Lineage for Protein: Tumor necrosis factor (TNF)

  1. Root: SCOPe 2.06
  2. 2021373Class b: All beta proteins [48724] (177 folds)
  3. 2048772Fold b.22: TNF-like [49841] (1 superfamily)
    sandwich, 10 strands in 2 sheets; jelly-roll
  4. 2048773Superfamily b.22.1: TNF-like [49842] (2 families) (S)
  5. 2048774Family b.22.1.1: TNF-like [49843] (15 proteins)
  6. 2048971Protein Tumor necrosis factor (TNF) [49848] (2 species)

Species:

  1. 2048972Human (Homo sapiens) [TaxId:9606] [49849] (19 PDB entries)
    1. Domains for 1a8m:
      1. 2049004Domain d1a8ma_: 1a8m A: [23868]
        mutant
      2. 2049005Domain d1a8mb_: 1a8m B: [23869]
        mutant
      3. 2049006Domain d1a8mc_: 1a8m C: [23870]
        mutant
    2. Domains for 1tnf:
      1. 2049019Domain d1tnfa_: 1tnf A: [23871]
      2. 2049020Domain d1tnfb_: 1tnf B: [23872]
      3. 2049021Domain d1tnfc_: 1tnf C: [23873]
    3. Domain for 1tnr:
    4. Domains for 2az5:
      1. 2048975Domain d2az5a_: 2az5 A: [127599]
        automated match to d1tnfa_
        complexed with 307
      2. 2048976Domain d2az5b_: 2az5 B: [127600]
        automated match to d1tnfa_
        complexed with 307
      3. 2048977Domain d2az5c_: 2az5 C: [127601]
        automated match to d1tnfa_
        complexed with 307
      4. 2048978Domain d2az5d_: 2az5 D: [127602]
        automated match to d1tnfa_
        complexed with 307
    5. Domains for 2tun:
      1. 2049025Domain d2tuna_: 2tun A: [23874]
        mutant
      2. 2049026Domain d2tunb_: 2tun B: [23875]
        mutant
      3. 2049027Domain d2tunc_: 2tun C: [23876]
        mutant
      4. 2049028Domain d2tund_: 2tun D: [23877]
        mutant
      5. 2049029Domain d2tune_: 2tun E: [23878]
        mutant
      6. 2049030Domain d2tunf_: 2tun F: [23879]
        mutant
    6. Domains for 2zjc:
      1. 2048983Domain d2zjca_: 2zjc A: [171243]
        automated match to d1a8ma_
        complexed with gol; mutant
      2. 2048984Domain d2zjcb_: 2zjc B: [171244]
        automated match to d1a8ma_
        complexed with gol; mutant
      3. 2048985Domain d2zjcc_: 2zjc C: [171245]
        automated match to d1a8ma_
        complexed with gol; mutant
    7. Domains for 2zpx:
      1. 2049022Domain d2zpxa_: 2zpx A: [171412]
        automated match to d1a8ma_
        mutant
      2. 2049023Domain d2zpxb_: 2zpx B: [171413]
        automated match to d1a8ma_
        mutant
      3. 2049024Domain d2zpxc_: 2zpx C: [171414]
        automated match to d1a8ma_
        mutant
    8. Domains for 3alq:
      1. 2049013Domain d3alqa_: 3alq A: [245160]
        automated match to d1a8ma_
        complexed with co
      2. 2049014Domain d3alqb_: 3alq B: [245161]
        automated match to d1a8ma_
        complexed with co
      3. 2049015Domain d3alqc_: 3alq C: [245162]
        automated match to d1a8ma_
        complexed with co
      4. 2049016Domain d3alqd_: 3alq D: [245163]
        automated match to d1a8ma_
        complexed with co
      5. 2049017Domain d3alqe_: 3alq E: [245164]
        automated match to d1a8ma_
        complexed with co
      6. 2049018Domain d3alqf_: 3alq F: [245165]
        automated match to d1a8ma_
        complexed with co
    9. Domain for 3l9j:
    10. Domain for 3wd5:
    11. Domain for 4g3y:
    12. Domain for 4tsv:
    13. Domains for 4tsw:
      1. 2048992Domain d4tswa_: 4tsw A: [309664]
        automated match to d5tswa_
        mutant
      2. 2048993Domain d4tswb_: 4tsw B: [309665]
        automated match to d5tswa_
        mutant
      3. 2048994Domain d4tswc_: 4tsw C: [309666]
        automated match to d5tswa_
        mutant
      4. 2048995Domain d4tswd_: 4tsw D: [309667]
        automated match to d5tswa_
        mutant
      5. 2048996Domain d4tswe_: 4tsw E: [309668]
        automated match to d5tswa_
        mutant
      6. 2048997Domain d4tswf_: 4tsw F: [309669]
        automated match to d5tswa_
        mutant
    14. Domains for 5m2i:
      1. 2048998Domain d5m2ia_: 5m2i A: [338539]
        Other proteins in same PDB: d5m2ig_, d5m2ih_, d5m2ii_, d5m2ij_, d5m2ik_, d5m2il_
        automated match to d1a8ma_
      2. 2048999Domain d5m2ib_: 5m2i B: [338554]
        Other proteins in same PDB: d5m2ig_, d5m2ih_, d5m2ii_, d5m2ij_, d5m2ik_, d5m2il_
        automated match to d1a8ma_
      3. 2049000Domain d5m2ic_: 5m2i C: [338538]
        Other proteins in same PDB: d5m2ig_, d5m2ih_, d5m2ii_, d5m2ij_, d5m2ik_, d5m2il_
        automated match to d1a8ma_
      4. 2049001Domain d5m2id_: 5m2i D: [338540]
        Other proteins in same PDB: d5m2ig_, d5m2ih_, d5m2ii_, d5m2ij_, d5m2ik_, d5m2il_
        automated match to d1a8ma_
      5. 2049002Domain d5m2ie_: 5m2i E: [338542]
        Other proteins in same PDB: d5m2ig_, d5m2ih_, d5m2ii_, d5m2ij_, d5m2ik_, d5m2il_
        automated match to d1a8ma_
      6. 2049003Domain d5m2if_: 5m2i F: [338541]
        Other proteins in same PDB: d5m2ig_, d5m2ih_, d5m2ii_, d5m2ij_, d5m2ik_, d5m2il_
        automated match to d1a8ma_
    15. Domain for 5m2j:
    16. Domains for 5m2m:
      1. 2049007Domain d5m2ma_: 5m2m A: [338556]
        Other proteins in same PDB: d5m2md_, d5m2me_, d5m2mf_, d5m2mh_, d5m2mj_, d5m2mn_
        automated match to d1a8ma_
      2. 2049008Domain d5m2mb_: 5m2m B: [338555]
        Other proteins in same PDB: d5m2md_, d5m2me_, d5m2mf_, d5m2mh_, d5m2mj_, d5m2mn_
        automated match to d1a8ma_
      3. 2049009Domain d5m2mc_: 5m2m C: [338525]
        Other proteins in same PDB: d5m2md_, d5m2me_, d5m2mf_, d5m2mh_, d5m2mj_, d5m2mn_
        automated match to d1a8ma_
      4. 2049010Domain d5m2mg_: 5m2m G: [338616]
        Other proteins in same PDB: d5m2md_, d5m2me_, d5m2mf_, d5m2mh_, d5m2mj_, d5m2mn_
        automated match to d1a8ma_
      5. 2049011Domain d5m2mi_: 5m2m I: [338533]
        Other proteins in same PDB: d5m2md_, d5m2me_, d5m2mf_, d5m2mh_, d5m2mj_, d5m2mn_
        automated match to d1a8ma_
      6. 2049012Domain d5m2mm_: 5m2m M: [338552]
        Other proteins in same PDB: d5m2md_, d5m2me_, d5m2mf_, d5m2mh_, d5m2mj_, d5m2mn_
        automated match to d1a8ma_
    17. Domains for 5mu8:
      1. 2049031Domain d5mu8a_: 5mu8 A: [332502]
        automated match to d1a8ma_
        complexed with jni
      2. 2049032Domain d5mu8b_: 5mu8 B: [332482]
        automated match to d1a8ma_
        complexed with jni
      3. 2049033Domain d5mu8c_: 5mu8 C: [332470]
        automated match to d1a8ma_
        complexed with jni
      4. 2049034Domain d5mu8d_: 5mu8 D: [332413]
        automated match to d1a8ma_
        complexed with jni
      5. 2049035Domain d5mu8e_: 5mu8 e: [332515]
        automated match to d1a8ma_
        complexed with jni
      6. 2049036Domain d5mu8f_: 5mu8 F: [332415]
        automated match to d1a8ma_
        complexed with jni
      7. 2049037Domain d5mu8g_: 5mu8 G: [332520]
        automated match to d1a8ma_
        complexed with jni
      8. 2049038Domain d5mu8h_: 5mu8 H: [332513]
        automated match to d1a8ma_
        complexed with jni
      9. 2049039Domain d5mu8i_: 5mu8 I: [332417]
        automated match to d1a8ma_
        complexed with jni
      10. 2049040Domain d5mu8j_: 5mu8 J: [332469]
        automated match to d1a8ma_
        complexed with jni
      11. 2049041Domain d5mu8k_: 5mu8 K: [332516]
        automated match to d1a8ma_
        complexed with jni
      12. 2049042Domain d5mu8l_: 5mu8 L: [332481]
        automated match to d1a8ma_
        complexed with jni
      13. 2049043Domain d5mu8m_: 5mu8 M: [332512]
        automated match to d1a8ma_
        complexed with jni
      14. 2049044Domain d5mu8n_: 5mu8 N: [332479]
        automated match to d1a8ma_
        complexed with jni
      15. 2049045Domain d5mu8o_: 5mu8 O: [332426]
        automated match to d1a8ma_
        complexed with jni
      16. 2049046Domain d5mu8p_: 5mu8 P: [332514]
        automated match to d1a8ma_
        complexed with jni
      17. 2049047Domain d5mu8q_: 5mu8 Q: [332486]
        automated match to d1a8ma_
        complexed with jni
      18. 2049048Domain d5mu8r_: 5mu8 R: [332425]
        automated match to d1a8ma_
        complexed with jni
      19. 2049049Domain d5mu8s_: 5mu8 S: [332414]
        automated match to d1a8ma_
        complexed with jni
      20. 2049050Domain d5mu8t_: 5mu8 T: [332519]
        automated match to d1a8ma_
        complexed with jni
      21. 2049051Domain d5mu8u_: 5mu8 U: [332476]
        automated match to d1a8ma_
        complexed with jni
      22. 2049052Domain d5mu8v_: 5mu8 V: [332418]
        automated match to d1a8ma_
        complexed with jni
      23. 2049053Domain d5mu8w_: 5mu8 W: [332451]
        automated match to d1a8ma_
        complexed with jni
      24. 2049054Domain d5mu8x_: 5mu8 X: [332521]
        automated match to d1a8ma_
        complexed with jni
      25. 2049055Domain d5mu8y_: 5mu8 Y: [332466]
        automated match to d1a8ma_
        complexed with jni
      26. 2049056Domain d5mu8z_: 5mu8 Z: [332420]
        automated match to d1a8ma_
        complexed with jni
    18. Domains for 5tsw:
      1. 2048986Domain d5tswa_: 5tsw A: [23861]
        mutant
      2. 2048987Domain d5tswb_: 5tsw B: [23862]
        mutant
      3. 2048988Domain d5tswc_: 5tsw C: [23863]
        mutant
      4. 2048989Domain d5tswd_: 5tsw D: [23864]
        mutant
      5. 2048990Domain d5tswe_: 5tsw E: [23865]
        mutant
      6. 2048991Domain d5tswf_: 5tsw F: [23866]
        mutant
    19. Domain for 5uui:
  2. 2049058Mouse (Mus musculus) [TaxId:10090] [49850] (1 PDB entry)

More info for Protein Tumor necrosis factor (TNF) from b.22.1.1: TNF-like

Timeline for Protein Tumor necrosis factor (TNF) from b.22.1.1: TNF-like: