to 3' exonuclease domain of DNA polymerase Taq [53048] (1 species)
  2. 2492950Flap endonuclease-1 (Fen-1 nuclease) [53052] (5 species)
    1. 2492951Species Archaeoglobus fulgidus [TaxId:2234] [102272] (2 PDB entries)
    2. 2492955Species Human (Homo sapiens) [TaxId:9606] [142118] (1 PDB entry)
      Uniprot P39748 2-217
    3. 2492959Species Methanococcus jannaschii [TaxId:2190] [53053] (2 PDB entries)
    4. 2492962Species Pyrococcus furiosus [TaxId:2261] [53055] (1 PDB entry)
    5. 2492965Species Pyrococcus horikoshii [TaxId:53953] [82436] (1 PDB entry)
  3. 2492968T4 RNase H [53046] (1 species)
  4. 2492976T5 5'-exonuclease [53050] (1 species)

More info for Family c.120.1.2: 5' to 3' exonuclease catalytic domain

Timeline for Family c.120.1.2: 5' to 3' exonuclease catalytic domain: