SCOPe 2.08: Domain d1rxva2: 1rxv A:4-219

Lineage for d1rxva2 (1rxv A:4-219)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.120: PIN domain-like [88722] (1 superfamily)
   3 layers, a/b/a; core: parallel beta-sheet of 5 strands, order 32145

4. Superfamily c.120.1: PIN domain-like [88723] (4 families)

5. Family c.120.1.2: 5' to 3' exonuclease catalytic domain [53045] (4 proteins)
   contains an alpha-helical arch and additional strand 6 antiparallel to the rest; strand order 321456; similarity to the resolvase-like fold

6. Protein Flap endonuclease-1 (Fen-1 nuclease) [53052] (5 species)

7. Species Archaeoglobus fulgidus [TaxId:2234] [102272] (2 PDB entries)

8. Domain d1rxva2: 1rxv A:4-219 [98056]
   Other proteins in same PDB: d1rxva1, d1rxvb1
   protein/DNA complex
   missing some secondary structures that made up less than one-third of the common domain

Details for d1rxva2

PDB Entry: 1rxv, 2.5 Å

PDB Description: Crystal Structure of A. Fulgidus FEN-1 bound to DNA

PDB Compounds: (A:) Flap structure-specific endonuclease

SCOPe Domain Sequences for d1rxva2:

Sequence, based on SEQRES records:

>d1rxva2 c.120.1.2 (A:4-219) Flap endonuclease-1 (Fen-1 nuclease) {Archaeoglobus fulgidus [TaxId: 2234]}
digdlfereeveleyfsgkkiavdafntlyqfisiirqpdgtplkdsqgritshlsgily
rvsnmvevgirpvfvfdgeppefkkaeieerkkrraeaeemwiaalqagdkdakkyaqaa
grvdeyivdsaktllsymgipfvdapsegeaqaaymaakgdveytgsqdydsllfgsprl
arnlaitgkrklpgknvyvdvkpeiiilesnlkrlg

Sequence, based on observed residues (ATOM records):

>d1rxva2 c.120.1.2 (A:4-219) Flap endonuclease-1 (Fen-1 nuclease) {Archaeoglobus fulgidus [TaxId: 2234]}
digdlfereeveleyfsgkkiavdafntlyqfisiirqpdgtplkdsqgritshlsgily
rvsnmvevgirpvfvfdgeppefkkaeieerkkrraeaeemwiaalqagdkdakkyaqaa
grvdeyivdsaktllsymgipfvdapsegeaqaaymaakgdveytgsqdydsllfgsprl
arnlaikpeiiilesnlkrlg

Timeline for d1rxva2:

• d1rxva2 first appeared in SCOP 1.67
  
• d1rxva2 appears in SCOPe 2.07