SCOPe 2.08: Protein: Aspartate beta-semialdehyde dehydrogenase

Lineage for Protein: Aspartate beta-semialdehyde dehydrogenase

Root: SCOPe 2.08
Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
The nucleotide-binding modes of this and the next two folds/superfamilies are similar

Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)
Family c.2.1.3: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain [51800] (22 proteins)
family members also share a common alpha+beta fold in C-terminal domain
Protein Aspartate beta-semialdehyde dehydrogenase [51813] (4 species)

Species:

Escherichia coli [TaxId:562] [51814] (4 PDB entries)
Uniprot P00353
1. Domains for 1brm:
  1. Domain d1brma1: 1brm A:1-133,A:355-367 [30030]
    Other proteins in same PDB: d1brma2, d1brmb2, d1brmc2
  2. Domain d1brmb1: 1brm B:1-133,B:355-367 [30031]
    Other proteins in same PDB: d1brma2, d1brmb2, d1brmc2
  3. Domain d1brmc1: 1brm C:1-133,C:355-367 [30032]
    Other proteins in same PDB: d1brma2, d1brmb2, d1brmc2
2. Domains for 1gl3:
  1. Domain d1gl3a1: 1gl3 A:1-133,A:355-367 [65282]
    Other proteins in same PDB: d1gl3a2, d1gl3b2
    complexed with cys, ndp
  2. Domain d1gl3b1: 1gl3 B:1-133,B:355-367 [65284]
    Other proteins in same PDB: d1gl3a2, d1gl3b2
    complexed with cys, ndp
3. Domains for 1t4b:
  1. Domain d1t4ba1: 1t4b A:1-133,A:355-367 [106406]
    Other proteins in same PDB: d1t4ba2, d1t4bb2
    complexed with na
  2. Domain d1t4bb1: 1t4b B:1-133,B:355-367 [106408]
    Other proteins in same PDB: d1t4ba2, d1t4bb2
    complexed with na
4. Domains for 1t4d:
  1. Domain d1t4da1: 1t4d A:1-133,A:355-367 [106412]
    Other proteins in same PDB: d1t4da2, d1t4db2, d1t4dc2
  2. Domain d1t4db1: 1t4d B:1-133,B:355-367 [106414]
    Other proteins in same PDB: d1t4da2, d1t4db2, d1t4dc2
  3. Domain d1t4dc1: 1t4d C:1-133,C:355-367 [106416]
    Other proteins in same PDB: d1t4da2, d1t4db2, d1t4dc2
Haemophilus influenzae [TaxId:727] [102159] (12 PDB entries)
Uniprot P44801
1. Domains for 1nwc:
  1. Domain d1nwca1: 1nwc A:1-133,A:358-371 [92229]
    Other proteins in same PDB: d1nwca2, d1nwcb2
  2. Domain d1nwcb1: 1nwc B:1-133,B:358-371 [92231]
    Other proteins in same PDB: d1nwca2, d1nwcb2
2. Domains for 1nwh:
  1. Domain d1nwha1: 1nwh A:1-133,A:358-371 [92233]
    Other proteins in same PDB: d1nwha2, d1nwhb2
  2. Domain d1nwhb1: 1nwh B:1-133,B:358-371 [92235]
    Other proteins in same PDB: d1nwha2, d1nwhb2
3. Domain for 1nx6:
  - Domain d1nx6a1: 1nx6 A:1-133,A:358-371 [92283]
    Other proteins in same PDB: d1nx6a2
    complexed with po4
4. Domain for 1oza:
  - Domain d1ozaa1: 1oza A:1-133,A:358-371 [104045]
    Other proteins in same PDB: d1ozaa2
    mutant
5. Domain for 1pqp:
  - Domain d1pqpa1: 1pqp A:1-133,A:358-371 [104286]
    Other proteins in same PDB: d1pqpa2
    complexed with hse, po4; mutant
6. Domains for 1pqu:
  1. Domain d1pqua1: 1pqu A:1-133,A:358-371 [104288]
    Other proteins in same PDB: d1pqua2, d1pqub2, d1pquc2, d1pqud2
    complexed with cac, cys, nap; mutant
  2. Domain d1pqub1: 1pqu B:1-133,B:358-371 [104290]
    Other proteins in same PDB: d1pqua2, d1pqub2, d1pquc2, d1pqud2
    complexed with cac, cys, nap; mutant
  3. Domain d1pquc1: 1pqu C:1-133,C:358-371 [104292]
    Other proteins in same PDB: d1pqua2, d1pqub2, d1pquc2, d1pqud2
    complexed with cac, cys, nap; mutant
  4. Domain d1pqud1: 1pqu D:1-133,D:358-371 [104294]
    Other proteins in same PDB: d1pqua2, d1pqub2, d1pquc2, d1pqud2
    complexed with cac, cys, nap; mutant
7. Domain for 1pr3:
  - Domain d1pr3a1: 1pr3 A:1-133,A:358-371 [104300]
    Other proteins in same PDB: d1pr3a2
    complexed with po4; mutant
8. Domain for 1ps8:
  - Domain d1ps8a1: 1ps8 A:1-133,A:358-371 [104304]
    Other proteins in same PDB: d1ps8a2
    mutant
9. Domain for 1pu2:
  - Domain d1pu2a1: 1pu2 A:1-133,A:358-371 [104308]
    Other proteins in same PDB: d1pu2a2
    mutant
10. Domains for 1q2x:
  1. Domain d1q2xa1: 1q2x A:1-133,A:358-371 [104503]
    Other proteins in same PDB: d1q2xa2, d1q2xb2
    mutant
  2. Domain d1q2xb1: 1q2x B:1-133,B:358-371 [104505]
    Other proteins in same PDB: d1q2xa2, d1q2xb2
    mutant
11. Domain for 1ta4:
  - Domain d1ta4a1: 1ta4 A:1-133,A:358-368 [112373]
    Other proteins in same PDB: d1ta4a2
    complexed with art
12. Domain for 1tb4:
  - Domain d1tb4a1: 1tb4 A:1-133,A:358-368 [112380]
    Other proteins in same PDB: d1tb4a2
    complexed with pej
Pneumococcus (Streptococcus pneumoniae) [TaxId:1313] [141917] (18 PDB entries)
Uniprot Q8DQ00 2-127,330-357
1. Domains for 2gyy:
  1. Domain d2gyya1: 2gyy A:2-127,A:330-357 [135879]
    Other proteins in same PDB: d2gyya2, d2gyyb2, d2gyyc2, d2gyyd2
  2. Domain d2gyyb1: 2gyy B:2-127,B:330-356 [135881]
    Other proteins in same PDB: d2gyya2, d2gyyb2, d2gyyc2, d2gyyd2
    automated match to d2gyya1
  3. Domain d2gyyc1: 2gyy C:2-127,C:330-358 [135883]
    Other proteins in same PDB: d2gyya2, d2gyyb2, d2gyyc2, d2gyyd2
    automated match to d2gyya1
  4. Domain d2gyyd1: 2gyy D:3-127,D:330-350 [135885]
    Other proteins in same PDB: d2gyya2, d2gyyb2, d2gyyc2, d2gyyd2
    automated match to d2gyya1
2. Domains for 2gz1:
  1. Domain d2gz1a1: 2gz1 A:2-127,A:330-358 [135887]
    Other proteins in same PDB: d2gz1a2, d2gz1b2
    automated match to d2gyya1
    complexed with nap
  2. Domain d2gz1b1: 2gz1 B:2-127,B:330-358 [135889]
    Other proteins in same PDB: d2gz1a2, d2gz1b2
    automated match to d2gyya1
    complexed with nap
3. Domains for 2gz2:
  1. Domain d2gz2a1: 2gz2 A:2-127,A:330-358 [135891]
    Other proteins in same PDB: d2gz2a2, d2gz2b2
    automated match to d2gyya1
    complexed with a2p
  2. Domain d2gz2b1: 2gz2 B:2-127,B:330-358 [135893]
    Other proteins in same PDB: d2gz2a2, d2gz2b2
    automated match to d2gyya1
    complexed with a2p
4. Domains for 2gz3:
  1. Domain d2gz3a1: 2gz3 A:2-127,A:330-358 [135895]
    Other proteins in same PDB: d2gz3a2, d2gz3b2, d2gz3c2, d2gz3d2
    automated match to d2gyya1
    complexed with as2, nap
  2. Domain d2gz3b1: 2gz3 B:2-127,B:330-348 [197992]
    Other proteins in same PDB: d2gz3a2, d2gz3b2, d2gz3c2, d2gz3d2
    automated match to d2gyya1
    complexed with as2, nap
  3. Domain d2gz3c1: 2gz3 C:2-127,C:330-358 [135897]
    Other proteins in same PDB: d2gz3a2, d2gz3b2, d2gz3c2, d2gz3d2
    automated match to d2gyya1
    complexed with as2, nap
  4. Domain d2gz3d1: 2gz3 D:2-127,D:330-358 [135899]
    Other proteins in same PDB: d2gz3a2, d2gz3b2, d2gz3c2, d2gz3d2
    automated match to d2gyya1
    complexed with as2, nap
5. Domains for 3pwk:
  1. Domain d3pwka1: 3pwk A:2-127,A:330-358 [214954]
    Other proteins in same PDB: d3pwka2, d3pwkb2, d3pwkb3
    automated match to d2gyya1
    complexed with 25a, edo, l14, na
  2. Domain d3pwkb1: 3pwk B:2-127,B:330-358 [214956]
    Other proteins in same PDB: d3pwka2, d3pwkb2, d3pwkb3
    automated match to d2gyya1
    complexed with 25a, edo, l14, na
6. Domains for 3pws:
  1. Domain d3pwsa1: 3pws A:2-127,A:330-358 [214958]
    Other proteins in same PDB: d3pwsa2, d3pwsb2
    automated match to d2gyya1
    complexed with 11c, a2p, na
  2. Domain d3pwsb1: 3pws B:2-127,B:330-358 [214960]
    Other proteins in same PDB: d3pwsa2, d3pwsb2
    automated match to d2gyya1
    complexed with 11c, a2p, na
7. Domains for 3pyl:
  1. Domain d3pyla1: 3pyl A:2-127,A:330-358 [214972]
    Other proteins in same PDB: d3pyla2, d3pyla3, d3pylb2, d3pylc2, d3pylc3, d3pyld2
    automated match to d2gyya1
    complexed with 2ra
  2. Domain d3pylb1: 3pyl B:2-127,B:330-355 [214974]
    Other proteins in same PDB: d3pyla2, d3pyla3, d3pylb2, d3pylc2, d3pylc3, d3pyld2
    automated match to d2gyya1
    complexed with 2ra
  3. Domain d3pylc1: 3pyl C:2-127,C:330-358 [214976]
    Other proteins in same PDB: d3pyla2, d3pyla3, d3pylb2, d3pylc2, d3pylc3, d3pyld2
    automated match to d2gyya1
    complexed with 2ra
  4. Domain d3pyld1: 3pyl D:2-127,D:330-357 [214978]
    Other proteins in same PDB: d3pyla2, d3pyla3, d3pylb2, d3pylc2, d3pylc3, d3pyld2
    automated match to d2gyya1
    complexed with 2ra
8. Domains for 3pyx:
  1. Domain d3pyxa1: 3pyx A:2-127,A:330-358 [214980]
    Other proteins in same PDB: d3pyxa2, d3pyxb2, d3pyxb3
    automated match to d2gyya1
    complexed with 12t, edo, na, nap
  2. Domain d3pyxb1: 3pyx B:2-127,B:330-358 [214982]
    Other proteins in same PDB: d3pyxa2, d3pyxb2, d3pyxb3
    automated match to d2gyya1
    complexed with 12t, edo, na, nap
9. Domains for 3pzb:
  1. Domain d3pzba1: 3pzb A:2-127,A:330-358 [214984]
    Other proteins in same PDB: d3pzba2, d3pzbb2, d3pzbb3
    automated match to d2gyya1
    complexed with 2ra, edo, na, nap
  2. Domain d3pzbb1: 3pzb B:2-127,B:330-358 [214986]
    Other proteins in same PDB: d3pzba2, d3pzbb2, d3pzbb3
    automated match to d2gyya1
    complexed with 2ra, edo, na, nap
10. Domains for 3q11:
  1. Domain d3q11a1: 3q11 A:2-127,A:330-358 [215017]
    Other proteins in same PDB: d3q11a2, d3q11a3, d3q11b2
    automated match to d2gyya1
    complexed with edo, na, nap, p4f
  2. Domain d3q11b1: 3q11 B:2-127,B:330-358 [215019]
    Other proteins in same PDB: d3q11a2, d3q11a3, d3q11b2
    automated match to d2gyya1
    complexed with edo, na, nap, p4f
11. Domains for 3q1l:
  1. Domain d3q1la1: 3q1l A:2-127,A:330-358 [215029]
    Other proteins in same PDB: d3q1la2, d3q1lb2, d3q1lc2, d3q1lc3, d3q1ld2
    automated match to d2gyya1
    complexed with dhl
  2. Domain d3q1lb1: 3q1l B:2-127,B:330-357 [215031]
    Other proteins in same PDB: d3q1la2, d3q1lb2, d3q1lc2, d3q1lc3, d3q1ld2
    automated match to d2gyya1
    complexed with dhl
  3. Domain d3q1lc1: 3q1l C:2-127,C:330-358 [215033]
    Other proteins in same PDB: d3q1la2, d3q1lb2, d3q1lc2, d3q1lc3, d3q1ld2
    automated match to d2gyya1
    complexed with dhl
  4. Domain d3q1ld1: 3q1l D:2-127,D:330-357 [215035]
    Other proteins in same PDB: d3q1la2, d3q1lb2, d3q1lc2, d3q1lc3, d3q1ld2
    automated match to d2gyya1
    complexed with dhl
12. Domains for 4r3n:
  1. Domain d4r3na1: 4r3n A:2-127,A:330-358 [261735]
    Other proteins in same PDB: d4r3na2, d4r3nb2
    automated match to d2gyya1
    complexed with 3gq, act, edo, na, nap
  2. Domain d4r3nb1: 4r3n B:2-127,B:330-348 [261670]
    Other proteins in same PDB: d4r3na2, d4r3nb2
    automated match to d2gyya1
    complexed with 3gq, act, edo, na, nap
13. Domains for 4r3w:
  1. Domain d4r3wa1: 4r3w A:2-127,A:330-358 [261557]
    Other proteins in same PDB: d4r3wa2, d4r3wb2
    automated match to d2gyya1
    complexed with 3gq, a2p, act, edo, na
  2. Domain d4r3wb1: 4r3w B:2-127,B:330-348 [261667]
    Other proteins in same PDB: d4r3wa2, d4r3wb2
    automated match to d2gyya1
    complexed with 3gq, a2p, act, edo, na
14. Domains for 4r41:
  1. Domain d4r41a1: 4r41 A:2-127,A:330-358 [261560]
    Other proteins in same PDB: d4r41a2, d4r41b2
    automated match to d2gyya1
    complexed with 4no, act, edo, na, nap
  2. Domain d4r41b1: 4r41 B:2-127,B:330-348 [261734]
    Other proteins in same PDB: d4r41a2, d4r41b2
    automated match to d2gyya1
    complexed with 4no, act, edo, na, nap
15. Domains for 4r4j:
  1. Domain d4r4ja1: 4r4j A:2-127,A:330-358 [261669]
    Other proteins in same PDB: d4r4ja2, d4r4ja3, d4r4jb2
    automated match to d2gyya1
    complexed with 3jl, edo, na, nap
  2. Domain d4r4jb1: 4r4j B:2-127,B:330-358 [261562]
    Other proteins in same PDB: d4r4ja2, d4r4ja3, d4r4jb2
    automated match to d2gyya1
    complexed with 3jl, edo, na, nap
16. Domains for 4r51:
  1. Domain d4r51a1: 4r51 A:2-127,A:330-358 [261566]
    Other proteins in same PDB: d4r51a2, d4r51a3, d4r51b2
    automated match to d2gyya1
    complexed with act, edo, na, nap, pht
  2. Domain d4r51b1: 4r51 B:2-127,B:330-348 [261739]
    Other proteins in same PDB: d4r51a2, d4r51a3, d4r51b2
    automated match to d2gyya1
    complexed with act, edo, na, nap, pht
17. Domains for 4r54:
  1. Domain d4r54a1: 4r54 A:2-127,A:330-358 [261678]
    Other proteins in same PDB: d4r54a2, d4r54b2
    automated match to d2gyya1
    complexed with 3jm, act, na, nap
  2. Domain d4r54b1: 4r54 B:2-127,B:330-358 [261675]
    Other proteins in same PDB: d4r54a2, d4r54b2
    automated match to d2gyya1
    complexed with 3jm, act, na, nap
18. Domains for 4r5h:
  1. Domain d4r5ha1: 4r5h A:2-127,A:330-358 [261674]
    Other proteins in same PDB: d4r5ha2, d4r5ha3, d4r5hb2
    automated match to d2gyya1
    complexed with 3jn, edo, na, nap
  2. Domain d4r5hb1: 4r5h B:2-127,B:330-358 [261741]
    Other proteins in same PDB: d4r5ha2, d4r5ha3, d4r5hb2
    automated match to d2gyya1
    complexed with 3jn, edo, na, nap
Vibrio cholerae [TaxId:666] [82297] (4 PDB entries)
1. Domains for 1mb4:
  1. Domain d1mb4a1: 1mb4 A:1-132,A:355-369 [78908]
    Other proteins in same PDB: d1mb4a2, d1mb4b2
    complexed with cys, ndp
  2. Domain d1mb4b1: 1mb4 B:1-132,B:355-369 [78910]
    Other proteins in same PDB: d1mb4a2, d1mb4b2
    complexed with cys, ndp
2. Domain for 1mc4:
  - Domain d1mc4a1: 1mc4 A:1-132,A:355-369 [84927]
    Other proteins in same PDB: d1mc4a2
3. Domains for 3pzr:
  1. Domain d3pzra1: 3pzr A:1-132,A:355-370 [214992]
    Other proteins in same PDB: d3pzra2, d3pzrb2
    automated match to d1mb4a1
    complexed with cys, na, nap
  2. Domain d3pzrb1: 3pzr B:1-132,B:355-370 [214994]
    Other proteins in same PDB: d3pzra2, d3pzrb2
    automated match to d1mb4a1
    complexed with cys, na, nap
4. Domains for 3q0e:
  1. Domain d3q0ea1: 3q0e A:1-132,A:355-369 [215007]
    Other proteins in same PDB: d3q0ea2, d3q0eb2
    automated match to d1mb4a1
    complexed with act, cys, edo, so4
  2. Domain d3q0eb1: 3q0e B:1-132,B:355-369 [215009]
    Other proteins in same PDB: d3q0ea2, d3q0eb2
    automated match to d1mb4a1
    complexed with act, cys, edo, so4

More info for Protein Aspartate beta-semialdehyde dehydrogenase from c.2.1.3: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain

Timeline for Protein Aspartate beta-semialdehyde dehydrogenase from c.2.1.3: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain:

Protein Aspartate beta-semialdehyde dehydrogenase from c.2.1.3: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain first appeared (with stable ids) in SCOP 1.55
Protein Aspartate beta-semialdehyde dehydrogenase from c.2.1.3: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain appears in SCOPe 2.07