Lineage for Protein: FK-506 binding protein (FKBP12), an immunophilin

  1. Root: SCOPe 2.06
  2. 2152203Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2165782Fold d.26: FKBP-like [54533] (3 superfamilies)
    core: beta(2)-alpha-beta(2); antiparallel beta-sheet
  4. 2165783Superfamily d.26.1: FKBP-like [54534] (4 families) (S)
  5. 2165784Family d.26.1.1: FKBP immunophilin/proline isomerase [54535] (17 protein domains)
  6. 2165795Protein FK-506 binding protein (FKBP12), an immunophilin [54536] (2 species)
    cis-trans prolyl-isomerase

Species:

  1. 2165796Cow (Bos taurus) [TaxId:9913] [54538] (2 PDB entries)
    1. Domain for 1fkk:
    2. Domain for 1fkl:
  2. 2165799Human (Homo sapiens) [TaxId:9606] [54537] (42 PDB entries)
    1. Domains for 1a7x:
      1. 2165839Domain d1a7xa_: 1a7x A: [38405]
        complexed with fka
      2. 2165840Domain d1a7xb_: 1a7x B: [38406]
        complexed with fka
    2. Domains for 1b6c:
      1. 2165846Domain d1b6ca_: 1b6c A: [38413]
        Other proteins in same PDB: d1b6cb_, d1b6cd_, d1b6cf_, d1b6ch_
        complexed with so4
      2. 2165847Domain d1b6cc_: 1b6c C: [38414]
        Other proteins in same PDB: d1b6cb_, d1b6cd_, d1b6cf_, d1b6ch_
        complexed with so4
      3. 2165848Domain d1b6ce_: 1b6c E: [38415]
        Other proteins in same PDB: d1b6cb_, d1b6cd_, d1b6cf_, d1b6ch_
        complexed with so4
      4. 2165849Domain d1b6cg_: 1b6c G: [38416]
        Other proteins in same PDB: d1b6cb_, d1b6cd_, d1b6cf_, d1b6ch_
        complexed with so4
    3. Domain for 1bkf:
    4. Domains for 1bl4:
      1. 2165822Domain d1bl4a_: 1bl4 A: [38393]
        complexed with ap1; mutant
      2. 2165823Domain d1bl4b_: 1bl4 B: [38394]
        complexed with ap1; mutant
    5. Domains for 1d6o:
      1. 2165817Domain d1d6oa_: 1d6o A: [38391]
        complexed with nh4, so4
      2. 2165818Domain d1d6ob_: 1d6o B: [38392]
        complexed with nh4, so4
    6. Domains for 1d7h:
      1. 2165827Domain d1d7ha_: 1d7h A: [38398]
        complexed with dms, nh4, so4
      2. 2165828Domain d1d7hb_: 1d7h B: [38399]
        complexed with dms, nh4, so4
    7. Domains for 1d7i:
      1. 2165825Domain d1d7ia_: 1d7i A: [38396]
        complexed with dss, nh4, so4
      2. 2165826Domain d1d7ib_: 1d7i B: [38397]
        complexed with dss, nh4, so4
    8. Domains for 1d7j:
      1. 2165813Domain d1d7ja_: 1d7j A: [38389]
        complexed with buq, nh4, so4
      2. 2165814Domain d1d7jb_: 1d7j B: [38390]
        complexed with buq, nh4, so4
    9. Domains for 1eym:
      1. 2165834Domain d1eyma_: 1eym A: [38403]
        mutant
      2. 2165835Domain d1eymb_: 1eym B: [38404]
        mutant
    10. Domain for 1f40:
    11. Domain for 1fap:
    12. Domain for 1fkb:
    13. Domain for 1fkd:
    14. Domain for 1fkf:
    15. Domain for 1fkg:
    16. Domain for 1fkh:
    17. Domains for 1fki:
      1. 2165832Domain d1fkia_: 1fki A: [38401]
        complexed with sb1
      2. 2165833Domain d1fkib_: 1fki B: [38402]
        complexed with sb1
    18. Domain for 1fkj:
    19. Domain for 1fkr:
    20. Domain for 1fks:
    21. Domain for 1fkt:
    22. Domain for 1j4h:
    23. Domain for 1j4i:
    24. Domains for 1j4r:
      1. 2165819Domain d1j4ra_: 1j4r A: [66389]
        complexed with 001, gol, so4
      2. 2165820Domain d1j4rb_: 1j4r B: [66390]
        complexed with 001, gol, so4
      3. 2165821Domain d1j4rd_: 1j4r D: [66391]
        complexed with 001, gol, so4
    25. Domain for 1nsg:
    26. Domains for 1qpf:
      1. 2165843Domain d1qpfa_: 1qpf A: [38411]
        complexed with 858, b7g
      2. 2165844Domain d1qpfd_: 1qpf D: [38412]
        complexed with 858, b7g
    27. Domains for 1qpl:
      1. 2165850Domain d1qpla_: 1qpl A: [38417]
        complexed with 587
      2. 2165851Domain d1qplc_: 1qpl C: [38418]
        complexed with 587
    28. Domain for 2dg3:
    29. Domain for 2dg4:
    30. Domain for 2dg9:
    31. Domain for 2fap:
    32. Domain for 2fke:
    33. Domain for 2ppn:
    34. Domain for 2ppo:
    35. Domain for 2ppp:
    36. Domain for 3fap:
    37. Domain for 3h9r:
    38. Domains for 3mdy:
      1. 2165830Domain d3mdyb1: 3mdy B:1-108 [181022]
        Other proteins in same PDB: d3mdya_, d3mdyb2, d3mdyc_, d3mdyd2
        automated match to d1a7xa_
        complexed with ldn
      2. 2165831Domain d3mdyd1: 3mdy D:1-108 [181024]
        Other proteins in same PDB: d3mdya_, d3mdyb2, d3mdyc_, d3mdyd2
        automated match to d1a7xa_
        complexed with ldn
    39. Domain for 4dh0:
    40. Domain for 4fap:
    41. Domain for 4ipx:
    42. Domain for 4n19:

More info for Protein FK-506 binding protein (FKBP12), an immunophilin from d.26.1.1: FKBP immunophilin/proline isomerase

Timeline for Protein FK-506 binding protein (FKBP12), an immunophilin from d.26.1.1: FKBP immunophilin/proline isomerase: